{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T00:45:37Z","timestamp":1781311537746,"version":"3.54.1"},"reference-count":35,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003Maternal racial and ethnic disparities exist in obstetric outcomes. The contribution of paternal race and ethnicity toward obstetric outcomes has been less well documented. The objective of this study was to investigate the association between paternal race and ethnicity and several adverse pregnancy outcomes.<\/jats:p><jats:p>\n          Study Design\u2003This was a retrospective cohort of birth data from the CDC National Vital Statistics, years 2013\u20142017. All singleton live births were included in the analysis. Records with missing paternal race and ethnicity were excluded. The primary dependent variables were the following adverse maternal and perinatal outcomes: gestational diabetes, hypertensive disorder of pregnancy, preterm birth &lt;37 weeks, cesarean delivery, low birth weight &lt;2,500\u2009g, 5-minute Apgar's score &lt;7, admission to neonatal intensive care unit (NICU), and assisted ventilation at\u2009&gt;\u20096\u2009hours of life. The main exposure was paternal race and ethnicity, which was grouped into non-Hispanic white, non-Hispanic black, Hispanic, and other. Other race and ethnicity category included: American Indian, Alaskan Native, Asian, Native Hawaiian, or other Pacific Islander. Univariable and multivariable analyses were done to determine whether paternal race and ethnicity was independently associated with adverse pregnancy outcomes.<\/jats:p><jats:p>\n          Results\u2003A total of 16,482,745 births were included. In univariable analysis, all adverse obstetric outcomes were significantly associated with paternal race and ethnicity. In multivariable analysis, controlling for maternal and paternal demographic characteristics and maternal clinical factors, paternal race and ethnicity remained significantly associated with the majority of the adverse pregnancy outcomes. The strongest association was seen with: (1) paternal non-Hispanic black race and ethnicity, and higher rates of LBW and preterm birth (Odds ratio [OR]\u2009=\u20091.25, 95% CI: 1.24\u20131.27 and OR\u2009=\u20091.14, 95% CI: 1.13\u20131.15, respectively); (2) paternal Hispanic race and ethnicity and lower rates of 5-minute Apgar's score &lt;7, and assisted ventilation at &gt;6\u2009hours of life (OR\u2009=\u20090.78, 95% CI: 0.77\u20130.79, and OR\u2009=\u20090.77, 95% CI: 0.75\u20130.78, respectively); and (3) other paternal race and ethnicity and higher rates of gestational diabetes, but lower rates of hypertensive disorder of pregnancy and assisted ventilation &gt;6\u2009hours of life (OR\u2009=\u20091.26, 95% CI: 1.25\u20131.27; OR\u2009=\u20090.79, 95% CI: 0.78\u20130.80; and OR\u2009=\u20090.80, 95% CI: 0.78\u20130.82, respectively). All associations were in comparison to paternal non-Hispanic white race and ethnicity.<\/jats:p><jats:p>\n          Conclusion\u2003Paternal race and ethnicity has an independent association with adverse obstetric outcomes. The pathway and the extent of the paternal racial influence are not fully understood and deserve additional research.<\/jats:p>","DOI":"10.1055\/s-0039-3400995","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T08:40:07Z","timestamp":1576831207000},"page":"698-706","source":"Crossref","is-referenced-by-count":11,"title":["The Association of Paternal Race and Ethnicity with Adverse Pregnancy Outcomes in a Contemporary U.S. Cohort"],"prefix":"10.1055","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6568-0201","authenticated-orcid":false,"given":"Anna","family":"Palatnik","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin"},{"name":"Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Garacci","sequence":"additional","affiliation":[{"name":"Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebekah J.","family":"Walker","sequence":"additional","affiliation":[{"name":"Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, Wisconsin"},{"name":"Division of General Internal Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukoso N.","family":"Ozieh","sequence":"additional","affiliation":[{"name":"Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joni S.","family":"Williams","sequence":"additional","affiliation":[{"name":"Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, Wisconsin"},{"name":"Division of General Internal Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard E.","family":"Egede","sequence":"additional","affiliation":[{"name":"Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, Wisconsin"},{"name":"Division of General Internal Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,12,13]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.ajog.2009.10.864","article-title":"Racial\/ethnic