{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:21Z","timestamp":1740126801100,"version":"3.37.3"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"07","funder":[{"name":"NICHD","award":["U10 HD063020"],"award-info":[{"award-number":["U10 HD063020"]}]},{"name":"NICHD","award":["U10 HD063037"],"award-info":[{"award-number":["U10 HD063037"]}]},{"name":"NICHD","award":["U10 HD063041"],"award-info":[{"award-number":["U10 HD063041"]}]},{"name":"NICHD","award":["U10 HD063046"],"award-info":[{"award-number":["U10 HD063046"]}]},{"name":"NICHD","award":["U10 HD063047"],"award-info":[{"award-number":["U10 HD063047"]}]},{"name":"NICHD","award":["U10 HD063048"],"award-info":[{"award-number":["U10 HD063048"]}]},{"name":"NICHD","award":["U10 HD063053"],"award-info":[{"award-number":["U10 HD063053"]}]},{"name":"NICHD","award":["U10 HD063072"],"award-info":[{"award-number":["U10 HD063072"]}]},{"name":"NICHD","award":["1K12 HD085816"],"award-info":[{"award-number":["1K12 HD085816"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003Our objective was to test the association of fetal adrenal size with perinatal morbidity among fetuses with fetal growth restriction (FGR; estimated fetal weight [EFW]\u2009&lt;\u200910th percentile).<\/jats:p><jats:p>\n          Study Design\u2003This was a secondary analysis of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b) adrenal study, which measured fetal adrenal gland size at 22 to 30 weeks' gestation. We analyzed the transverse adrenal area (TAA) and fetal zone area (absolute measurements and corrected for fetal size) and the ratio of the fetal zone area to the total transverse area using a composite perinatal outcome of stillbirth, neonatal intensive care unit admission, respiratory distress syndrome, necrotizing enterocolitis, retinopathy of prematurity, sepsis, mechanical ventilation, seizure, or death. Among fetuses with FGR, adrenal measurements were compared between those that did and did not experience the composite perinatal outcome.<\/jats:p><jats:p>\n          Results\u2003There were 1,709 eligible neonates. Seven percent (n\u2009=\u2009120) were diagnosed with FGR at the time of adrenal measurement, and 14.7% (n\u2009=\u2009251) experienced perinatal morbidity. EFW-corrected and absolute adrenal measurements were similar among fetuses with and without FGR as well as among those who did and did not experience morbidity. The area under the curve for corrected TAA was 0.52 (95% confidence interval 0.38\u20130.67).<\/jats:p><jats:p>\n          Conclusion\u2003In our cohort, adrenal size was not associated with risk of morbidity among fetuses with FGR.<\/jats:p>","DOI":"10.1055\/s-0039-3400308","type":"journal-article","created":{"date-parts":[[2019,11,23]],"date-time":"2019-11-23T00:45:13Z","timestamp":1574469913000},"page":"676-682","source":"Crossref","is-referenced-by-count":4,"title":["Antenatal Fetal Adrenal Measurements at 22 to 30 Weeks' Gestation, Fetal Growth Restriction, and Perinatal Morbidity"],"prefix":"10.1055","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2187-3428","authenticated-orcid":false,"given":"Nathan R.","family":"Blue","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2927-8693","authenticated-orcid":false,"given":"Matthew","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Christiana Care Health System, Wilmington, Delaware"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda A.","family":"Allshouse","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A.","family":"Grobman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyagriv N.","family":"Simhan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital of UPMC, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozhan M.","family":"Turan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Parry","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith H.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of California, Irvine, Orange, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uma","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, Yale University, New Haven, Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Haas","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Myers","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City, Kansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Mercer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, MetroHealth Medical Center, Cleveland, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George R.","family":"Saade","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Silver","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,11,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S0140-6736(03)14466-2","article-title":"Cerebral palsy and intrauterine growth in single births: European collaborative study","volume":"362","author":"S Jarvis","year":"2003","journal-title":"Lancet"},{"issue":"16","key":"ref2","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1056\/NEJM199904223401603","article-title":"Birth weight in relation to morbidity and mortality among newborn infants","volume":"340","author":"D D McIntire","year":"1999","journal-title":"N Engl J 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One"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-3400308.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T22:36:37Z","timestamp":1622241397000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-3400308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,22]]},"references-count":17,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2021,5,28]]},"published-print":{"date-parts":[[2021,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-3400308","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"type":"print","value":"0735-1631"},{"type":"electronic","value":"1098-8785"}],"subject":[],"published":{"date-parts":[[2019,11,22]]}}}