{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:26:29Z","timestamp":1790677589149,"version":"4.1.0"},"reference-count":59,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T00:00:00Z","timestamp":1595462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ortop (Sao Paulo)"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Resumo<\/jats:title><jats:p>A estenose degenerativa do canal vertebral lombar \u00e9 a causa mais frequente de dor lombar e\/ou ci\u00e1tica no paciente idoso; sua epidemiologia, fisiopatogenia, manifesta\u00e7\u00f5es e testes cl\u00ednicos s\u00e3o revistos em ampla investiga\u00e7\u00e3o bibliogr\u00e1fica atual. A import\u00e2ncia da rela\u00e7\u00e3o entre a cl\u00ednica e o estudo por imagens, principalmente a resson\u00e2ncia magn\u00e9tica (RM), \u00e9 ressaltada. Antes da indica\u00e7\u00e3o do tratamento, \u00e9 necess\u00e1rio identificar a localiza\u00e7\u00e3o precisa da dor, bem como o diagn\u00f3stico diferencial entre a claudica\u00e7\u00e3o neurog\u00eanica e a vascular. O tratamento conservador associando medica\u00e7\u00f5es com as diversas t\u00e9cnicas fisioter\u00e1picas resolve o problema na maioria dos casos, j\u00e1 o teste terap\u00eautico com os bloqueios, seja epidural, foraminal ou facet\u00e1rio, \u00e9 realizado quando as dores n\u00e3o cedem com o tratamento conservador e antes da indica\u00e7\u00e3o da cirurgia. Os bloqueios costumam dar melhores resultados no al\u00edvio dos sintomas de ciatalgia e menos no quadro de claudica\u00e7\u00e3o neurog\u00eanica. A descompress\u00e3o da cauda equina e\/ou radicular associada ou n\u00e3o \u00e0 artrodese \u00e9 o padr\u00e3o ouro quando a interven\u00e7\u00e3o cir\u00fargica \u00e9 necess\u00e1ria. A artrodese ap\u00f3s a descompress\u00e3o \u00e9 necess\u00e1ria nos casos com instabilidade segmentar, como na espondilolistese degenerativa. Quando a estenose de canal acontece em m\u00faltiplos n\u00edveis e vem acompanhada de desvio de eixo, seja coronal e\/ou sagital, deve ser realizada, al\u00e9m das descompress\u00f5es e artrodese, a corre\u00e7\u00e3o dos desvios de eixo, principalmente o eixo sagital, quando a corre\u00e7\u00e3o da lordose lombar se imp\u00f5e com t\u00e9cnicas que corrigem a lordose retificada para valores pr\u00f3ximos \u00e0 incid\u00eancia p\u00e9lvica.<\/jats:p>","DOI":"10.1055\/s-0040-1712490","type":"journal-article","created":{"date-parts":[[2020,7,23]],"date-time":"2020-07-23T22:52:59Z","timestamp":1595544779000},"page":"009-017","source":"Crossref","is-referenced-by-count":19,"title":["Estenose degenerativa do canal lombar"],"prefix":"10.1055","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3948-3057","authenticated-orcid":false,"given":"Sergio","family":"Hennemann","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Ortopedia, Grupo da coluna, Hospital M\u00e3e de Deus, Porto Alegre, RS, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0386-0295","authenticated-orcid":false,"given":"Marcelo Rodrigues","family":"de Abreu","sequence":"additional","affiliation":[{"name":"Radiologia Musculoesquel\u00e9tica, Hospital M\u00e3e de Deus, Porto Alegre, RS, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,7,23]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1302\/0301-620X.59B2.873978","article-title":"The morphometry and pathological anatomy of the lumbar spine in South African negroes and caucasoids with specific reference to spinal stenosis","volume":"59","author":"S Eisenstein","year":"1977","journal-title":"J Bone Joint Surg Br"},{"issue":"115","key":"ref2","first-page":"77","article-title":"Clinical features of lumbar spinal stenosis","author":"K W Paine","year":"1976","journal-title":"Clin Orthop Relat Res"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1097\/00007632-199318110-00012","article-title":"Decompression for degenerative spondylolisthesis and spinal stenosis at L4-5. The effects on facet joint morphology","volume":"18","author":"L J Grobler","year":"1993","journal-title":"Spine (Phila Pa 1976)"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00007632-199201000-00001","article-title":"Surgery for lumbar spinal stenosis. Attempted meta-analysis of the literature","volume":"17","author":"J A Turner","year":"1992","journal-title":"Spine (Phila Pa 1976)"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/jor.1100070116","article-title":"Dynamic changes in the