{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:24:21Z","timestamp":1761578661015,"version":"3.37.3"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003A certain degree of prosthesis oversizing is recommended for the SAPIEN 3 (S3; Edwards Lifesciences Corp., Irvine, California, United States) to ensure device success. We aimed to investigate midterm outcomes in patients who received oversized (OS) S3 valve after transapical\u2013transcatheter aortic valve replacement (TA-TAVR).<\/jats:p><jats:p>\n          Methods\u2003Out of 122 patients with aortic stenosis who underwent TA-TAVR using S3 at our institution, 42 received OS prosthesis. We used computed tomography (CT) derived effective diameter to assess oversizing. We defined oversizing if the labeled diameter of the selected valve for implantation was \u22652\u2009mm bigger than the effective annulus diameter calculated by the annulus area. We conducted a midterm follow-up and compared the OS cohort with the non-OS (nOS) cohort.<\/jats:p><jats:p>\n          Results\u2003The study groups showed similar risk score and age (STS [Society of Thoracic Surgery] score: 5.4\u2009\u00b1\u20093; mean age: 80.7\u2009\u00b1\u20095.7). The 30-day mortality was 7.1% in OS versus 2.4% in nOS. The 30-day all-stroke was 2.4% in OS versus 0% in nOS. The 1- and 3-year all-cause mortality were 28.5 and 42.8% in OS versus 21.9 and 26.8% in nOS, respectively. Midterm freedom from death and from cardiocerebral events was similar in both groups. Moderate\/severe paravalvular leakage occurred in 0% in OS versus 5.4% in nOS. The postdilation rate was 7.1% in OS versus 15.3% in nOS. The rate of new permanent pacemaker implantation (PPI) was 15.7% in OS versus 9.3% in nOS. The STS score was detected as an independent predictor of mortality.<\/jats:p><jats:p>\n          Conclusion\u2003Oversizing reduces the risk of device failure and intraprocedural postdilation but increases the risk of PPI. Early and midterm morbidity and mortality after OS and nOS with S3 are comparable.<\/jats:p>","DOI":"10.1055\/s-0040-1713168","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T23:12:38Z","timestamp":1595286758000},"page":"445-454","source":"Crossref","is-referenced-by-count":2,"title":["Oversized versus Non-oversized Prosthesis: Midterm Outcomes after Transcatheter Aortic Valve Replacement Using SAPIEN 3 Valve"],"prefix":"10.1055","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8312-330X","authenticated-orcid":false,"given":"Dritan","family":"Useini","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Ruhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blerta","family":"Beluli","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, St. Anna Hospital, Herne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hildegard","family":"Christ","sequence":"additional","affiliation":[{"name":"Institute of Medical Statistics and Computational Biology (IMSB), University Hospital of Cologne, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"M\u00fcgge","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Ruhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polykarpos","family":"Patsalis","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Ruhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Schl\u00f6micher","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Ruhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Haldenwang","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Ruhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Bechtel","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Ruhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justus","family":"Strauch","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Ruhr-University Hospital Bergmannsheil, Bochum, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,7,20]]},"reference":[{"issue":"14","key":"ref1","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.jacc.2011.12.015","article-title":"3-dimensional aortic annular assessment by multidetector computed tomography predicts moderate or severe paravalvular regurgitation after transcatheter aortic valve replacement: a multicenter retrospective analysis","volume":"59","author":"A B Willson","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jcin.2012.09.019","article-title":"Transcatheter aortic valve replacement with the SAPIEN 3: a new balloon-expandable transcatheter heart valve","volume":"6","author":"R K Binder","year":"2013","journal-title":"JACC Cardiovasc Interv"},{"issue":"03","key":"ref3","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.jcin.2015.09.036","article-title":"Predictors of permanent pacemaker implantations and new-onset conduction abnormalities with the SAPIEN 3 Balloon-Expandable Transcatheter Heart Valve","volume":"9","author":"O Husser","year":"2016","journal-title":"JACC Cardiovasc Interv"},{"issue":"08","key":"ref4","first-page":"641","article-title":"Multicenter evaluation of prosthesis oversizing of the SAPIEN 3 Transcatheter Heart Valve. Impact on device failure and new pacemaker implantations","volume":"72","author":"C Pellegrini","year":"2019","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jtcvs.2012.09.002","article-title":"Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document","volume":"145","author":"A P Kappetein","year":"2013","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"06","key":"ref6","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jcct.2012.11.002","article-title":"SCCT expert consensus document on computed tomography imaging before transcatheter aortic valve implantation (TAVI)\/transcatheter aortic valve replacement (TAVR)","volume":"6","author":"S Achenbach","year":"2012","journal-title":"J Cardiovasc Comput 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heart valve replacement with the SAPIEN 3: a comparison with the SAPIEN XT","volume":"8","author":"T H Yang","year":"2015","journal-title":"JACC Cardiovasc Interv"},{"issue":"10","key":"ref10","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1001\/jama.2016.12347","article-title":"Association between transcatheter aortic valve replacement and subsequent infective endocarditis and in-hospital Death","volume":"316","author":"A Regueiro","year":"2016","journal-title":"JAMA"},{"issue":"07","key":"ref11","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1093\/eurheartj\/ehu384","article-title":"Paravalvular regurgitation after transcatheter aortic valve replacement with the Edwards SAPIEN valve in the PARTNER trial: characterizing patients and impact on outcomes","volume":"36","author":"S Kodali","year":"2015","journal-title":"Eur Heart J"},{"issue":"05","key":"ref12","doi-asserted-by":"crossref","first-page":"444","DOI":"10.21037\/acs.2017.09.15","article-title":"Pros and 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transcatheter aortic valve replacement with the SAPIEN 3 valve","volume":"2","author":"P Pibarot","year":"2017","journal-title":"JAMA Cardiol"},{"issue":"15","key":"ref19","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1016\/j.jacc.2013.01.047","article-title":"Incidence, predictors, and outcomes of aortic regurgitation after transcatheter aortic valve replacement: meta-analysis and systematic review of literature","volume":"61","author":"G Athappan","year":"2013","journal-title":"J Am Coll Cardiol"},{"issue":"21","key":"ref20","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1016\/j.jacc.2014.09.026","article-title":"Multicenter evaluation of a next-generation balloon-expandable transcatheter aortic valve","volume":"64","author":"J Webb","year":"2014","journal-title":"J Am Coll Cardiol"},{"issue":"01","key":"ref21","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/joic.12182","article-title":"First experience with the new generation Edwards SAPIEN 3 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