{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:42:56Z","timestamp":1740166976711,"version":"3.37.3"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T00:00:00Z","timestamp":1576195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003The association between prenatal Zika virus infection and hearing alterations in offspring has been the object of some studies, although few have assessed children without microcephaly. However, a current trend to include prenatal Zika virus exposure in the group of risk indicators for hearing loss is noted.<\/jats:p><jats:p>\n          Objective\u2003To present a series of 27 children prenatally exposed to the Zika virus submitted to multiple hearing assessments over time.<\/jats:p><jats:p>\n          Methods\u2003A cohort of children born to symptomatic mothers with laboratorial Zika virus infection confirmation during pregnancy was submitted to an otoacoustic emission test, auditory brainstem response test (automated, neurodiagnostic and frequency-specific), audiometry, and imitanciometry over a period of 36 months since birth. The hearing assessment was performed independently of the presence of microcephaly or other apparent signs of congenital Zika syndrome.<\/jats:p><jats:p>\n          Results\u2003The hearing tests presented predominantly normal results. Some children had signs of middle ear pathology. The only microcephalic child had normal electrophysiological tests, as well as preserved audiometric thresholds, but presented altered motor responses to sound.<\/jats:p><jats:p>\n          Conclusion\u2003Prenatal exposure to Zika virus does not always determine hearing impairment. This risk seems to be more associated to the severity of the central nervous system damage. Hearing screening and follow-ups of the affected children are important, as well as further research in this area.<\/jats:p>","DOI":"10.1055\/s-0039-3399539","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T09:02:42Z","timestamp":1576832562000},"page":"e299-e307","source":"Crossref","is-referenced-by-count":5,"title":["Normal Hearing Function in Children Prenatally Exposed to Zika Virus"],"prefix":"10.1055","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0298-1765","authenticated-orcid":false,"given":"Maria Helena Magalh\u00e3es","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Universidade Federal do Rio de Janeiro, Hospital Universit\u00e1rio Clementino Fraga Filho, Rio de Janeiro, RJ, Brazil"},{"name":"Department of Pediatrics, Instituto D'Or de Pesquisa e Ensino, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiane Fregonesi Dutra","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Phonoaudiology, Universidade Federal do Rio de Janeiro Hospital Universit\u00e1rio Clementino Fraga Filho, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Clara de","family":"Magalh\u00e3es Barbosa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Instituto D'Or de Pesquisa e Ensino, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaqueline Rodrigues","family":"Robaina","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Instituto D'Or de Pesquisa e Ensino, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaldo","family":"Prata-Barbosa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Instituto D'Or de Pesquisa e Ensino, Rio de Janeiro, RJ, Brazil"},{"name":"Department of Pediatrics, Universidade Federal do Rio de Janeiro Maternidade Escola, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Antonio de Melo Tavares de","family":"Lima","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Universidade Federal do Rio de Janeiro, Hospital Universit\u00e1rio Clementino Fraga Filho, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Jos\u00e9 Ledo Alves da","family":"Cunha","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Universidade Federal do Rio de Janeiro Maternidade Escola, Rio de Janeiro, RJ, Brazil"},{"name":"Department of Pediatrics, Universidade Federal do Rio de Janeiro, Instituto de Puericultura e Pediatria Martag\u00e3o Gesteira, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,12,13]]},"reference":[{"key":"ref1","first-page":"1","article-title":"Caldas Neto S da S, van der Linden V, Ramos RCF. 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