disparities in obstetric outcomes and care: prevalence and determinants","volume":"202","author":"A S Bryant","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1097\/AOG.0000000000002534","article-title":"Health care disparity and pregnancy-related mortality in the United States, 2005\u20132014","volume":"131","author":"A Moaddab","year":"2018","journal-title":"Obstet Gynecol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1097\/AOG.0000000000002937","article-title":"Racial and ethnic disparities in the incidence of severe maternal morbidity in the United States, 2012\u20132015","volume":"132","author":"L K Admon","year":"2018","journal-title":"Obstet Gynecol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1675207","article-title":"Racial and ethnic disparities in maternal outcomes and the disadvantage of peripartum black women: a multistate analysis, 2007\u20132014","author":"V Tangel","year":"2018","journal-title":"Am J Perinatol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1053\/j.semperi.2017.04.003","article-title":"Racial and ethnic differences in contraception use and obstetric outcomes: a review","volume":"41","author":"A V Jackson","year":"2017","journal-title":"Semin Perinatol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1053\/j.semperi.2017.08.010","article-title":"Racial and ethnic differences in preterm birth: a complex, multifactorial problem","volume":"41","author":"T A Manuck","year":"2017","journal-title":"Semin Perinatol"},{"key":"ref7","first-page":"328","article-title":"Eunice Kennedy Shriver National Institute of Child Healthand Human Development Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nuMoM2b) Network*. Racial disparities in adverse pregnancy outcomes and psychosocial stress","volume":"131","author":"W A Grobman","year":"2018","journal-title":"Obstet Gynecol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"506","DOI":"10.3109\/10641955.2015.1090581","article-title":"Racial disparities in comorbidities, complications, and maternal and fetal outcomes in women with preeclampsia\/eclampsia","volume":"34","author":"S Shahul","year":"2015","journal-title":"Hypertens Pregnancy"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1177\/003335491012500413","article-title":"Disparities in maternal hypertension and pregnancy outcomes: evidence from North Carolina, 1994\u20132003","volume":"125","author":"M L Miranda","year":"2010","journal-title":"Public Health Rep"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"163","DOI":"10.2105\/AJPH.2005.068577","article-title":"Racial disparity in hypertensive disorders of pregnancy in New York state: a 10-year longitudinal population-based study","volume":"97","author":"M Tanaka","year":"2007","journal-title":"Am J Public Health"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.amepre.2015.01.026","article-title":"Trends in gestational diabetes among hospital deliveries in 19 U.S. states, 2000\u20132010","volume":"49","author":"B H Bardenheier","year":"2015","journal-title":"Am J Prev Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"616.e1","DOI":"10.1016\/j.ajog.2010.01.082","article-title":"Maternal and paternal race\/ethnicity are both associated with gestational diabetes","volume":"202","author":"A B Caughey","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.ajog.2015.03.011","article-title":"The prevalence of gestational diabetes mellitus recurrence \u2013 effect of ethnicity and parity: a metaanalysis","volume":"213","author":"N Schwartz","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1159\/000480536","article-title":"Racial and ethnic disparities in preterm infant mortality and sever morbidity: a population-based study","volume":"113","author":"J G Anderson","year":"2018","journal-title":"Neonatology"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.ajog.2016.11.1026","article-title":"Racial\/ethnic differences in preterm perinatal outcomes","volume":"216","author":"M E Wallace","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/jamapediatrics.2018.2029","article-title":"Association of race\/ethnicity with very preterm neonatal morbidities","volume":"172","author":"T Janevic","year":"2018","journal-title":"JAMA Pediatr"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3934\/publichealth.2018.3.312","article-title":"Paternal race\/ethnicity and risk of adverse birth outcomes in the United States, 1989\u20132013","volume":"5","author":"Y Li","year":"2018","journal-title":"AIMS Public Health"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.2105\/AJPH.2016.303242","article-title":"Parental race\/ethnicity and adverse birth outcomes in New York City: 2000\u20132010","volume":"106","author":"L N Borrell","year":"2016","journal-title":"Am J Public Health"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1186\/s12884-014-0385-z","article-title":"Paternal