{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:38:25Z","timestamp":1789681105975,"version":"4.0.1"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"S 03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003This study proposes to present reference parameters for trigeminal (V) and facial (VII) cranial nerves (CNs)-triggered electromyography (tEMG) during endoscopic endonasal approach (EEA) skull base surgeries to allow more precise and accurate mapping of these CNs.<\/jats:p><jats:p>\n          Study Design\u2003We retrospectively reviewed EEA procedures performed at the University of Pittsburgh Medical Center between 2009 and 2015. tEMG recorded in response to stimulation of CN V and VII was analyzed. Analysis of tEMG waveforms included latencies and amplitudes. Medical records were reviewed to determine the presence of perioperative neurologic deficits.<\/jats:p><jats:p>\n          Results\u2003A total of 28 patients were included. tEMG from 34 CNs (22\u2009V and 12 VII) were analyzed. For CN V, the average onset latency was 2.9\u2009\u00b1\u20091.1\u2009ms and peak-to-peak amplitude was 525\u2009\u00b1\u2009436.94\u2009\u03bcV (n\u2009=\u200922). For CN VII, the average onset latency and peak-to-peak amplitude were 5.1\u2009\u00b1\u20091.43\u2009ms and 315\u2009\u00b1\u2009352.58\u2009\u03bcV for the orbicularis oculi distribution (n\u2009=\u200909), 5.9\u2009\u00b1\u20090.67\u2009ms and 517\u2009\u00b1\u2009489.07\u2009\u03bcV on orbicularis oris (n\u2009=\u200908), and 5.3\u2009\u00b1\u20090.98\u2009ms 303.1\u2009\u00b1\u2009215.3\u2009\u03bcV on mentalis (n\u2009=\u200907), respectively.<\/jats:p><jats:p>\n          Conclusion\u2003Our data support the notion that onset latency may be a feasible parameter in the differentiation between the CN V and VII during the crosstalk phenomenon in EEA surgeries but the particularities of this type of procedure should be taken into consideration. A prospective analysis with a larger data set is necessary.<\/jats:p>","DOI":"10.1055\/s-0040-1701649","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T21:11:11Z","timestamp":1585689071000},"page":"e342-e348","source":"Crossref","is-referenced-by-count":4,"special_numbering":"S","title":["Neurophysiological Characteristics of Cranial Nerves V- and VII-Triggered EMG in Endoscopic Endonasal Approach Skull Base Surgery"],"prefix":"10.1055","volume":"82","author":[{"given":"Carla J.A.","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Sherer","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Anetakis","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald J.","family":"Crammond","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Balzer","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parthasarathy D.","family":"Thirumala","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of 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neurophysiological monitoring during resection of infratentorial lesions: the surgeon's view","volume":"126","author":"P J Slotty","year":"2017","journal-title":"J Neurosurg"},{"key":"ref4","first-page":"1751245","article-title":"Intraoperative neurophysiological monitoring for endoscopic endonasal approaches to the skull base: a technical guide","volume":"2016","author":"H Singh","year":"2016","journal-title":"Scientifica (Cairo)"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/mus.10506","article-title":"Intraoperative cranial nerve monitoring","volume":"29","author":"C M Harper","year":"2004","journal-title":"Muscle Nerve"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.17116\/neiro201680335-49","article-title":"Neurophysiological identification of the cranial nerves in endoscopic endonasal surgery of skull base tumors [in Russian]","volume":"80","author":"A N 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for vestibular schwannoma","volume":"106","author":"J Prell","year":"2007","journal-title":"J Neurosurg"},{"issue":"02","key":"ref10","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.nec.2008.02.011","article-title":"Intraoperative monitoring of facial and cochlear nerves during acoustic neuroma surgery. 1992","volume":"19","author":"C D Yingling","year":"2008","journal-title":"Neurosurg Clin N Am"},{"issue":"06","key":"ref11","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1046\/j.1365-2273.1999.00287.x","article-title":"Prediction of postoperative facial nerve function in acoustic neuroma surgery","volume":"24","author":"J E Fenton","year":"1999","journal-title":"Clin Otolaryngol Allied Sci"},{"issue":"02","key":"ref12","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/00129492-200503000-00025","article-title":"Prediction of long-term facial nerve outcomes with intraoperative nerve monitoring","volume":"26","author":"B Isaacson","year":"2005","journal-title":"Otol Neurotol"},{"issue":"03","key":"ref13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1055\/s-2008-1057002","article-title":"Prediction of facial nerve function after surgery for cerebellopontine angle tumors: use of a facial nerve stimulator and monitor","volume":"1","author":"P J Kirkpatrick","year":"1991","journal-title":"Skull Base Surg"},{"issue":"02","key":"ref14","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1097\/MAO.0b013e3181be6228","article-title":"Intraoperative electromyography and surgical observations as predictive factors of facial nerve outcome in vestibular schwannoma surgery","volume":"31","author":"I Bernat","year":"2010","journal-title":"Otol Neurotol"},{"issue":"01","key":"ref15","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/0090-3019(91)90126-T","article-title":"Facial nerve monitoring by monopolar low constant current stimulation during acoustic neurinoma surgery","volume":"36","author":"T Yokoyama","year":"1991","journal-title":"Surg Neurol"},{"issue":"03","key":"ref16","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1055\/s-2008-1058931","article-title":"Intraoperative monitoring of motor cranial nerves in skull base surgery","volume":"5","author":"J Maurer","year":"1995","journal-title":"Skull Base Surg"},{"issue":"01","key":"ref17","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S1042-3680(18)30833-7","article-title":"Acoustic neuroma","volume":"1","author":"R K Jackler","year":"1990","journal-title":"Neurosurg Clin N Am"},{"issue":"02","key":"ref18","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/S0303-8467(01)00115-9","article-title":"Intra-operative electromyographic monitoring of the lower cranial motor nerves (LCN IX-XII) in skull base surgery","volume":"103","author":"H-P Schlake","year":"2001","journal-title":"Clin Neurol Neurosurg"},{"key":"ref19","first-page":"131","volume-title":"Regional monitoring of the lower (ninth through twelfth) cranial nerves","author":"M J Lanser","year":"1991"},{"issue":"06","key":"ref20","doi-asserted-by":"crossref","first-page":"e271","DOI":"10.1016\/j.wneu.2011.09.026","article-title":"Facial nerve monitoring during cerebellopontine angle and skull base tumor surgery: a systematic review from description to current success on function prediction","volume":"80","author":"M A Acioly","year":"2013","journal-title":"World Neurosurg"},{"issue":"06","key":"ref21","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/WNP.0b013e318241de1a","article-title":"Neurophysiologic intraoperative monitoring of trigeminal and facial nerves","volume":"28","author":"R E Minahan","year":"2011","journal-title":"J Clin Neurophysiol"},{"issue":"05","key":"ref22","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1097\/MAO.0b013e318171975e","article-title":"Optimal placement of 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