{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T15:12:36Z","timestamp":1777648356341,"version":"3.51.4"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"12","funder":[{"DOI":"10.13039\/100006545","name":"National Institute on Minority Health and Health Disparities","doi-asserted-by":"crossref","award":["R01 MD007796"],"award-info":[{"award-number":["R01 MD007796"]}],"id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>\n            Objective\u2003The aim of this study is to examine factors associated with early neonatal (death within first 7 days of birth) and infant (death during the first year of life) mortality among infants born with myelomeningocele.<\/jats:p><jats:p>\n            Study Design\u2003We examined linked data from the California Perinatal Quality Care Collaborative, vital records, and hospital discharge records for infants born with myelomeningocele from 2006 to 2011. Survival probability was calculated using Kaplan\u2013Meier Product Limit method and 95% confidence intervals (CI) using Greenwood's method; Cox proportional hazard models were used to estimate unadjusted and adjusted hazard ratios (HR) and 95% CI.<\/jats:p><jats:p>\n            Results\u2003Early neonatal and first-year survival probabilities among infants born with myelomeningocele were 96.0% (95% CI: 94.1\u201397.3%) and 94.5% (95% CI: 92.4\u201396.1%), respectively. Low birthweight and having multiple co-occurring birth defects were associated with increased HRs ranging between 5 and 20, while having congenital hydrocephalus and receiving hospital transfer from the birth hospital to another hospital for myelomeningocele surgery were associated with HRs indicating a protective association with early neonatal and infant mortality.<\/jats:p><jats:p>\n            Conclusion\u2003Maternal race\/ethnicity and social disadvantage did not predict early neonatal and infant mortality among infants with myelomeningocele; presence of congenital hydrocephalus and the role of hospital transfer for myelomeningocele repair should be further examined.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0040-1712165","type":"journal-article","created":{"date-parts":[[2020,5,30]],"date-time":"2020-05-30T22:31:52Z","timestamp":1590877912000},"page":"1263-1270","source":"Crossref","is-referenced-by-count":9,"title":["Factors Associated with Early Neonatal and First-Year Mortality in Infants with Myelomeningocele in California from 2006 to 2011"],"prefix":"10.1055","volume":"38","author":[{"given":"Vijaya","family":"Kancherla","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Emory University, Rollins School of Public Health, Atlanta, Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Ma","sequence":"additional","affiliation":[{"name":"Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Grant","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Stanford University School of Medicine, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry C.","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California"},{"name":"California Perinatal Quality Care Collaborative, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan R.","family":"Hintz","sequence":"additional","affiliation":[{"name":"Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California"},{"name":"California Perinatal Quality Care Collaborative, Stanford, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzan L.","family":"Carmichael","sequence":"additional","affiliation":[{"name":"Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California"},{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Stanford University, Stanford, 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