{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T06:56:26Z","timestamp":1793256986997,"version":"4.5.0"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"S 01","funder":[{"name":"Science and Technology Foundation","award":["W2016196"],"award-info":[{"award-number":["W2016196"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Objective\u2003In this study, our objective was to explore the relevant influencing factors of neonatal hypoxic-ischemic encephalopathy (HIE) in Southern China and provide scientific basis for improving the quality of life for neonates.<\/jats:p>\n                  <jats:p>Study Design\u2003A retrospective analysis of 306 cases with HIE neonates who were admitted during April 2015 to October 2017 was conducted. A total of 306 non-HIE patients admitted to the same hospital during the same period were also included as controls. The basic clinical characteristics were analyzed, and the risk factors for HIE were assessed by logistic regression analysis.<\/jats:p>\n                  <jats:p>Results\u2003Univariate analysis showed that the differences in medicals during pregnancy, placenta previa, fetal distress during labor, cesarean section, amniotic fluid contamination, abnormal labor stage, and Apgar showed significantly different in the case group and the control group (p\u2009&lt;\u20090.05). The multivariate logistic regression analysis revealed that the placenta previa, medicals during pregnancy, fetal distress, abnormal labor stage, Apgar's score, amniotic fluid contamination, and cesarean section were independent risk factors for HIE.<\/jats:p>\n                  <jats:p>Conclusion\u2003The placenta previa, medicals during pregnancy, fetal distress, and abnormal labor stage can increase the risk of HIE. Early detection, early diagnosis, and treatment might make great achievement in improving the life quality of HIE neonates.<\/jats:p>","DOI":"10.1055\/s-0040-1708884","type":"journal-article","created":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T19:43:02Z","timestamp":1585338182000},"page":"e182-e186","source":"Crossref","is-referenced-by-count":8,"special_numbering":"S","title":["Perinatal Risk Factors Influencing Neonatal Hypoxic Ischemic Encephalopathy in Southern China: A Case\u2013Control Study"],"prefix":"10.1055","volume":"38","author":[{"given":"Junrong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Wenling Maternal and Child Health Care Hospital, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enfu","family":"Tao","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Wenling Maternal and Child Health Care Hospital, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaojun","family":"Mo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Wenling Maternal and Child Health Care Hospital, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weimin","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Wenling Maternal and Child Health Care Hospital, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhui","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Wenling Maternal and Child Health Care Hospital, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Taizhou Women's and Children's Hospital, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5862-4620","authenticated-orcid":false,"given":"Changhua","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Wenling Maternal and Child Health Care Hospital, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haixiao","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Taizhou Women's and Children's Hospital, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,3,27]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.earlhumdev.2010.05.010","article-title":"Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy","volume":"86","author":"J J Kurinczuk","year":"2010","journal-title":"Early Hum 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