{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:58Z","timestamp":1740126838400,"version":"3.37.3"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"06","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81672869"],"award-info":[{"award-number":["81672869"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Jiangsu Provincial Medical Outstanding Talent"},{"DOI":"10.13039\/501100013059","name":"Jiangsu Provincial Medical Youth Talent","doi-asserted-by":"crossref","award":["QNRC2016657"],"award-info":[{"award-number":["QNRC2016657"]}],"id":[{"id":"10.13039\/501100013059","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Jiangsu Cancer Hospital","award":["YC201814"],"award-info":[{"award-number":["YC201814"]}]},{"name":"\u201c333\u201d talent project","award":["BRA2019325"],"award-info":[{"award-number":["BRA2019325"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The localization of small pulmonary nodules (SPNs) during video-assisted thoracoscopic surgery (VATS) is challenging thoracic surgeon, especially in patients with severe pleural adhesion or visceral pleura pigmentation due to low success rate and future conversion to thoracotomy. This study aims to compare the efficacy and safety between modified microcoil and methylene blue in preoperative localization of small nodules, particularly patients with severe pleural adhesion or visceral pleura pigmentation.<\/jats:p><jats:p>\n          Materials and Methods\u2003From January 2018 to February 2019 in our institute, 342 patients who underwent computed tomography-guided localization of SPN were recruited in this retrospective cohort study and divided into the modified microcoil group (n\u2009=\u2009239) and the methylene blue group (n\u2009=\u2009103) according to the localization method. Clinical characteristics and perioperative complications were collected to analyze.<\/jats:p><jats:p>\n          Results\u2003All SPNs were successfully marked in both groups. Location-related complications, the duration of localization procedure, and the length of hospital stay were not different between the two groups. The operation time of modified microcoil and the duration of removal of nodule in operation were both shorter than the methylene blue (p\u2009=\u20090.014 and p\u2009=\u20090.047). The analysis stratified by gender showed that similar results were found in male patients (p\u2009=\u20090.01 and p\u2009=\u20090.00), while in female patients, no significant difference was found. Additionally, in senior patients (older than 60 years), the operation time in modified microcoil groups was less than methylene blue group (p\u2009=\u20090.024).<\/jats:p><jats:p>\n          Conclusion\u2003Compared with methylene blue, modified microcoil achieved a shorter operation time of removal of nodule in VATS, especially for patients with pleural adhesion and the pigmentation of the lung surface as well as the male patients and the patients older than 60 years.<\/jats:p>","DOI":"10.1055\/s-0040-1708471","type":"journal-article","created":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T23:20:18Z","timestamp":1592608818000},"page":"533-539","source":"Crossref","is-referenced-by-count":6,"title":["Application of Modified Tailed Microcoil in Preoperative Localization of Small Pulmonary Nodules: A Retrospective Study"],"prefix":"10.1055","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3727-1704","authenticated-orcid":false,"given":"Saisai","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaichao","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binhui","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Jiangsu Cancer Hospital, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,6,19]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1148\/radiol.2333031018","article-title":"Malignant versus benign nodules at CT screening for lung cancer: comparison of thin-section CT findings","volume":"233","author":"F Li","year":"2004","journal-title":"Radiology"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"108S","DOI":"10.1378\/chest.07-1353","article-title":"Evaluation of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition)","volume":"132","author":"K Gould Michael","year":"2007","journal-title":"Chest"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s00595-018-1742-8","article-title":"Advances in techniques for identifying small pulmonary nodules","volume":"49","author":"J Nakajima","year":"2019","journal-title":"Surg Today"},{"issue":"08","key":"ref4","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1007\/s00464-007-9720-z","article-title":"Video-assisted thoracic surgery (VATS) lobectomy: 13 years' experience","volume":"22","author":"M Congregado","year":"2008","journal-title":"Surg Endosc"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1378\/chest.115.2.563","article-title":"Video-assisted thoracoscopic surgery for small indeterminate pulmonary nodules: indications for preoperative marking","volume":"115","author":"K Suzuki","year":"1999","journal-title":"Chest"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.chest.2016.09.017","article-title":"Comparative effectiveness and safety of preoperative lung localization for pulmonary nodules: a systematic review and