{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T21:38:03Z","timestamp":1649108283954},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"02","funder":[{"name":"National Center for Advancing Translational Sciences\/National Institutes of Health","award":["UL1TR000445"],"award-info":[{"award-number":["UL1TR000445"]}]},{"name":"U.S. Department of Veterans Affairs BLRD CDA2","award":["IK2BX001634"],"award-info":[{"award-number":["IK2BX001634"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Jnl Wrist Surg"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003This article reviews the results of a surgical technique using three iterations of drilling, autologous cancellous bone grafting (filling), and use of an intraosseous compression screw for the treatment of nondisplaced or minimally displaced scaphoid delayed unions or nonunions.<\/jats:p><jats:p>\n          Methods\u2003Part 1\u2014Cadaveric study: Three cadaveric scaphoids underwent stained cancellous bone graft packing and headless cannulated compression screw placement using a single iteration of drilling and graft packing. Three additional scaphoids were allocated to the triple \u201cdrill and fill\u201d group, and underwent three iterations of drilling and graft packing before screw insertion. Graft particle distribution on mid-sagittal sections was assessed under fluorescence microscopy. Comparison of normalized areas between the single and triple \u201cdrill and fill\u201d groups was performed using repeated measures ANOVA and Tukey's post hoc test.<\/jats:p><jats:p>Part 2\u2014Clinical study: Twelve patients with minimally displaced scaphoid delayed unions and nonunions treated between April 2007 and December 2013 with the triple \u201cdrill and fill\u201d technique were included. The average follow-up was 60.4 weeks. Two fellowship-trained musculoskeletal radiologists independently reviewed images for fracture healing.<\/jats:p><jats:p>\n          Results\u2003By the histomorphometric analysis, there was improved autograft distribution along the screw tract, particularly within the proximal pole, with three iterations of drilling and filling. Clinically, 11 of 12 delayed unions and nonunions had healed.<\/jats:p><jats:p>\n          Conclusion\u2003Our results support the use of the \u201cdrill and fill\u201d technique as an option for the treatment of select nondisplaced or minimally displaced scaphoid nonunions and delayed unions at the waist without avascular necrosis of the proximal pole.<\/jats:p><jats:p>\n          Level of Evidence\u2003This is a Level IV study.<\/jats:p>","DOI":"10.1055\/s-0039-3400510","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T00:28:27Z","timestamp":1574814507000},"page":"116-123","source":"Crossref","is-referenced-by-count":0,"title":["Drill and Fill Technique for the Treatment of Scaphoid Delayed Unions and Nonunions"],"prefix":"10.1055","volume":"09","author":[{"given":"Dennis S.","family":"Lee","sequence":"additional","affiliation":[{"name":"Integrated Health Associates, Michigan Orthopaedic Center, Ypsilanti, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David T.","family":"Lee","sequence":"additional","affiliation":[{"name":"Notre Dame Seminary, Graduate School of Theology, Program of Priestly Formation, New Orleans, Louisiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sasidhar","family":"Uppuganti","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Vanderbilt University Medical Center, Vanderbilt, Nashville, Tennessee"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel S.","family":"Perrien","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"Nicholas D.","family":"Pappas","sequence":"additional","affiliation":[{"name":"Hand Surgical Associates, Metairie, Louisiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaitlyn","family":"Reasoner","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Vanderbilt University Medical Center, Vanderbilt, Nashville, Tennessee"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,11,26]]},"container-title":["Journal of Wrist Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-3400510.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,2]],"date-time":"2020-04-02T13:29:57Z","timestamp":1585834197000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-3400510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,26]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2020,4,1]]},"published-print":{"date-parts":[[2020,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-3400510","relation":{},"ISSN":["2163-3916","2163-3924"],"issn-type":[{"value":"2163-3916","type":"print"},{"value":"2163-3924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,26]]}}}