{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:10:07Z","timestamp":1788970207297,"version":"build-2803163510"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T00:00:00Z","timestamp":1576195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>\n            Introduction\u2003Onodi cells are the most posterior ethmoid air cells, and extend superolaterally to the sphenoid sinus. The identification of Onodi cells is essential to because they can have some significant anatomic variations and relationships to vital adjacent structures, like the optic canal, the sphenoid sinus, and the internal carotid artery.<\/jats:p><jats:p>\n            Objective\u2003The present study aimed to assess the prevalence of Onodi cells and their position with respect to sphenoid sinus. To the authors' best knowledge, this is the first study that uses cone-beam computed tomography (CBCT) to assess the prevalence and position of Onodi cells.<\/jats:p><jats:p>\n            Methods\u2003We collected CBCT scan records from November 1st, 2016, to July 31st, 2017; the patients who fulfilled the eligibility criteria were included in the present study. The CBCT scans were reviewed by two independent observers. The descriptive statistics was performed using the Statistical Package for the Social Sciences (SPSS, SPSS, Inc., Chicago IL, US) software, version 17.0. A cross-tabulation of gender with the presence and position of Onodi cells was evaluated using the Chi-squared (\u03c72) test. The inter- and intraobserver agreements were evaluated using Kappa (\u03ba) statistics.<\/jats:p><jats:p>\n            Results\u2003Onodi cells were identified in 86 (42.8%) out of 201 patients. A subgroup analysis revealed that Onodi cells were present in 45 (43.3%) female and 41 (42.3%) male patients. The position of the Onodi cells was superior with respect to the sphenoid sinus in 43 (50%) of the patients, superolateral in 36 (41.9%), and lateral to the sphenoid sinus in 7 (8.1%) of the patients.<\/jats:p><jats:p>\n            Conclusion\u2003The present study indicated a high prevalence of Onodi cells, with approximately equal distribution among males and females, and mostly superior in position in relation to the sphenoid sinus.<\/jats:p>","DOI":"10.1055\/s-0039-1698779","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T09:02:42Z","timestamp":1576832562000},"page":"e319-e322","source":"Crossref","is-referenced-by-count":22,"title":["Imaging Analysis of Onodi Cells on Cone-Beam Computed Tomography"],"prefix":"10.1055","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3334-1317","authenticated-orcid":false,"given":"Ibrahim K.","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Nair Hospital Dental College, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaustubh","family":"Sansare","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Nair Hospital Dental College, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Freny","family":"Karjodkar","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Nair Hospital Dental College, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd","family":"Saalim","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Nair Hospital Dental College, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,12,13]]},"reference":[{"key":"ref1","volume-title":"The Optic Nerve and the Accessory Sinuses of the Nose","author":"A \u00d3nodi","year":"1910"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/000348949510410s01","article-title":"Paranasal sinuses:anatomic terminology and nomenclature","volume":"167","author":"H R Stammberger","year":"1995","journal-title":"Ann Otol Rhinol Laryngol Suppl"},{"key":"ref3","volume-title":"Endoscopic Pituitary Surgery: Endocrine, Neuro-Ophthalmologic and Surgical Management","author":"T Schwartz","year":"2011"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1097\/SCS.0000000000003580","article-title":"How to Expose the Entire Sella Floor With Minimal Manipulation During an Endoscopic Endonasal Transsphenoidal Approach","volume":"28","author":"D H Kim","year":"2017","journal-title":"J Craniofac Surg"},{"issue":"05","key":"ref5","doi-asserted-by":"crossref","first-page":"E2","DOI":"10.3171\/2011.3.FOCUS115","article-title":"Surgical nuances for removal of tuberculum sellae meningiomas with optic canal involvement using the endoscopic endonasal extended transsphenoidal transplanum transtuberculum approach","volume":"30","author":"J K Liu","year":"2011","journal-title":"Neurosurg Focus"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2500\/105065898781390325","article-title":"The reliability of computerized tomographic detection of the Onodi (Sphenoethmoid) cell","volume":"12","author":"J S Driben","year":"1998","journal-title":"Am J Rhinol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"365","DOI":"10.2500\/105065896781794851","article-title":"Surgical anatomy and variations of the Onodi cell","volume":"10","author":"D G Weinberger","year":"1996","journal-title":"Am J Rhinol"},{"issue":"03","key":"ref8","doi-asserted-by":"crossref","first-page":"329","DOI":"10.3109\/00016489409126065","article-title":"The optic nerve in the posterior ethmoid in Asians","volume":"114","author":"K H Yeoh","year":"1994","journal-title":"Acta Otolaryngol"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1177\/014556130308200314","article-title":"The prevalence of an Onodi cell in adult