dimensions of the lumbar spinal canal: an experimental study in vitro","volume":"7","author":"N Sch\u00f6nstr\u00f6m","year":"1989","journal-title":"J Orthop Res"},{"issue":"10","key":"ref6","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1097\/00007632-199505150-00013","article-title":"Lumbar spinal stenosis. Clinical and radiologic features","volume":"20","author":"T Amundsen","year":"1995","journal-title":"Spine (Phila Pa 1976)"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/00007632-197812000-00004","article-title":"Pathology and pathogenesis of lumbar spondylosis and stenosis","volume":"3","author":"W H Kirkaldy-Willis","year":"1978","journal-title":"Spine (Phila Pa 1976)"},{"issue":"14","key":"ref8","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1097\/BRS.0000000000002493","article-title":"Facet Sagittal Orientation: Possible Role in the Pathology of Degenerative Lumbar Spinal Stenosis","volume":"43","author":"X Liu","year":"2018","journal-title":"Spine (Phila Pa 1976)"},{"issue":"15","key":"ref9","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1097\/BRS.0000000000001476","article-title":"ISSLS Prize Winner: Consensus on the Clinical Diagnosis of Lumbar Spinal Stenosis: Results of an International Delphi Study","volume":"41","author":"C Tomkins-Lane","year":"2016","journal-title":"Spine (Phila Pa 1976)"},{"issue":"01","key":"ref10","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2106\/00004623-199072010-00018","article-title":"Experimental lumbar spinal stenosis. Analysis of the cortical evoked potentials, microvasculature, and histopathology","volume":"72","author":"R B Delamarter","year":"1990","journal-title":"J Bone Joint Surg Am"},{"issue":"01","key":"ref11","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/00007632-198401000-00004","article-title":"Pathoanatomy and pathophysiology of nerve root compression","volume":"9","author":"B Rydevik","year":"1984","journal-title":"Spine (Phila Pa 1976)"},{"issue":"07","key":"ref12","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1097\/BRS.0b013e3181bc9454","article-title":"Variation in eligibility criteria from studies of radiculopathy due to a herniated disc and of neurogenic claudication due to lumbar spinal stenosis: a structured literature review","volume":"35","author":"S Genevay","year":"2010","journal-title":"Spine (Phila Pa 1976)"},{"issue":"01","key":"ref13","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1148\/radiol.12111930","article-title":"Radiologic criteria for the diagnosis of spinal stenosis: results of a Delphi survey","volume":"264","author":"N Mamisch","year":"2012","journal-title":"Radiology"},{"issue":"03","key":"ref14","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jor.2015.06.001","article-title":"Lumbar spinal canal stenosis-special features","volume":"12","author":"P Gopinathan","year":"2015","journal-title":"J Orthop"},{"key":"ref15","first-page":"1451","volume-title":"The spine","author":"M Castillo","year":"1998"},{"key":"ref16","first-page":"e807","volume-title":"Neurogenic Intermittent Claudication with Special Reference to Stenosis of the Lumbar Vertebral Canal in Hand Book of Clinical Radiology","author":"H Verbiest","year":"1976"},{"issue":"02","key":"ref17","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/00007632-199302000-00020","article-title":"Lumbar spinal stenosis: clinical\/radiologic therapeutic evaluation in 145 patients. Conservative treatment or surgical intervention?","volume":"18","author":"D Onel","year":"1993","journal-title":"Spine (Phila Pa 1976)"},{"issue":"01","key":"ref18","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3233\/BMR-2010-0245","article-title":"Physical therapy treatment options for lumbar spinal stenosis","volume":"23","author":"C C Tomkins","year":"2010","journal-title":"J Back Musculoskeletal Rehabil"},{"issue":"03","key":"ref19","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/00007632-199003000-00010","article-title":"Centralization phenomenon. Its usefulness in evaluating and treating referred pain","volume":"15","author":"R Donelson","year":"1990","journal-title":"Spine (Phila Pa 1976)"},{"issue":"03","key":"ref20","first-page":"CD007076","article-title":"Pregabalin for acute and chronic pain in adults","author":"R A