{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T22:52:17Z","timestamp":1781563937550,"version":"3.54.5"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81972086"],"award-info":[{"award-number":["81972086"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81672196"],"award-info":[{"award-number":["81672196"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["51971222"],"award-info":[{"award-number":["51971222"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Shanghai \u201cRising Stars of Medical Talent\u201d Youth Development Program"},{"name":"National Key Research and Development Project"},{"name":"Key Project of Shanghai Science and Technology Commission","award":["19411962800"],"award-info":[{"award-number":["19411962800"]}]},{"name":"Shanghai Municipal Education Commission\u2014Gaofeng Clinical Medicine Grant Support","award":["20161423"],"award-info":[{"award-number":["20161423"]}]},{"name":"Clinical Scientific Innovation and Cultivation Fund of Renji Hospital Affiliated School of Medicine, Shanghai Jiaotong University","award":["PY2018-I-02"],"award-info":[{"award-number":["PY2018-I-02"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Knee Surg"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this study was to develop a predictive model for length of stay (LOS) after total knee arthroplasty (TKA). Between 2013 and 2014, 1,826 patients who underwent TKA from a single Singapore center were enrolled in the study after qualification. Demographics of patients with normal and prolonged LOS were analyzed. The risk variables that could affect LOS were identified by univariate analysis. Predictive models for LOS after TKA by logistic regression or machine learning were constructed and compared. The univariate analysis showed that age, American Society of Anesthesiologist level, diabetes, ischemic heart disease, congestive heart failure, general anesthesia, and operation duration were risk factors that could affect LOS (p\u2009&lt;\u20090.05). Comparing with logistic regression models, the machine learning model with all variables was the best model to predict LOS after TKA, of whose area of operator characteristic curve was 0.738. Machine learning algorithms improved the predictive performance of LOS prediction models for TKA patients.<\/jats:p>","DOI":"10.1055\/s-0040-1710573","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T23:43:17Z","timestamp":1591659797000},"page":"007-014","source":"Crossref","is-referenced-by-count":30,"title":["Construction and Comparison of Predictive Models for Length of Stay after Total Knee Arthroplasty: Regression Model and Machine Learning Analysis Based on 1,826 Cases in a Single Singapore Center"],"prefix":"10.1055","volume":"35","author":[{"given":"Hui","family":"Li","sequence":"first","affiliation":[{"name":"Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juyang","family":"Jiao","sequence":"first","affiliation":[{"name":"Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shutao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haozheng","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhua","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Yue","sequence":"additional","affiliation":[{"name":"Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,6,8]]},"reference":[{"issue":"17","key":"ref1","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.2106\/JBJS.N.01141","article-title":"Prevalence of total hip and knee replacement in the United States","volume":"97","author":"H Maradit Kremers","year":"2015","journal-title":"J Bone Joint Surg Am"},{"issue":"08","key":"ref2","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s00402-012-1528-1","article-title":"Pathway-controlled fast-track rehabilitation after total knee arthroplasty: a randomized prospective clinical study evaluating the recovery pattern, drug consumption, and length of stay","volume":"132","author":"A den Hertog","year":"2012","journal-title":"Arch Orthop Trauma Surg"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s00402-011-1396-0","article-title":"Reduced length of stay following hip and knee arthroplasty in Denmark 2000-2009: from research to implementation","volume":"132","author":"H Husted","year":"2012","journal-title":"Arch Orthop Trauma Surg"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s11999-010-1486-2","article-title":"Hospital economics of primary total knee arthroplasty at a teaching hospital","volume":"469","author":"W L Healy","year":"2011","journal-title":"Clin Orthop Relat Res"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s11420-010-9164-1","article-title":"A multimodal clinical pathway can reduce length of stay after total knee arthroplasty","volume":"7","author":"O Ayalon","year":"2011","journal-title":"HSS J"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1054\/arth.2003.50030","article-title":"Effectiveness of clinical pathways for total knee and total hip arthroplasty: literature review","volume":"18","author":"S Kim","year":"2003","journal-title":"J Arthroplasty"},{"issue":"24","key":"ref7","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1001\/jama.1993.03510240069035","article-title":"A new Simplified Acute Physiology Score (SAPS II) based on a European\/North American multicenter study","volume":"270","author":"J R Le Gall","year":"1993","journal-title":"JAMA"},{"issue":"07","key":"ref8","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1513\/AnnalsATS.201405-185AS","article-title":"What's so different about big data? A primer for clinicians trained to think epidemiologically","volume":"11","author":"T J Iwashyna","year":"2014","journal-title":"Ann Am Thorac Soc"},{"issue":"02","key":"ref9","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/CCM.0000000000001571","article-title":"Multicenter comparison of machine learning methods and conventional regression for predicting clinical deterioration on the wards","volume":"44","author":"M M Churpek","year":"2016","journal-title":"Crit Care Med"},{"issue":"07","key":"ref10","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1097\/CCM.0000000000003123","article-title":"The development of a machine learning inpatient acute kidney injury prediction model","volume":"46","author":"J L Koyner","year":"2018","journal-title":"Crit Care Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.neunet.2013.11.002","article-title":"Direct Kernel Perceptron (DKP): ultra-fast kernel ELM-based classification