Thai cadavers","volume":"82","author":"S Thanaviratananich","year":"2003","journal-title":"Ear Nose Throat J"},{"issue":"01","key":"ref10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0385-8146(98)00024-8","article-title":"Anatomic variations of the paranasal sinuses: CT examination for endoscopic sinus surgery","volume":"26","author":"H Arslan","year":"1999","journal-title":"Auris Nasus Larynx"},{"issue":"02","key":"ref11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s00276-005-0073-9","article-title":"Risky anatomic variations of sphenoid sinus for surgery","volume":"28","author":"B Unal","year":"2006","journal-title":"Surg Radiol Anat"},{"issue":"06","key":"ref12","first-page":"763","article-title":"Anatomical variations of the lateral nasal wall and paranasal sinuses: A CT study for endoscopic sinus surgery (ESS) in Thai patients","volume":"88","author":"B Nitinavakarn","year":"2005","journal-title":"J Med Assoc Thai"},{"issue":"04","key":"ref13","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1177\/019459988709600405","article-title":"Relationship of the optic nerve to the paranasal sinuses as shown by computed tomography","volume":"96","author":"S F Bansberg","year":"1987","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"06","key":"ref14","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.otohns.2004.07.013","article-title":"Software-enabled CT analysis of optic nerve position and paranasal sinus pneumatization patterns","volume":"131","author":"P S Batra","year":"2004","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.ijporl.2017.04.001","article-title":"The prevalence of the Onodi cell - Most suitable method of CT evaluation in its detection","volume":"97","author":"L P Chmielik","year":"2017","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"01","key":"ref16","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1046\/j.1365-2273.1997.00862.x","article-title":"A study of the CT findings in 100 patients with rhinosinusitis and 100 controls","volume":"22","author":"N S Jones","year":"1997","journal-title":"Clin Otolaryngol Allied Sci"},{"issue":"02","key":"ref17","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.otohns.2008.05.014","article-title":"Anatomical variations of the paranasal sinuses in Polynesian and New Zealand European computerized tomography scans","volume":"139","author":"A Keast","year":"2008","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"02","key":"ref18","first-page":"101","article-title":"Prevalence of onodi cells in hospital raja permaisuri bainun, ipoh, malaysia","volume":"65","author":"K L Tan","year":"2010","journal-title":"Med J Malaysia"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1046\/j.1469-7580.2000.19720221.x","article-title":"Jimenez-Castellanos J. Anatomical variations in the human paranasal sinus region studied by CT","volume":"197","author":"P Perez","year":"2000","journal-title":"J Anat"},{"issue":"03","key":"ref20","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.ejrad.2003.08.012","article-title":"Remarkable anatomic variations in paranasal sinus region and their clinical importance","volume":"50","author":"M Kantarci","year":"2004","journal-title":"Eur J Radiol"},{"issue":"08","key":"ref21","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1177\/014556139807700804","article-title":"The Onodi (sphenoethmoid) cell","volume":"77","author":"E Yanagisawa","year":"1998","journal-title":"Ear Nose Throat J"},{"issue":"06","key":"ref22","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1177\/0194599811418040","article-title":"The Onodi cell: an obstacle to sellar lesions with a transsphenoidal approach","volume":"145","author":"J H Shin","year":"2011","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"07","key":"ref23","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1002\/lary.23346","article-title":"High-resolution computed tomography analysis of the prevalence of Onodi cells","volume":"122","author":"S Tomovic","year":"2012","journal-title":"Laryngoscope"},{"issue":"01","key":"ref24","doi-asserted-by":"crossref","first-page":"33","DOI":"10.5624\/isd.2017.47.1.33","article-title":"Cone-beam computed tomography analysis of accessory maxillary ostium and Haller cells: Prevalence and clinical significance","volume":"47","author":"I K Ali","year":"2017","journal-title":"Imaging Sci Dent"},{"issue":"02","key":"ref25","doi-asserted-by":"crossref","first-page":"e124","DOI":"10.1097\/SCS.0000000000004120","article-title":"Cone Beam Computed Tomography Assessment of Accessory Infraorbital Foramen and Determination of Infraorbital Foramen Position","volume":"29","author":"I K Ali","year":"2018","journal-title":"J Craniofac Surg"}],"container-title":["International Archives of Otorhinolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1698779.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:11:05Z","timestamp":1598573465000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1698779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,13]]},"references-count":25,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2020,7,31]]},"published-print":{"date-parts":[[2020,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1698779","relation":{},"ISSN":["1809-9777","1809-4864"],"issn-type":[{"value":"1809-9777","type":"print"},{"value":"1809-4864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,13]]}}}