Moore","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"issue":"11","key":"ref21","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.2106\/00004623-200011000-00012","article-title":"The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study","volume":"82","author":"K D Riew","year":"2000","journal-title":"J Bone Joint Surg Am"},{"issue":"06","key":"ref22","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1097\/00007632-199106000-00003","article-title":"The effect of decompression on the natural course of spinal stenosis. A comparison of surgically treated and untreated patients","volume":"16","author":"K E Johnsson","year":"1991","journal-title":"Spine (Phila Pa 1976)"},{"issue":"14","key":"ref23","doi-asserted-by":"crossref","first-page":"E857","DOI":"10.1097\/BRS.0000000000001635","article-title":"Surgical Versus Nonsurgical Treatment for Lumbar Spinal Stenosis","volume":"41","author":"F Zaina","year":"2016","journal-title":"Spine (Phila Pa 1976)"},{"issue":"19","key":"ref24","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1097\/BRS.0b013e3182541955","article-title":"Predictors of treatment choice in lumbar spinal stenosis: a spine patient outcomes research trial study","volume":"37","author":"M F Kurd","year":"2012","journal-title":"Spine (Phila Pa 1976)"},{"issue":"08","key":"ref25","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1097\/01.brs.0000158953.57966.c0","article-title":"Long-term outcomes of surgical and nonsurgical management of lumbar spinal stenosis: 8 to 10 year results from the maine lumbar spine study","volume":"30","author":"S J Atlas","year":"2005","journal-title":"Spine (Phila Pa 1976)"},{"issue":"01","key":"ref26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.brs.0000251014.81875.6d","article-title":"Surgical or nonoperative treatment for lumbar spinal stenosis? A randomized controlled trial","volume":"32","author":"A Malmivaara","year":"2007","journal-title":"Spine (Phila Pa 1976)"},{"issue":"11","key":"ref27","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1097\/00007632-200006010-00016","article-title":"Lumbar spinal stenosis: conservative or surgical management?: A prospective 10-year study","volume":"25","author":"T Amundsen","year":"2000","journal-title":"Spine (Phila Pa 1976)"},{"issue":"06","key":"ref28","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.spinee.2019.01.003","article-title":"Effect of spinal decompression on back pain in lumbar spinal stenosis: a Canadian Spine Outcomes Research Network (CSORN) study","volume":"19","author":"S Srinivas","year":"2019","journal-title":"Spine J"},{"issue":"20","key":"ref29","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1097\/BRS.0b013e3182a056c1","article-title":"Lumbar spinous process splitting decompression provides equivalent outcomes to conventional midline decompression in degenerative lumbar canal stenosis: a prospective, randomized controlled study of 51 patients","volume":"38","author":"S Rajasekaran","year":"2013","journal-title":"Spine (Phila Pa 1976)"},{"issue":"03","key":"ref30","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3171\/spi.2007.6.3.229","article-title":"Split-spinous process laminotomy and discectomy for degenerative lumbar spinal stenosis: a preliminary report","volume":"6","author":"D Y Cho","year":"2007","journal-title":"J Neurosurg Spine"},{"issue":"24","key":"ref31","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1097\/BRS.0000000000002708","article-title":"Efficacy and Safety of Full-endoscopic Decompression via Interlaminar Approach for Central or Lateral Recess Spinal Stenosis of the Lumbar Spine: A Meta-analysis","volume":"43","author":"C H Lee","year":"2018","journal-title":"Spine (Phila Pa 1976)"},{"issue":"S 04","key":"ref32","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s00586-018-5656-3","article-title":"Full endoscopic, bilateral over-the-top decompression for lumbar spinal stenosis","volume":"27","author":"C J Siepe","year":"2018","journal-title":"Eur Spine J"},{"issue":"03","key":"ref33","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1227\/01.NEU.0000255332.87909.58","article-title":"Minimally invasive lumbar spinal decompression in the elderly: outcomes of 50 patients aged 75 years and older","volume":"60","author":"D S Rosen","year":"2007","journal-title":"Neurosurgery"},{"key":"ref34","first-page":"42","article-title":"Percutaneous Transforaminal Endoscopic Decompression for Lumbar Foraminal Stenosis","volume":"3","author":"Y H Woo","journal-title":"J