with non-iterative closed-form weight calculation","volume":"50","author":"M Fern\u00e1ndez-Delgado","year":"2014","journal-title":"Neural Netw"},{"issue":"06","key":"ref12","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1164\/rccm.201404-0716CP","article-title":"Gleaning knowledge from data in the intensive care unit","volume":"190","author":"M R Pinsky","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"issue":"06","key":"ref13","doi-asserted-by":"crossref","first-page":"e016403","DOI":"10.1136\/bmjopen-2017-016403","article-title":"Association between preoperative anaemia with length of hospital stay among patients undergoing primary total knee arthroplasty in Singapore: a single-centre retrospective study","volume":"7","author":"H R Abdullah","year":"2017","journal-title":"BMJ Open"},{"issue":"09","key":"ref14","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1542\/hpeds.2014-0246","article-title":"Risk factors for prolonged length of stay or complications during pediatric respiratory hospitalizations","volume":"5","author":"S V Kaiser","year":"2015","journal-title":"Hosp Pediatr"},{"issue":"04","key":"ref15","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1177\/1941874416641467","article-title":"Predictors of prolonged hospital stay in status migrainosus","volume":"6","author":"S Y Modi","year":"2016","journal-title":"Neurohospitalist"},{"issue":"11","key":"ref16","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1302\/0301-620X.90B11.20687","article-title":"Pre-operative predictors of the length of hospital stay in total knee replacement","volume":"90","author":"I D Smith","year":"2008","journal-title":"J Bone Joint Surg Br"},{"issue":"03","key":"ref17","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1054\/arth.2001.21495","article-title":"Sequential bilateral total knee arthroplasty under 1 anesthetic in patients > or = 75 years old: complications and functional outcomes","volume":"16","author":"A Adili","year":"2001","journal-title":"J Arthroplasty"},{"issue":"12","key":"ref18","doi-asserted-by":"crossref","first-page":"3729","DOI":"10.1016\/j.arth.2017.06.038","article-title":"Effect of type 2 diabetes on in-hospital postoperative complications and mortality after primary total hip and knee arthroplasty","volume":"32","author":"M A Mart\u00ednez-Huedo","year":"2017","journal-title":"J Arthroplasty"},{"issue":"01","key":"ref19","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00590-011-0915-6","article-title":"Trends 2001 to 2008 in incidence and immediate postoperative outcomes for major joint replacement among Spanish adults suffering diabetes","volume":"23","author":"M A Martinez-Huedo","year":"2013","journal-title":"Eur J Orthop Surg Traumatol"},{"issue":"11","key":"ref20","doi-asserted-by":"crossref","first-page":"3570","DOI":"10.1007\/s11999-014-3891-4","article-title":"Do patients with insulin-dependent and noninsulin-dependent diabetes have different risks for complications after arthroplasty?","volume":"472","author":"F Lovecchio","year":"2014","journal-title":"Clin Orthop Relat Res"},{"issue":"11","key":"ref21","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1002\/lt.22152","article-title":"Multivessel coronary artery disease predicts mortality, length of stay, and pressor requirements after liver transplantation","volume":"16","author":"C M Yong","year":"2010","journal-title":"Liver Transpl"},{"issue":"05","key":"ref22","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1007\/s11999-011-1804-3","article-title":"2010 Mid-America Orthopaedic Association Physician in Training Award: predictors of early adverse outcomes after knee and hip arthroplasty in geriatric patients","volume":"469","author":"C A Higuera","year":"2011","journal-title":"Clin Orthop Relat Res"},{"issue":"09","key":"ref23","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1016\/j.arth.2018.04.009","article-title":"Risk of ischemic stroke after perioperative atrial fibrillation in total knee and hip arthroplasty patients","volume":"33","author":"S Khormaee","year":"2018","journal-title":"J Arthroplasty"},{"issue":"06","key":"ref24","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1007\/s00167-014-3313-x","article-title":"Predictive factors of length of hospital stay after primary total knee arthroplasty","volume":"23","author":"L van den Belt","year":"2015","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"12","key":"ref25","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1016\/j.arth.2016.07.026","article-title":"Length of hospitalization after joint arthroplasty: does early discharge affect complications and readmission rates?","volume":"31","author":"J E Otero","year":"2016","journal-title":"J Arthroplasty"},{"issue":"10","key":"ref26","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1016\/j.arth.2014.05.007","article-title":"Focused risk analysis: regression model based on 5,314 total hip and knee arthroplasty patients from a single institution","volume":"29","author":"I A Inneh","year":"2014","journal-title":"J Arthroplasty"},{"issue":"03","key":"ref27","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/21548331.2016.1178579","article-title":"The association between smoking status and hospital length of stay: evidence from a hospital-based cohort","volume":"44","author":"S Rezaei","year":"2016","journal-title":"Hosp Pract (1995)"},{"issue":"07","key":"ref28","doi-asserted-by":"crossref","first-page":"e456","DOI":"10.1097\/CCM.0000000000001660","article-title":"Using supervised machine learning to classify real alerts and artifact in online multisignal vital sign monitoring data","volume":"44","author":"L Chen","year":"2016","journal-title":"Crit Care Med"}],"container-title":["The Journal of Knee Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1710573.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,25]],"date-time":"2021-12-25T00:01:27Z","timestamp":1640390487000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1710573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,8]]},"references-count":28,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2021,12,24]]},"published-print":{"date-parts":[[2022,1]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1710573","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1538-8506","1938-2480"],"issn-type":[{"value":"1538-8506","type":"print"},{"value":"1938-2480","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,8]]}}}