{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T14:45:28Z","timestamp":1794408328662,"version":"4.9.0"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003This study was aimed to compare the closure of skull base defect in endoscopic endonasal transsphenoid surgery of pituitary tumors, using bipedicled nasal septal flap versus fascial closure. The study hypothesis being that bipedicled nasal septal flap is better, compared with fascial closure of skull base defect post\u2013endoscopic endonasal transsphenoid surgery of pituitary tumors.<\/jats:p><jats:p>\n          Methods\u2003All the eligible patients were randomly divided into two groups and then randomly allocated to the surgeons. In one group, fat and fascia lata was used for closure of the skull base defect and nasal septal flap was not harvested whereas in the other, nasal septal flap was used for closure.<\/jats:p><jats:p>\n          Results\u2003There was a statistically significant difference in postoperative cerebrospinal fluid leak between the two groups. Patients who had undergone flap repair had lower incidence of postoperative cerebrospinal fluid (CSF) leak. Duration of postoperative hospital stay was also less among the group who underwent flap repair (statistically significant).<\/jats:p><jats:p>\n          Conclusion\u2003Bipedicled nasal septal flap serves an excellent cover for the skull base defect following endoscopic endonasal transsphenoidal pituitary surgery. It can prevent postoperative CSF leak even in cases where tissue glue is not used.<\/jats:p>","DOI":"10.1055\/s-0039-3400224","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T00:03:15Z","timestamp":1573776195000},"page":"313-320","source":"Crossref","is-referenced-by-count":1,"title":["Study on Closure of Skull Base Defect Post\u2013Endoscopic Endonasal Transsphenoid Pituitary Surgery: A Novel Flap Design"],"prefix":"10.1055","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0959-7432","authenticated-orcid":false,"given":"Gokul","family":"Gopi","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurav","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Department of ENT and HNS, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudipta","family":"Mohakud","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashis","family":"Patnaik","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Preetam","sequence":"additional","affiliation":[{"name":"Department of ENT and HNS, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabi Narayan","family":"Sahu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradipta Ku","family":"Parida","sequence":"additional","affiliation":[{"name":"Department of ENT and HNS, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,11,14]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1097\/00005537-200007000-00019","article-title":"Transnasal endoscopic repair of cerebrospinal fluid rhinorrhea: a meta-analysis","volume":"110","author":"H M 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