{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:40:47Z","timestamp":1780731647503,"version":"3.54.1"},"reference-count":36,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"10","license":[{"start":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T00:00:00Z","timestamp":1604102400000},"content-version":"vor","delay-in-days":30,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003The present study aims to determine if the use of cervical pessary plus progesterone in short-cervix (\u2264\u200925\u2009mm) dichorionic-diamniotic (DC-DA) twin pregnancies is equivalent to the rate of preterm births (PBs) with no intervention in unselected DC-DA twin pregnancies.<\/jats:p><jats:p>\n          Methods\u2003A historical cohort study was performed between 2010 and 2018, including a total of 57 pregnant women with DC-DA twin pregnancies. The women admitted from 2010 to 2012 (n\u2009=\u200932) received no treatment, and were not selected by cervical length (Non-Treated group, NTG), whereas those admitted from 2013 to 2018 (n\u2009=\u200925), were routinely submitted to cervical pessary plus progesterone after the diagnosis of short cervix from the 18th to the 27th weeks of gestation (Pessary-Progesterone group, PPG). The primary outcome analyzed was the rate of PBs before 34 weeks.<\/jats:p><jats:p>\n          Results\u2003There were no statistical differences between the NTG and the PPG regarding PB\u2009&lt;\u200934 weeks (18.8% versus 40.0% respectively; p\u2009=\u20090.07) and the mean birthweight of the smallest twin (2,037\u2009\u00b1\u2009425\u2009g versus 2,195\u2009\u00b1\u2009665\u2009g; p\u2009=\u20090.327). The Kaplan-Meyer Survival analysis was performed, and there were no differences between the groups before 31.5 weeks. Logistic regression showed that a previous PB (&lt; 37 weeks) presented an odds ratio (OR) of 15.951 (95% confidence interval [95%CI]: 1.294\u2013196.557; p\u2009=\u20090.031*) for PB\u2009&lt;\u200934 weeks in the PPG.<\/jats:p><jats:p>\n          Conclusion\u2003In DC-DA twin pregnancies with a short cervix, (which means a higher risk of PB), the treatment with cervical pessary plus progesterone could be considered equivalent in several aspects related to PB in the NTG, despite the big difference between these groups.<\/jats:p>","DOI":"10.1055\/s-0040-1713806","type":"journal-article","created":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T23:31:15Z","timestamp":1604187075000},"page":"621-629","source":"Crossref","is-referenced-by-count":7,"title":["Cervical Pessary Plus Progesterone for Twin Pregnancy with Short Cervix Compared to Unselected and Non-Treated Twin Pregnancy: A Historical Equivalence Cohort Study (EPM Twin Pessary Study)"],"prefix":"10.61622","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5145-1061","authenticated-orcid":false,"given":"Marcelo Santucci","family":"Fran\u00e7a","sequence":"additional","affiliation":[{"name":"Obstetrics Department, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7306-533X","authenticated-orcid":false,"given":"Alan Roberto","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"Obstetrics Department, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5010-7725","authenticated-orcid":false,"given":"Valter Lacerda de","family":"Andrade Junior","sequence":"additional","affiliation":[{"name":"Postgraduate Department, Faculdade Impacta, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1514-5504","authenticated-orcid":false,"given":"Julio","family":"Elito Junior","sequence":"additional","affiliation":[{"name":"Obstetrics Department, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0800-0761","authenticated-orcid":false,"given":"David Baptista Silva","family":"Pares","sequence":"additional","affiliation":[{"name":"Obstetrics Department, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2958-1921","authenticated-orcid":false,"given":"Tatiana Emy Nishimoto Kawanami","family":"Hamamoto","sequence":"additional","affiliation":[{"name":"Obstetrics Department, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4456-1905","authenticated-orcid":false,"given":"Stephanno Gomes Pereira","family":"Sarmento","sequence":"additional","affiliation":[{"name":"Obstetrics Department, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"},{"name":"Obstetrics and Gynecology Department, Faculdade de Medicina de Jundia\u00ed, Jundia\u00ed, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1405-5371","authenticated-orcid":false,"given":"Rosiane","family":"Mattar","sequence":"additional","affiliation":[{"name":"Obstetrics Department, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7963-1758","authenticated-orcid":false,"given":"Antonio Fernandes","family":"Moron","sequence":"additional","affiliation":[{"name":"Obstetrics Department, Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2020,10,31]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"publisher","first-page":"548.e1","DOI":"10.1016\/j.ajog.2009.12.005","article-title":"Universal cervical length screening and treatment with vaginal progesterone to prevent preterm birth: a decision and economic analysis","volume":"202","author":"A G Cahill","year":"2010","journal-title":"Am J Obstet Gynecol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1126\/science.1251816","article-title":"Preterm labor: one syndrome, many 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