race\/ethnicity and very low birth weight","volume":"14","author":"K G Fulda","year":"2014","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1089\/jwh.2009.1561","article-title":"Prematurity and low birth weight as potential mediators of higher stillbirth risk in mixed black\/white race couples","volume":"19","author":"K J Gold","year":"2010","journal-title":"J Womens Health (Larchmt)"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1111\/j.1600-0412.2012.01501.x","article-title":"Biracial couples and adverse birth outcomes: a systematic review and meta-analyses","volume":"91","author":"R M Srinivasjois","year":"2012","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1080\/14767058.2017.1293029","article-title":"Risk for spontaneous preterm birth among inter-racial\/ethnic couples","volume":"31","author":"B Z Shachar","year":"2018","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1097\/01.AOG.0000164478.91731.06","article-title":"Maternal ethnicity, paternal ethnicity, and parental ethnic discordance: predictors of preeclampsia","volume":"106","author":"A B Caughey","year":"2005","journal-title":"Obstet Gynecol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/01.AOG.0000165274.06811.86","article-title":"Adverse perinatal outcomes among interracial couples in the United States","volume":"106","author":"D Getahun","year":"2005","journal-title":"Obstet Gynecol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s10995-017-2407-8","article-title":"Fathers count: the impact of paternal risk factors on birth outcomes","volume":"22","author":"Y Meng","year":"2018","journal-title":"Matern Child Health J"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3233\/NPM-1356111","article-title":"Hypertensive disease in pregnancy: an examination of ethnic differences and the Hispanic paradox","volume":"6","author":"A Carr","year":"2013","journal-title":"J Neonatal Perinatal Med"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.socscimed.2004.08.029","article-title":"What does skin color have to do with infant health? An analysis of low birth weight among mainland and island Puerto Ricans","volume":"61","author":"N S Landale","year":"2005","journal-title":"Soc Sci Med"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e21","DOI":"10.1136\/jech.2009.103879","article-title":"Are black Hispanics black or Hispanic? Exploring disparities at the intersection of race and ethnicity","volume":"66","author":"T A LaVeist-Ramos","year":"2011","journal-title":"J Epidemiol Community Health"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.3389\/fphys.2018.01870","article-title":"Paternal Determinants in Preeclampsia","volume":"9","author":"C Galaviz-Hernandez","year":"2019","journal-title":"Front Physiol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1056\/NEJM200103223441201","article-title":"Paternal and maternal components of the predisposition to preeclampsia","volume":"344","author":"M S Esplin","year":"2001","journal-title":"N Engl J Med"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/S0140-6736(94)91638-1","article-title":"Association of pregnancy-induced hypertension with duration of sexual cohabitation before conception","volume":"344","author":"P Y Robillard","year":"1994","journal-title":"Lancet"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1056\/NEJMoa011379","article-title":"The interval between pregnancies and the risk of preeclampsia","volume":"346","author":"R Skjaerven","year":"2002","journal-title":"N Engl J Med"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.fertnstert.2008.12.021","article-title":"Is the use of donor sperm associated with a higher incidence of preeclampsia in women who achieve pregnancy after intrauterine insemination?","volume":"93","author":"D Kyrou","year":"2010","journal-title":"Fertil Steril"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s12041-010-0060-8","article-title":"Comparing genetic ancestry and self-reported race\/ethnicity in a multiethnic population in New York City","volume":"89","author":"Y L Lee","year":"2010","journal-title":"J Genet"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.2105\/AJPH.2007.117127","article-title":"Paternal race\/ethnicity and birth outcomes","volume":"98","author":"S Ma","year":"2008","journal-title":"Am J Public Health"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-3400995.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T22:37:42Z","timestamp":1622241462000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-3400995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,13]]},"references-count":35,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2021,5,28]]},"published-print":{"date-parts":[[2021,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-3400995","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,13]]}}}