{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T15:24:01Z","timestamp":1788276241298,"version":"build-2803163510"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003This study estimates the association of a first trimester finding of subchorionic hematoma (SCH) with third trimester adverse pregnancy outcomes in women with twin pregnancies.<\/jats:p><jats:p>\n          Study Design\u2003Retrospective cohort study of twin pregnancies prior to 14 weeks at a single institution from 2005 to 2019, all of whom had a first trimester ultrasound. We excluded monoamniotic twins, fetal anomalies, history of fetal reduction or spontaneous reduction, and twin-to-twin transfusion syndrome. Ultrasound data were reviewed, and we compared pregnancy outcomes after 24 weeks in women with and without a SCH at their initial ultrasound 60\/7 to 136\/7 weeks. Regression analysis was used to control for any differences in baseline characteristics.<\/jats:p><jats:p>\n          Results\u2003A total of 760 women with twin pregnancies met inclusion criteria for the study, 68 (8.9%) of whom had a SCH. Women with SCH were more likely to have vaginal bleeding and had their initial ultrasound at earlier gestational ages. On univariate analysis, SCH was not significantly associated with gestational age at delivery, preterm birth, birthweight of either twin, low birthweight percentiles of either twin, fetal demise, or preeclampsia. SCH was associated with placental abruption on univariate analysis, but not after controlling for vaginal bleeding and gestational age at the time of the initial ultrasound (adjusted odds ratio: 2.00, 95% confidence interval: 0.63\u20136.42). Among women with SCH, SCH size was not associated with adverse pregnancy outcomes.<\/jats:p><jats:p>\n          Conclusion\u2003In women with twin pregnancies, the finding of a first trimester SCH is not associated with adverse pregnancy outcomes &gt;24 weeks.<\/jats:p>","DOI":"10.1055\/s-0039-3401852","type":"journal-article","created":{"date-parts":[[2019,12,30]],"date-time":"2019-12-30T23:35:09Z","timestamp":1577748909000},"page":"779-783","source":"Crossref","is-referenced-by-count":10,"title":["Subchorionic Hematomas and Adverse Pregnancy Outcomes among Twin Pregnancies"],"prefix":"10.1055","volume":"38","author":[{"given":"Mariam","family":"Naqvi","sequence":"additional","affiliation":[{"name":"Maternal Fetal Medicine Associates, PLLC, New York, New York"},{"name":"Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mackenzie N.","family":"Naert","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanaa","family":"Khadraoui","sequence":"additional","affiliation":[{"name":"Touro College of Osteopathic Medicine, Harlem, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto M.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amalia G.","family":"Namath","sequence":"additional","affiliation":[{"name":"Georgetown University School of Medicine, Washington, District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munira","family":"Ali","sequence":"additional","affiliation":[{"name":"Touro College of Osteopathic Medicine, Harlem, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan S.","family":"Fox","sequence":"additional","affiliation":[{"name":"Maternal Fetal Medicine Associates, PLLC, New York, New York"},{"name":"Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,12,30]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0020-7292(98)00153-2","article-title":"Persistent subchorionic hematoma with clinical symptoms until delivery","volume":"63","author":"H Seki","year":"1998","journal-title":"Int J Gynaecol Obstet"},{"issue":"03","key":"ref2","first-page":"483","article-title":"Obstetric outcome after threatened miscarriage with and without a hematoma on ultrasound","volume":"102","author":"J Johns","year":"2003","journal-title":"Obstet Gynecol"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"e111676","DOI":"10.1371\/journal.pone.0111676","article-title":"Symptoms 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Naert","year":"2019","journal-title":"Obstet Gynecol"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1097\/AOG.0000000000003487","article-title":"Association between first-trimester subchorionic hematomas and adverse pregnancy outcomes after 20 weeks of gestation in singleton pregnancies","volume":"134","author":"M N Naert","year":"2019","journal-title":"Obstet Gynecol"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.fertnstert.2016.03.027","article-title":"First-trimester bleeding and twin pregnancy outcomes after in vitro fertilization","volume":"106","author":"J L Eaton","year":"2016","journal-title":"Fertil Steril"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ejogrb.2014.07.014","article-title":"Subchorionic hematoma occurs more frequently in in vitro fertilization pregnancy","volume":"181","author":"K Asato","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"05","key":"ref10","doi-asserted-by":"crossref","first-page":"e150","DOI":"10.1097\/AOG.0000000000002046","article-title":"Committee opinion no 700: methods for estimating the due date","volume":"129","author":"Committee on Obstetric Practice, the American Institute of Ultrasound in Medicine, and the Society for Maternal-Fetal Medicine","year":"2017","journal-title":"Obstet Gynecol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-3401852.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,28]],"date-time":"2021-06-28T22:32:06Z","timestamp":1624919526000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-3401852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,30]]},"references-count":10,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2021,6,28]]},"published-print":{"date-parts":[[2021,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-3401852","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,30]]}}}