meta-analysis","volume":"151","author":"C H Park","year":"2017","journal-title":"Chest"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"e14029","DOI":"10.1097\/MD.0000000000014029","article-title":"Application of intrapulmonary wire combined with intrapleural fibrin glue in preoperative localization of small pulmonary nodules","volume":"98","author":"W H Zhang","year":"2019","journal-title":"Medicine (Baltimore)"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1097\/00004728-200103000-00029","article-title":"Localization of pulmonary nodules using suture-ligated microcoils","volume":"25","author":"J P Reinschmidt","year":"2001","journal-title":"J Comput Assist Tomogr"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1148\/radiol.2019181674","article-title":"CT-guided microcoil pulmonary nodule localization prior to video-assisted thoracoscopic surgery: diagnostic utility and recurrence-free survival","volume":"291","author":"J CL Rodrigues","year":"2019","journal-title":"Radiology"},{"issue":"03","key":"ref10","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1378\/chest.114.3.704","article-title":"Percutaneous transthoracic needle aspiration biopsy: a comprehensive review of its current role in the diagnosis and treatment of lung tumors","volume":"114","author":"R C Larscheid","year":"1998","journal-title":"Chest"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.jss.2017.12.020","article-title":"Analysis of factors affecting successful microcoil localization for pulmonary nodules","volume":"224","author":"X Sui","year":"2018","journal-title":"J Surg Res"},{"issue":"05","key":"ref12","doi-asserted-by":"crossref","first-page":"2676","DOI":"10.21037\/jtd.2018.04.87","article-title":"High-resolution computed tomography features and CT-guided microcoil localization of subcentimeter pulmonary ground-glass opacities: radiological processing prior to video-assisted thoracoscopic surgery","volume":"10","author":"Z X Wang","year":"2018","journal-title":"J Thorac Dis"},{"issue":"01","key":"ref13","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jtcvs.2014.08.055","article-title":"Preoperative computed tomography-guided microcoil localization of small peripheral pulmonary nodules: a prospective randomized controlled trial","volume":"149","author":"R J Finley","year":"2015","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"03","key":"ref14","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/01.sla.0000137132.01881.57","article-title":"Peripheral lung nodules: fluoroscopically guided video-assisted thoracoscopic resection after computed tomography-guided localization using platinum microcoils","volume":"240","author":"T I Powell","year":"2004","journal-title":"Ann Surg"},{"issue":"02","key":"ref15","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1148\/radiol.2502080442","article-title":"Lung nodules: CT-guided placement of microcoils to direct video-assisted thoracoscopic surgical resection","volume":"250","author":"J R Mayo","year":"2009","journal-title":"Radiology"},{"issue":"08","key":"ref16","doi-asserted-by":"crossref","first-page":"4036","DOI":"10.1007\/s00330-018-5939-4","article-title":"Comparison between the application of microcoil and hookwire for localizing pulmonary nodules","volume":"29","author":"L Hu","year":"2019","journal-title":"Eur Radiol"},{"issue":"06","key":"ref17","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1177\/0284185113506136","article-title":"Novel CT-guided coil localization of peripheral pulmonary nodules prior to video-assisted thoracoscopic surgery: a pilot study","volume":"55","author":"L Liu","year":"2014","journal-title":"Acta Radiol"},{"issue":"08","key":"ref18","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.21037\/jtd.2016.06.74","article-title":"CT-guided microcoil VATS resection of lung nodules: a single-centre experience and review of the literature","volume":"8","author":"L L Donahoe","year":"2016","journal-title":"J Thorac Dis"},{"issue":"01","key":"ref19","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ijrobp.2010.04.037","article-title":"High retention and safety of percutaneously implanted endovascular embolization coils as fiducial markers for image-guided stereotactic ablative radiotherapy of pulmonary tumors","volume":"81","author":"J C Hong","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"02","key":"ref20","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.jtcvs.2016.04.052","article-title":"Computed tomography-guided patent blue vital dye localization of pulmonary nodules in uniportal thoracoscopy","volume":"152","author":"M W Lin","year":"2016","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1708471.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T22:33:41Z","timestamp":1600382021000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1708471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,19]]},"references-count":20,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2020,9,17]]},"published-print":{"date-parts":[[2020,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1708471","relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"type":"print","value":"0171-6425"},{"type":"electronic","value":"1439-1902"}],"subject":[],"published":{"date-parts":[[2020,6,19]]}}}