{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:36:23Z","timestamp":1762868183395,"version":"3.37.3"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"12","funder":[{"name":"Jeanne et Jean-Louis L\u00e9vesque Perinatal Research Chair\u2014Universit\u00e9 Laval"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>\n            Objective\u2003This study was aimed to estimate the value of transabdominal (TA) ultrasound measurement of cervical length (CL), as an alternative of transvaginal (TV) ultrasound, for universal screening of short cervix in the midtrimester.<\/jats:p><jats:p>\n            Study Design\u2003We conducted a prospective cohort study of nulliparous women with singleton pregnancy at 20 to 24 weeks of gestation. All participants underwent TA ultrasound followed by TV ultrasound with acquisitions of images and videos of the uterine cervix. A second sonographer, blinded to the participants' data and pregnancy outcomes, measured the CL using TA and TV images and videos. Pearson's correlation test and receiver operating characteristic (ROC) curve analyses were performed.<\/jats:p><jats:p>\n            Results\u2003A total of 805 participants were recruited, including 780 (97%) where TA CL measurement was feasible. We observed a strong correlation of CL between TA and TV (correlation coefficient: 0.57; p\u2009&lt;\u20090.0001) with a mean TA measurement being 4\u2009mm (95% confidence interval [CI]: \u22126 to 14\u2009mm) below the mean TV measurement (mean of differences: 5\u2009\u00b1\u20094\u2009mm). We observed that a TA CL &lt;30\u2009mm was highly predictive of a short cervix defined as a TV CL \u226425\u2009mm (area under the ROC curve: 0.97; 95% CI: 0.95\u20130.99; p\u2009&lt;\u20090.0001) with a sensitivity of 100% and a false-positive rate of 22%.<\/jats:p><jats:p>\n            Conclusion\u2003Universal short cervix screening in nulliparous women could be performed using TA ultrasound, which could allow the avoidance of TV ultrasound in more than three quarter of women. In low-risk population, TV ultrasound could be reserved to women with TA CL &lt;30\u2009mm.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0040-1712950","type":"journal-article","created":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T23:22:11Z","timestamp":1591831331000},"page":"1303-1307","source":"Crossref","is-referenced-by-count":2,"title":["Ultrasonographic Transabdominal Measurement of Uterine Cervical Length for the Prediction of a Midtrimester Short Cervix"],"prefix":"10.1055","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2662-4351","authenticated-orcid":false,"given":"Paul","family":"Guerby","sequence":"additional","affiliation":[{"name":"Reproduction, Mother and Child Health Unit, Research Center of the CHU de Qu\u00e9bec\u2013Universit\u00e9 Laval, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie","family":"Beaudoin","sequence":"additional","affiliation":[{"name":"Reproduction, Mother and Child Health Unit, Research Center of the CHU de Qu\u00e9bec\u2013Universit\u00e9 Laval, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevi\u00e8ve","family":"Marcoux","sequence":"additional","affiliation":[{"name":"Reproduction, Mother and Child Health Unit, Research Center of the CHU de Qu\u00e9bec\u2013Universit\u00e9 Laval, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Girard","sequence":"additional","affiliation":[{"name":"Reproduction, Mother and Child Health Unit, Research Center of the CHU de Qu\u00e9bec\u2013Universit\u00e9 Laval, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Charles","family":"Pasquier","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Universit\u00e9 de Sherbrooke, Facult\u00e9 de m\u00e9decine et des sciences de la sant\u00e9 3001, Sherbrooke, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6936-4369","authenticated-orcid":false,"given":"Emmanuel","family":"Bujold","sequence":"additional","affiliation":[{"name":"Reproduction, Mother and Child Health Unit, Research Center of the CHU de Qu\u00e9bec\u2013Universit\u00e9 Laval, Quebec, Canada"},{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Faculty of Medicine, Universit\u00e9 Laval, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,6,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1126\/science.1251816","article-title":"Preterm labor: one syndrome, many causes","volume":"345","author":"R Romero","year":"2014","journal-title":"Science"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1016\/S0140-6736(12)60820-4","article-title":"National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications","volume":"379","author":"H Blencowe","year":"2012","journal-title":"Lancet"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/uog.17556","article-title":"Transvaginal sonographic cervical length in first and second trimesters in a low-risk population: a prospective study","volume":"51","author":"C B Wulff","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ajog.2018.03.028","article-title":"Vaginal progesterone is as effective as cervical cerclage to prevent preterm birth in women with a singleton gestation, previous spontaneous preterm birth, and a short cervix: updated indirect comparison meta-analysis","volume":"219","author":"A Conde-Agudelo","year":"2018","journal-title":"Am J Obstet Gynecol"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/uog.17357","article-title":"Interventions for women with mid-trimester short cervix: which ones work?","volume":"49","author":"A M Vintzileos","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.jogc.2018.09.019","article-title":"No. 374-universal cervical length screening","volume":"41","author":"K Butt","year":"2019","journal-title":"J Obstet Gynaecol Can"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1097\/AOG.0b013e3182723b1b","article-title":"Gynecologists. 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