{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:24:47Z","timestamp":1791645887074,"version":"4.3.4"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Neurol"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Myasthenia gravis is an antibody-mediated autoimmune disorder of the post-synaptic neuromuscular junction resulting in fluctuating, fatigable weakness. Most patients first present with extraocular symptoms (diplopia and\/or ptosis), and in 15% of cases symptoms will remain restricted to only the extraocular muscles (ocular myasthenia gravis [OMG]). The history and clinical examination are of the utmost importance in correctly identifying OMG patients, as supportive serologic or electrodiagnostic studies are frequently nondiagnostic. In this review, we outline a diagnostic approach to OMG (focusing on key clinical features), discuss therapeutic options, and highlight recent developments in the understanding of OMG.<\/jats:p>","DOI":"10.1055\/s-0039-1700527","type":"journal-article","created":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T18:31:10Z","timestamp":1576607470000},"page":"749-760","source":"Crossref","is-referenced-by-count":23,"title":["Update on Ocular Myasthenia Gravis"],"prefix":"10.1055","volume":"39","author":[{"given":"Meabh","family":"O'Hare","sequence":"additional","affiliation":[{"name":"Department of Neurology, Brigham & Women's Hospital, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Doughty","sequence":"additional","affiliation":[{"name":"Department of Neurology, Brigham & Women's Hospital, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,12,17]]},"container-title":["Seminars in Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1700527.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T06:01:26Z","timestamp":1576648886000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1700527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2019,12,17]]},"published-print":{"date-parts":[[2019,12]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1700527","relation":{},"ISSN":["0271-8235","1098-9021"],"issn-type":[{"value":"0271-8235","type":"print"},{"value":"1098-9021","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]}}}