Clin Exp Orthop"},{"issue":"01","key":"ref35","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1148\/radiol.2451051359","article-title":"Lumbar intervertebral instability: a review","volume":"245","author":"A Leone","year":"2007","journal-title":"Radiology"},{"issue":"02","key":"ref36","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1590\/S1808-18512011000200010","article-title":"Correla\u00e7\u00e3o entre instabilidade radiogr\u00e1fica e presen\u00e7a do sinal de modic","volume":"10","author":"L M da Costa","year":"2011","journal-title":"Coluna\/Columna"},{"issue":"384","key":"ref37","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/00003086-200103000-00004","article-title":"Decompression, fusion, and instrumentation surgery for complex lumbar spinal stenosis","volume":"200","author":"K K Hansraj","year":"2001","journal-title":"Clin Orthop Relat Res"},{"issue":"21","key":"ref38","doi-asserted-by":"crossref","first-page":"E1161","DOI":"10.1097\/BRS.0000000000001116","article-title":"Rationale for the Surgical Treatment of Lumbar Degenerative Spondylolisthesis","volume":"40","author":"G D Schroeder","year":"2015","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"2256S","DOI":"10.1097\/00007632-199410151-00002","article-title":"Degenerative lumbar spondylolisthesis. A meta-analysis of literature 1970-1993","volume":"19","author":"S M Mardjetko","year":"1994","journal-title":"Spine (Phila Pa 1976)"},{"issue":"23","key":"ref40","doi-asserted-by":"crossref","first-page":"E1408","DOI":"10.1097\/BRS.0000000000001638","article-title":"Posterolateral Fusion Versus Interbody Fusion for Degenerative Spondylolisthesis: A Systematic Review and Meta-Analysis","volume":"41","author":"S J McAnany","year":"2016","journal-title":"Spine (Phila Pa 1976)"},{"issue":"01","key":"ref41","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1186\/s13018-019-1266-y","article-title":"Open versus minimally invasive TLIF: literature review and meta-analysis","volume":"14","author":"A Hammad","year":"2019","journal-title":"J Orthop Surg Res"},{"issue":"18","key":"ref42","doi-asserted-by":"crossref","first-page":"E1124","DOI":"10.1097\/BRS.0000000000001510","article-title":"Modified Mini-open Transforaminal Lumbar Interbody Fusion: Description of Surgical Technique and Assessment of Free-hand Pedicle Screw Insertion","volume":"41","author":"P Pakzaban","year":"2016","journal-title":"Spine (Phila Pa 1976)"},{"issue":"09","key":"ref43","doi-asserted-by":"crossref","first-page":"E555","DOI":"10.1097\/BRS.0000000000002903","article-title":"Comparative Analysis of Two Transforaminal Lumbar Interbody Fusion Techniques: Open TLIF Versus Wiltse MIS TLIF","volume":"44","author":"D H Ge","year":"2019","journal-title":"Spine (Phila Pa 1976)"},{"issue":"12","key":"ref44","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1097\/01.brs.0000166618.42749.d1","article-title":"A multicenter, prospective, randomized trial evaluating the X STOP interspinous process decompression system for the treatment of neurogenic intermittent claudication: two-year follow-up results","volume":"30","author":"J F Zucherman","year":"2005","journal-title":"Spine (Phila Pa 1976)"},{"issue":"06","key":"ref45","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00586-009-0967-z","article-title":"Two-year results of interspinous spacer (X-Stop) implantation in 175 patients with neurologic intermittent claudication due to lumbar spinal stenosis","volume":"18","author":"J Kuchta","year":"2009","journal-title":"Eur Spine J"},{"issue":"02","key":"ref46","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s00586-009-1229-9","article-title":"Does an interspinous device (Coflex) improve the outcome of decompressive surgery in lumbar spinal stenosis? One-year follow up of a prospective case control study of 60 patients","volume":"19","author":"A Richter","year":"2010","journal-title":"Eur Spine J"},{"issue":"17","key":"ref47","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1097\/BRS.0b013e31828ba413","article-title":"X-stop versus decompressive surgery for lumbar neurogenic intermittent claudication: randomized controlled trial with 2-year follow-up","volume":"38","author":"B H Str\u00f6mqvist","year":"2013","journal-title":"Spine (Phila Pa 1976)"},{"issue":"07","key":"ref48","doi-asserted-by":"crossref","first-page":"e0199623","DOI":"10.1371\/journal.pone.0199623","article-title":"Interspinous