{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:46:59Z","timestamp":1787618819578,"version":"build-2736575974"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Thromb Hemost"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This article explores the application of viscoelastic tests (VETs) in trauma-induced coagulopathy and trauma resuscitation. We describe the advantages of VETs over conventional coagulation tests in the trauma setting and refer to previous disciplines in which VET use has reduced blood product utilization, guided prohemostatic agents, and improved clinical outcomes such as the mortality of critically bleeding patients. We describe different VETs and provide guidance for blood component therapy and prohemostatic therapy based on specific VET parameters. Because the two most commonly used VET systems, rotational thromboelastometry and thromboelastography, use different activators and have different terminologies, this practical narrative review will directly compare and contrast these two VETs to help the clinician easily interpret either and use the interpretation to determine hemostatic integrity in the bleeding trauma patient. Finally, we anticipate the future of new viscoelastic technologies that can be used in this setting.<\/jats:p>","DOI":"10.1055\/s-0040-1702171","type":"journal-article","created":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T23:38:37Z","timestamp":1583969917000},"page":"134-146","source":"Crossref","is-referenced-by-count":47,"title":["Diagnosis and Treatment of Trauma-Induced Coagulopathy by Viscoelastography"],"prefix":"10.1055","volume":"46","author":[{"given":"Jan","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Haemonetics Corporation, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Walsh","sequence":"additional","affiliation":[{"name":"Saint Joseph Regional Medical Center, Mishawaka, Indiana"},{"name":"Memorial Hospital Trauma Center, South Bend, Indiana"},{"name":"W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Grisoli","sequence":"additional","affiliation":[{"name":"Indiana University School of Medicine\u2014South Bend Campus, Notre Dame, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony V.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Saint Joseph Regional Medical Center, Mishawaka, Indiana"},{"name":"Memorial Hospital Trauma Center, South Bend, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal","family":"Shariff","sequence":"additional","affiliation":[{"name":"Indiana University School of Medicine\u2014South Bend Campus, Notre Dame, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross","family":"McCauley","sequence":"additional","affiliation":[{"name":"Indiana University School of Medicine\u2014South Bend Campus, Notre Dame, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefani","family":"Vande Lune","sequence":"additional","affiliation":[{"name":"Indiana University School of Medicine\u2014South Bend Campus, Notre Dame, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuha","family":"Zackariya","sequence":"additional","affiliation":[{"name":"Saint Joseph Regional Medical Center, Mishawaka, Indiana"},{"name":"Memorial Hospital Trauma Center, South Bend, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivani","family":"Patel","sequence":"additional","affiliation":[{"name":"Saint Joseph Regional Medical Center, Mishawaka, Indiana"},{"name":"Memorial Hospital Trauma Center, South Bend, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Farrell","sequence":"additional","affiliation":[{"name":"Department of Trauma, Surgery, and Critical Care Medicine, Christiana Care Health Services, Wilmington, Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherry","family":"Sixta","sequence":"additional","affiliation":[{"name":"Department of Trauma, Surgery, and Critical Care Medicine, Christiana Care Health Services, Wilmington, Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"March","sequence":"additional","affiliation":[{"name":"Saint Joseph Regional Medical Center, Mishawaka, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Evans","sequence":"additional","affiliation":[{"name":"Saint Joseph Regional Medical Center, Mishawaka, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Tracy","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Southern Illinois University School of Medicine, Springfield, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Campello","sequence":"additional","affiliation":[{"name":"Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, Padua University Hospital, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ecaterina","family":"Sc\u0103rl\u0103tescu","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Fundeni Clinical Institute, Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Agostini","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Transfusion Medicine Cesena\/Forl\u00ec and Blood Establishment, Azienda USL della Romagna, Romagna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Dias","sequence":"additional","affiliation":[{"name":"Haemonetics S. A., Signy, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Greve","sequence":"additional","affiliation":[{"name":"Haemonetics Corporation, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Thomas","sequence":"additional","affiliation":[{"name":"Memorial Hospital Trauma Center, South Bend, Indiana"},{"name":"W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,3,11]]},"container-title":["Seminars in Thrombosis and Hemostasis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1702171.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T23:38:40Z","timestamp":1583969920000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1702171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2020,3,11]]},"published-print":{"date-parts":[[2020,3]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1702171","relation":{},"ISSN":["0094-6176","1098-9064"],"issn-type":[{"value":"0094-6176","type":"print"},{"value":"1098-9064","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3]]}}}