{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T03:56:53Z","timestamp":1648785413404},"reference-count":6,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T00:00:00Z","timestamp":1596153600000},"content-version":"vor","delay-in-days":121,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aorta (Stamford)"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Despite improvements in operative techniques, open thoracoabdominal aortic aneurysm (TAAA) repair is complex and characterized by high mortality and morbidity rate. Less invasive techniques have been developed since 2005 for the treatment of TAAA. Unfortunately, many of these devices require custom fabrication, resulting in delay of many weeks until treatment can be delivered but crucial in critical emergency cases. We present a novel hybrid endovascular and surgical prosthesis, which was tested on five pigs, with the aim of reducing the barrier issues of endovascular therapy in such particular cases.<\/jats:p><jats:p>\n          Methods\u2003The principal characteristic of the proposed hybrid endovascular prosthesis is to combine a proximal and distal stented zones and, in between, a classical surgical blood tied Dacron prosthesis. The device was tested in five pigs where feasibility of implantation and acute postoperative outcomes were evaluated, including bleeding, bowel ischemia, renal function, and peripheral blood perfusion.<\/jats:p><jats:p>\n          Results\u2003In all cases, following laparotomy, the endoprosthesis was successfully implanted under fluoroscopy and the surgical prosthesis zone could be easily detected by the radio-opaque markers. No major bleeding or cardiac events occurred throughout preparation and implantation. One hour after prosthesis implantation and surgical anastomoses of all vessels were completed, normal urine output was registered, and no acidosis was detected.<\/jats:p><jats:p>\n          Conclusions\u2003This novel graft has shown ease of endoprosthesis and visceral vessels implantation without the need of thoracotomy or extracorporeal circulation and may be useful in an emergency setting or high risk and complex anatomy TAAA unsuitable for traditional endovascular aneurysm repair, or to avoid an excess waiting time for a \u201ccustom made\u201d prosthesis. The great adaptability of this \u201chybrid\u201d prosthesis in complex anatomy for the majority of TAAA could be important in high-risk patients and in some difficult situations, such as a high risk of imminent rupture.<\/jats:p>","DOI":"10.1055\/s-0040-1702143","type":"journal-article","created":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T22:31:20Z","timestamp":1596234680000},"page":"025-028","source":"Crossref","is-referenced-by-count":0,"title":["A Novel Endosurgical Prosthesis to Treat Thoracoabdominal Aortic Aneurysm in Complex Anatomy or Emergency Settings"],"prefix":"10.1055","volume":"08","author":[{"given":"Guglielmo","family":"Saitto","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Istituto di ricovero e cura a carattere scientifico, San Donato Milanese Hospital, San Donato Milanese, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Scafuri","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Tor Vergata University of Rome, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saimir","family":"Kuci","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Reanimation Mother Teresa University, Tirana, Albania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred","family":"Ibrahimi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Reanimation Mother Teresa University, Tirana, Albania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Zeitani","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences and Specialized Surgery, University of Ferrara, Ferrara, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,7,31]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"S134","DOI":"10.1016\/j.jtcvs.2014.09.038","article-title":"Contemporary outcomes of open thoracoabdominal aortic aneurysm repair in octogenarians","volume":"149","author":"M Aftab","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.jvs.2006.06.013","article-title":"Hybrid approach to complex thoracic aortic aneurysms in high-risk patients: surgical challenges and clinical outcomes","volume":"44","author":"W Zhou","year":"2006","journal-title":"J Vasc Surg"},{"issue":"03","key":"ref3","first-page":"267","article-title":"Combined open and endovascular treatment of thoracoabdominal aortic pathologies: a systematic review and meta-analysis","volume":"1","author":"K G Moulakakis","year":"2012","journal-title":"Ann Cardiothorac Surg"},{"issue":"04","key":"ref4","first-page":"393","article-title":"Possible graft-related complications in visceral debranching for hybrid B dissection repair","volume":"3","author":"R Chiesa","year":"2014","journal-title":"Ann Cardiothorac Surg"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1016\/j.jtcvs.2016.10.008","article-title":"Endovascular repair of thoracoabdominal aortic aneurysms using fenestrated and branched endografts","volume":"153","author":"G S Oderich","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"07","key":"ref9","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1055\/s-0033-1333895","article-title":"Hybrid approach to treat total thoracic aortic aneurysm in a patient undergoing emergency surgery for descending aortic rupture","volume":"61","author":"J Zeitani","year":"2013","journal-title":"Thorac Cardiovasc Surg"}],"container-title":["AORTA"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1702143.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T02:07:31Z","timestamp":1598321251000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1702143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":6,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2020,7,31]]},"published-print":{"date-parts":[[2020,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1702143","relation":{},"ISSN":["2325-4637"],"issn-type":[{"value":"2325-4637","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4]]}}}