process devices for treatment of degenerative lumbar spine stenosis: A systematic review and meta-analysis","volume":"13","author":"A W Poetscher","year":"2018","journal-title":"PLoS One"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"975052","DOI":"10.1155\/2014\/975052","article-title":"Controversies about interspinous process devices in the treatment of degenerative lumbar spine diseases: past, present, and future","volume":"2014","author":"R Gazzeri","year":"2014","journal-title":"BioMed Res Int"},{"issue":"04","key":"ref50","doi-asserted-by":"crossref","first-page":"E14","DOI":"10.3171\/2015.7.FOCUS15244","article-title":"Failure rates and complications of interspinous process decompression devices: a European multicenter study","volume":"39","author":"R Gazzeri","year":"2015","journal-title":"Neurosurg Focus"},{"issue":"03","key":"ref51","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0030-5898(20)31329-8","article-title":"The pathophysiology of degenerative disease of the lumbar spine","volume":"14","author":"K Yong-Hing","year":"1983","journal-title":"Orthop Clin North Am"},{"issue":"03","key":"ref52","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/01.brs.0000152379.54463.65","article-title":"Classification of the normal variation in the sagittal alignment of the human lumbar spine and pelvis in the standing position","volume":"30","author":"P Roussouly","year":"2005","journal-title":"Spine (Phila Pa 1976)"},{"issue":"06","key":"ref53","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1097\/01.brs.0000155425.04536.f7","article-title":"Correlation of radiographic parameters and clinical symptoms in adult scoliosis","volume":"30","author":"S D Glassman","year":"2005","journal-title":"Spine (Phila Pa 1976)"},{"issue":"20","key":"ref54","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1097\/01.brs.0000238970.67552.f5","article-title":"An analysis of sagittal spinal alignment following long adult lumbar instrumentation and fusion to L5 or S1: can we predict ideal lumbar lordosis?","volume":"31","author":"Y J Kim","year":"2006","journal-title":"Spine (Phila Pa 1976)"},{"issue":"08","key":"ref55","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1097\/BRS.0b013e31819d0c86","article-title":"Role of pelvic incidence, thoracic kyphosis, and patient factors on sagittal plane correction following pedicle subtraction osteotomy","volume":"34","author":"P S Rose","year":"2009","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"S312","DOI":"10.1097\/BRS.0b013e318202495f","article-title":"Adult deformity correction through minimally invasive lateral approach techniques","volume":"35","author":"G M Mundis","year":"2010","journal-title":"Spine (Phila Pa 1976)"},{"issue":"21","key":"ref57","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1097\/BRS.0b013e3182a43f0b","article-title":"Adult degenerative scoliosis treated with XLIF: clinical and radiographical results of a prospective multicenter study with 24-month follow-up","volume":"38","author":"F M Phillips","year":"2013","journal-title":"Spine (Phila Pa 1976)"},{"issue":"03","key":"ref58","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1590\/S1808-18512011000300015","article-title":"Op\u00e7\u00e3o minimamente invasiva lateral para artrodese intersom\u00e1tica t\u00f3raco-lombar","volume":"10","author":"R Amaral","year":"2011","journal-title":"Coluna\/Columna"},{"issue":"06","key":"ref59","first-page":"e1389","article-title":"Minimally invasive scoliosis surgery with oblique lateral lumbar interbody fusion: single surgeon feasibility","volume":"9","author":"H Abbasi","year":"2017","journal-title":"Cureus"}],"container-title":["Revista Brasileira de Ortopedia"],"original-title":[],"language":"pt","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1712490.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T00:17:54Z","timestamp":1613780274000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1712490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,23]]},"references-count":59,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2021,2,19]]},"published-print":{"date-parts":[[2021,2]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1712490","relation":{},"ISSN":["0102-3616","1982-4378"],"issn-type":[{"value":"0102-3616","type":"print"},{"value":"1982-4378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,23]]}}}