{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:45:44Z","timestamp":1765295144033},"reference-count":9,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:p>As new information about coronavirus disease 2019 (COVID-19) is rapidly discovered, clinicians are better equipped to make informed decisions for their patients. While current research suggests COVID-19 viral antigen is not found in vaginal secretions, its detectability in the female lower genital tract may have clinical implications for obstetric and gynecologic care for women. We present a case of a woman at 31 weeks' gestation with simultaneous upper respiratory symptoms and vulvovaginitis. She was found to have a vulvar lesion positive for severe acute respiratory syndrome-COVID by viral swab. This case shows that COVID-19 is detectable in the vulva. This may have implications for health care workers' exposure and personal protective equipment needs. While vertical transmission has largely not been reported, the presence of detectable virus in the female lower genital tract makes this a continued possibility and area of study.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0040-1713665","type":"journal-article","created":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T22:39:56Z","timestamp":1593729596000},"page":"1183-1184","source":"Crossref","is-referenced-by-count":9,"title":["Detection of COVID-19 in a Vulvar Lesion"],"prefix":"10.1055","volume":"37","author":[{"given":"Stephanie A.","family":"Sansone","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth S.","family":"Rubin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adi","family":"Hirshberg","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth G.","family":"Clement","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sindhu K.","family":"Srinivas","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,7,2]]},"reference":[{"key":"ref1","first-page":"ciaa375","article-title":"SARS-CoV-2 is not detectable in the vaginal fluid of women with severe COVID-19 infection","author":"L Qiu","year":"2020","journal-title":"Clin Infect Dis"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.04.038","article-title":"Severe acute respiratory syndrome coronavirus 2 detection in the female lower genital tract","author":"P Cui","year":"2020","journal-title":"Am J Obstet Gynecol"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/ijd.14937","article-title":"Chilblain-like lesions on feet and hands during the COVID-19 Pandemic","volume":"59","author":"N Landa","year":"2020","journal-title":"Int J Dermatol"},{"issue":"10","key":"ref4","doi-asserted-by":"crossref","first-page":"2000180","DOI":"10.2807\/1560-7917.ES.2020.25.10.2000180","article-title":"Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020","volume":"25","author":"K Mizumoto","year":"2020","journal-title":"Euro Surveill"},{"issue":"22","key":"ref5","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1056\/NEJMc2009316","article-title":"Universal screening for SARS-CoV-2 in women admitted for delivery","volume":"382","author":"D Sutton","year":"2020","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"m1375","DOI":"10.1136\/bmj.m1375","article-title":"Covid-19: four fifths of cases are asymptomatic, China figures indicate","volume":"369","author":"M Day","year":"2020","journal-title":"BMJ"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2020-0901-SA","article-title":"An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes","author":"D A Schwartz","year":"2020","journal-title":"Arch Pathol Lab Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1710050","article-title":"Severe COVID-19 during pregnancy and possible vertical transmission","author":"M C Alzamora","year":"2020","journal-title":"Am J Perinatol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.4868","article-title":"Can SARS-CoV-2 infection be acquired in utero?: more definitive evidence is needed","author":"D W Kimberlin","year":"2020","journal-title":"JAMA"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1713665.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T22:37:15Z","timestamp":1598999835000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1713665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,2]]},"references-count":9,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020,9,1]]},"published-print":{"date-parts":[[2020,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1713665","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,2]]}}}