{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T07:08:58Z","timestamp":1774076938737,"version":"3.50.1"},"reference-count":6,"publisher":"Scientific Scholar","license":[{"start":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T00:00:00Z","timestamp":1591920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ruralneuropractice.com"],"crossmark-restriction":true},"short-container-title":["JNRP"],"abstract":"<jats:title>Abstract<\/jats:title>\n<jats:p>Wernicke\u2019s encephalopathy is an acute neurological disorder caused due to thiamine deficiency. It is characterized by a triad of confusion, ataxia, and ophthalmoplegia. Wernicke\u2019s encephalopathy can present with atypical clinical manifestations, particularly in setting of nonalcoholic background. Our patient manifested with clinical complaints of acute drowsiness, speech difficulty, and ataxia. Magnetic resonance imaging of the brain revealed T2 hyperintensity in bilateral medial thalami, globus pallidus, periaqueductal gray matter, dorsal pons, and dorsal medulla. The diagnosis of Wernicke\u2019s encephalopathy was entertained and he well responded to parental thiamine therapy. The clinician should be aware about atypical presentation of Wernicke\u2019s encephalopathy.<\/jats:p>","DOI":"10.1055\/s-0040-1713334","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T22:41:02Z","timestamp":1592001662000},"page":"487-488","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Wernicke\u2019s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation"],"prefix":"10.25259","volume":"11","author":[{"given":"Rajesh","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Neurology, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chetan","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Neurology, King George\u2019s Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2020,6,12]]},"reference":[{"key":"10.1055\/s-0040-1713334\/ref-1","first-page":"229","article-title":"Die akuteh\u00e4morrhagischepolioencephalitis superior","volume-title":"Lehrbuch der Gehirnkrankheitenf\u00fcr\u00c4rzte und Studierende","volume":"Vol. II","author":"Wernicke","year":"1881"},{"issue":"4","key":"10.1055\/s-0040-1713334\/ref-2","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1136\/jnnp.49.4.341","article-title":"Clinical signs in the Wernicke-Korsakoff complex: a retrospective analysis of 131 cases diagnosed at necropsy","volume":"49","author":"Harper","year":"1986","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"7","key":"10.1055\/s-0040-1713334\/ref-3","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1136\/jnnp.46.7.593","article-title":"The incidence of Wernicke\u2019s encephalopathy in Australia\u2013a neuropathological study of 131 cases","volume":"46","author":"Harper","year":"1983","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"6","key":"10.1055\/s-0040-1713334\/ref-4","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1093\/alcalc\/37.6.513","article-title":"The Royal College of Physicians report on alcohol: guidelines for managing Wernicke\u2019s encephalopathy in the accident and Emergency Department","volume":"37","author":"Thomson","year":"2002","journal-title":"Alcohol Alcohol"},{"issue":"7","key":"10.1055\/s-0040-1713334\/ref-5","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.3174\/ajnr.A0544","article-title":"Wernicke encephalopathy: MR findings at clinical presentation in twenty-six alcoholic and nonalcoholic patients","volume":"28","author":"Zuccoli","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"issue":"10","key":"10.1055\/s-0040-1713334\/ref-6","doi-asserted-by":"crossref","first-page":"831","DOI":"10.2169\/internalmedicine.35.831","article-title":"Acute Wernicke\u2019s encephalopathy: comparison of magnetic resonance images and autopsy findings","volume":"35","author":"Suzuki","year":"1996","journal-title":"Intern Med"}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ruralneuropractice.com\/wernickes-encephalopathy-typical-disease-with-an-atypical-clinicoradiological-manifestation\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ruralneuropractice.com\/wernickes-encephalopathy-typical-disease-with-an-atypical-clinicoradiological-manifestation\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T04:41:10Z","timestamp":1691210470000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/wernickes-encephalopathy-typical-disease-with-an-atypical-clinicoradiological-manifestation\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,12]]},"references-count":6,"alternative-id":["10.1055\/s-0040-1713334"],"URL":"https:\/\/doi.org\/10.1055\/s-0040-1713334","relation":{},"ISSN":["0976-3147"],"issn-type":[{"value":"0976-3147","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,12]]},"article-number":"487"}}