{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:53:35Z","timestamp":1783464815525,"version":"3.55.0"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Acute aortic dissection Type A (AADA) is still associated with a high mortality rate and frequent postoperative complications. This study was designed to evaluate the risk factors for mortality in AADA patients.<\/jats:p><jats:p>\n          Patients and Methods\u2003This retrospective analysis included 344 consecutive patients who underwent surgery for AADA in moderate hypothermic circulatory arrest (20\u201324\u00b0C nasopharyngeal) between 2001 and 2016.<\/jats:p><jats:p>\n          Results\u2003The 30-day mortality rate was 18%. Nonsurvivors were significantly older (65.7\u2009\u00b1\u200912.0 years vs. 62.0\u2009\u00b1\u200912.5 years; p\u2009=\u20090.034) with significantly higher Euro-score II [15.4% (6.6; 23.0) vs. 4.63% (2.78; 9.88); p\u2009&lt;\u20090.001)]. Intraoperatively, survivors had statistically shorter cardiopulmonary bypass times [163 (134; 206) vs. 198\u2009min (150; 245); p\u2009=\u20090.001]. However, the hypothermic circulatory arrest time was similar between both groups. Postoperatively, the incidence of acute kidney injury (AKI) (55.9 vs. 15.2%; p\u2009&lt;\u20090.001), stroke (27.9 vs. 12.1%; p\u2009=\u20090.002) and sepsis (18.0 vs. 2.1%; p\u2009&lt;\u20090.001) were significantly higher among nonsurvivors. The multi-variable logistic regression confirmed that older age, previous cardiac surgery, preoperative cardiopulmonary resuscitation (CPR), blood transfusion and postoperative acute kidney injury (AKI) were independent risk factors for mortality.<\/jats:p><jats:p>\n          Conclusion\u2003Our analysis suggested that the reason for mortality was multifactorial, especially age, previous cardiac surgery, CPR, transfusion, as well as postoperative AKI were considered risk factors for mortality.<\/jats:p>","DOI":"10.1055\/s-0040-1710002","type":"journal-article","created":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T23:20:18Z","timestamp":1592608818000},"page":"322-328","source":"Crossref","is-referenced-by-count":16,"title":["Risk Factors for Mortality in Acute Aortic Dissection Type A: A Centre Experience Over 15 Years"],"prefix":"10.1055","volume":"69","author":[{"given":"Mohamed","family":"Salem","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4228-7164","authenticated-orcid":false,"given":"Christine","family":"Friedrich","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Thiem","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Huenges","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Puehler","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Cremer","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assad","family":"Haneya","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Hospital Schleswig-Holstein Campus Kiel, Kiel, 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