{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T03:28:39Z","timestamp":1785554919234,"version":"3.56.0"},"reference-count":9,"publisher":"Scientific Scholar","license":[{"start":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T00:00:00Z","timestamp":1576022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ruralneuropractice.com"],"crossmark-restriction":true},"short-container-title":["JNRP"],"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>Brucellosis (malta fever) is a zoonotic infection caused by a gram-negative <jats:italic>coccobacillus<\/jats:italic> which is a facultative intracellular pathogen. It causes a chronic granulomatous infection, similar in histology to tuberculosis. Brucellosis remains a diagnostic dilemma due to misleading, nonspecific manifestations and increasing trend of unusual presentations. In brucellosis, the nervous system involvement occurs in only 5 to 7% of untreated patients, and it may manifest with encephalitis, meningoencephalitis, radiculitis, and peripheral and cranial neuropathies. Transverse myelitis is an unusual occurrence. Here, the authors are reporting an unusual case of neurobrucellosis in an elderly male patient who visited multiple hospitals with recurring febrile encephalopathy and paraparesis. The diagnosis was suspected by his occupational history of working as an abattoir worker and was confirmed by the presence of high titers of <jats:italic>Brucella<\/jats:italic> immunoglobulin (Ig) M and IgG antibodies in the serum. The patient was managed with injection gentamicin for 2 weeks along with oral course of doxycycline and rifampicin for 6 weeks. He made a good clinical recovery and went back to work with mild residual deficits.<\/jats:p>","DOI":"10.1055\/s-0039-1700600","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T23:46:57Z","timestamp":1576108017000},"page":"703-706","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Recurrent Encephalopathy with Transverse Myelitis: An Uncommon Presentation of Neurobrucellosis"],"prefix":"10.25259","volume":"10","author":[{"given":"Ravi K.","family":"Anadure","sequence":"first","affiliation":[{"name":"Department of Neurology, Command Hospital Air Force (CHAF), Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitesh","family":"Goel","sequence":"additional","affiliation":[{"name":"Department of Neurology, Command Hospital Air Force (CHAF), Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Command Hospital Air Force (CHAF), Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tushar","family":"Vidhale","sequence":"additional","affiliation":[{"name":"Department of Medicine, Command Hospital Air Force (CHAF), Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"issue":"2","key":"10.1055\/s-0039-1700600\/ref-1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S1473-3099(06)70382-6","article-title":"The new global map of human brucellosis","volume":"6","author":"Pappas","year":"2006","journal-title":"Lancet Infect Dis"},{"issue":"4","key":"10.1055\/s-0039-1700600\/ref-2","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s12038-008-0072-1","article-title":"Brucellosis in India - a review","volume":"33","author":"Mantur","year":"2008","journal-title":"J Biosci"},{"issue":"22","key":"10.1055\/s-0039-1700600\/ref-3","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1056\/NEJMra050570","article-title":"Brucellosis","volume":"352","author":"Pappas","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1055\/s-0039-1700600\/ref-4","first-page":"1","article-title":"Brucellosis","author":"Beeching","year":"2015","edition":"19"},{"issue":"1","key":"10.1055\/s-0039-1700600\/ref-5","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S1413-8670(11)70140-4","article-title":"Neurobrucellosis: clinical, diagnostic, therapeutic features and outcome. Unusual clinical presentations in an endemic region","volume":"15","author":"Ceran","year":"2011","journal-title":"Braz J Infect Dis"},{"issue":"2","key":"10.1055\/s-0039-1700600\/ref-6","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.nic.2015.01.004","article-title":"Spinal brucellosis","volume":"25","author":"Tali","year":"2015","journal-title":"Neuroimaging Clin N Am"},{"key":"10.1055\/s-0039-1700600\/ref-7","first-page":"2019535","article-title":"Neurobrucellosis: a case report from himachal pradesh, india, and review of the literature","volume":"2016","author":"Raina","year":"2016","journal-title":"Case Rep Infect Dis"},{"issue":"2","key":"10.1055\/s-0039-1700600\/ref-8","doi-asserted-by":"crossref","first-page":"e32090","DOI":"10.1371\/journal.pone.0032090","article-title":"Systematic review and meta-analysis of randomized clinical trials in the treatment of human brucellosis","volume":"7","author":"Solis Garc\u00eda del Pozo","year":"2012","journal-title":"PLoS One"},{"key":"10.1055\/s-0039-1700600\/ref-9","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1136\/bmj.39497.500903.25","article-title":"Treatment of human brucellosis: systematic review and meta-analysis of randomised controlled trials","volume":"336","author":"Skalsky","year":"2008","journal-title":"BMJ"}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ruralneuropractice.com\/recurrent-encephalopathy-with-transverse-myelitis-an-uncommon-presentation-of-neurobrucellosis\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ruralneuropractice.com\/recurrent-encephalopathy-with-transverse-myelitis-an-uncommon-presentation-of-neurobrucellosis\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:41:41Z","timestamp":1691210501000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/recurrent-encephalopathy-with-transverse-myelitis-an-uncommon-presentation-of-neurobrucellosis\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,11]]},"references-count":9,"alternative-id":["10.1055\/s-0039-1700600"],"URL":"https:\/\/doi.org\/10.1055\/s-0039-1700600","relation":{},"ISSN":["0976-3147"],"issn-type":[{"value":"0976-3147","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,11]]},"article-number":"703"}}