{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:43:13Z","timestamp":1740166993791,"version":"3.37.3"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T00:00:00Z","timestamp":1581033600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003The prevalence of deafness is high in Pakistan. Knowledge regarding the clinical features of patients with profound hearing loss will not only help identify the cause but will also help in the strategic planning for public health interventions.<\/jats:p><jats:p>\n          Objective\u2003The present study was conducted to cover in detail the clinical aspects of children with hearing loss, that is, age at presentation, associated deficits and disorders, possible cause of the disease, associated family history, and role of consanguineous marriage.<\/jats:p><jats:p>\n          Methods\u2003The present study was performed from November 2016 to September 2018. All of the patients under 6 years of age with profound bilateral hearing loss who would benefit from cochlear implantation were included in the study. Detailed history was taken. The developmental skills were assessed for all areas, and the patients were scored regarding their motor, manipulative, visual, language, social and self-care skills according to the Schedule of Growing Skills II. Detailed family history was taken from the parents of the affected children. The Statistical Package for the Social Sciences (SPSS) software, version 20.0, was used for the statistical analysis.<\/jats:p><jats:p>\n          Results\u2003The mean age of the children to be treated was 3.2\u2009\u00b1\u2009\u20091.25 years. Most patients (51.5%) had a positive family history of disease. Consanguineous marriage was common; the parents of 76.9% of the patients were first-degree relatives. Most patients (90.8%) had associated language impediments. In total, four (\u01413.07%) patients had global developmental delay.<\/jats:p><jats:p>\n          Conclusion\u2003Consanguineous marriage pattern plays an important role in diseases running in families. Development in these children is strongly linked to their age at the consultation.<\/jats:p>","DOI":"10.1055\/s-0039-3402442","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T23:40:29Z","timestamp":1581118829000},"page":"e457-e461","source":"Crossref","is-referenced-by-count":0,"title":["Precochlear Implant Assessment: Clinical Profile and Family History of Children with Severe Bilateral Prelingual Hearing Loss"],"prefix":"10.1055","volume":"24","author":[{"given":"Syed Hashim","family":"Raza","sequence":"additional","affiliation":[{"name":"Children Hospital, Pakistan Institute of Medical Sciences, Islamabad, Islamabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rehmana","family":"Waris","sequence":"additional","affiliation":[{"name":"Children Hospital, Pakistan Institute of Medical Sciences, Islamabad, Islamabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samina","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Pakistan Institute of Medical Sciences, Islamabad, Islamabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7498-2102","authenticated-orcid":false,"given":"Ramish","family":"Riaz","sequence":"additional","affiliation":[{"name":"Pakistan Institute of Medical Sciences & Rawalpindi Medical College, Islamabad, Islamabad, Pakistan"},{"name":"Atta ur Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Islamabad, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,2,7]]},"reference":[{"volume-title":"WHO global estimates on prevalence of hearing loss","year":"2012","key":"ref1"},{"issue":"06","key":"ref2","first-page":"418","article-title":"Genetic deafness in Pakistani population","volume":"60","author":"G Ali","year":"2010","journal-title":"J Pak Med Assoc"},{"issue":"08","key":"ref3","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1017\/S0022215107007463","article-title":"The Pakistan (Lahore) cochlear implant programme: issues relating to implantation in a developing country","volume":"121","author":"M I Khan","year":"2007","journal-title":"J Laryngol Otol"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"16094","DOI":"10.1038\/nrdp.2016.94","article-title":"Congenital hearing loss","volume":"3","author":"A M Korver","year":"2017","journal-title":"Nat Rev Dis Primers"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1097\/AUD.0b013e31817349d6","article-title":"The contribution of family history to hearing loss in an older population","volume":"29","author":"C M McMahon","year":"2008","journal-title":"Ear Hear"},{"issue":"10","key":"ref6","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.ijporl.2004.05.002","article-title":"Causes of severe to profound deafness in Omani paediatric population","volume":"68","author":"M Al Khabori","year":"2004","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"02","key":"ref7","first-page":"184","article-title":"Screening of Patients for Cochlear Implant Through a Questionnaire Online. Group Profile of Patients Pre-and Peri lingual Not Summoned","volume":"14","author":"A F Leal","year":"2010","journal-title":"Int Arch Otorhinolaryngol"},{"issue":"04","key":"ref8","first-page":"305","article-title":"Profile of patients assessed for cochlear implants","volume":"80","author":"M H Barbosa","year":"2014","journal-title":"Rev Bras Otorrinolaringol (Engl Ed)"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1177\/0194599818797598","article-title":"Assessment and Treatment of Behavioral Disorders in Children with Hearing Loss: A Systematic Review","volume":"160","author":"D Bigler","year":"2019","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"05","key":"ref10","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s10995-017-2287-y","article-title":"What you don't know can hurt you: The risk of language deprivation by impairing sign language development in deaf children","volume":"21","author":"W C Hall","year":"2017","journal-title":"Matern Child Health J"},{"issue":"84","key":"ref11","first-page":"13","article-title":"Effect of Early Intervention on Language Development in Hearing-Impaired Children","volume":"28","author":"E Shojaei","year":"2016","journal-title":"Iran J Otorhinolaryngol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.puhe.2016.12.019","article-title":"Causes of deafness in the Punjab region of Pakistan and the role of consanguinity","volume":"145","author":"S Ullah","year":"2017","journal-title":"Public Health"},{"key":"ref13","first-page":"6","volume-title":"Childhood Hearing Loss: Strategies for prevention and care","author":"E Krug","year":"2016"},{"issue":"02","key":"ref14","first-page":"33","article-title":"Special Education and Deaf Children in Pakistan: An Overview","volume":"22","author":"B Akram","year":"2012","journal-title":"Journal of Elementary Education."},{"key":"ref15","first-page":"1","article-title":"The Effect of Age of Cochlear Implantation on Speech Intelligibility to Others","volume":"22","author":"E Schafer","year":"2016","journal-title":"JEPRA"}],"container-title":["International Archives of Otorhinolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-3402442.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T22:51:17Z","timestamp":1603234277000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-3402442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,7]]},"references-count":15,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2020,10,20]]},"published-print":{"date-parts":[[2020,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-3402442","relation":{},"ISSN":["1809-9777","1809-4864"],"issn-type":[{"type":"print","value":"1809-9777"},{"type":"electronic","value":"1809-4864"}],"subject":[],"published":{"date-parts":[[2020,2,7]]}}}