{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:47:08Z","timestamp":1790567228883,"version":"4.1.0"},"reference-count":16,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"05","license":[{"start":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T00:00:00Z","timestamp":1590710400000},"content-version":"vor","delay-in-days":28,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003To assess maternal and perinatal outcomes of pregnancies in women with chronic hypertension (CH).<\/jats:p><jats:p>\n          Methods\u2003Retrospective cohort of women with CH followed at a referral center for a 5 year period (2012\u20132017). Data were obtained from medical charts review and described as means and frequencies, and a Poisson regression was performed to identify factors independently associated to the occurrence of superimposed pre-eclampsia (sPE).<\/jats:p><jats:p>\n          Results\u2003A total of 385 women were included in the present study; the majority were\u2009&gt;\u2009than 30 years old, multiparous, mostly white and obese before pregnancy. One third had pre-eclampsia (PE) in a previous pregnancy and 17% of them had organ damage associated with hypertension, mainly kidney dysfunction. A total of 85% of the patients used aspirin and calcium carbonate for pre-eclampsia prophylaxis and our frequency of sPE was 40%, with an early onset (32.98\u2009\u00b1\u20096.14 weeks). Of those, 40% had severe features of PE, including 5 cases of HELLP syndrome; however, no cases of eclampsia or maternal death were reported. C-section incidence was high, gestational age at birth was 36 weeks, and nearly a third (115 cases) of newborns had complications at birth One third of the women remained using antihypertensive drugs after pregnancy.<\/jats:p><jats:p>\n          Conclusion\u2003Chronic hypertension is related with the high occurrence of PE, C-sections, prematurity and neonatal complications. Close surveillance and multidisciplinary care are important for early diagnosis of complications.<\/jats:p>","DOI":"10.1055\/s-0040-1709190","type":"journal-article","created":{"date-parts":[[2020,6,2]],"date-time":"2020-06-02T05:43:35Z","timestamp":1591076615000},"page":"248-254","source":"Crossref","is-referenced-by-count":16,"title":["Maternal and Perinatal Outcomes of Pregnancies Complicated by Chronic Hypertension Followed at a Referral Hospital"],"prefix":"10.61622","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7289-0191","authenticated-orcid":false,"given":"Gabriela Pravatta","family":"Rezende","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5412-7264","authenticated-orcid":false,"given":"Laura","family":"Casagrande","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3648-6159","authenticated-orcid":false,"given":"Jos\u00e9 Paulo Siqueira","family":"Guida","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6000-9707","authenticated-orcid":false,"given":"Mary Angela","family":"Parpinelli","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4335-0337","authenticated-orcid":false,"given":"Fernanda Garanhani","family":"Surita","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8280-3234","authenticated-orcid":false,"given":"Maria Laura","family":"Costa","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2020,5,29]]},"reference":[{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.5123\/S1679-49742015000200012","article-title":"Preval\u00eancia de hipertens\u00e3o arterial autorreferida na popula\u00e7\u00e3o brasileira: an\u00e1lise da Pesquisa Nacional de Sa\u00fade, 2013","volume":"24","author":"S SA Andrade","year":"2015","journal-title":"Epidemiol Serv Saude"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1161\/HYPERTENSIONAHA.117.10803","article-title":"Hypertensive 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