{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:04:18Z","timestamp":1790888658918,"version":"4.1.0"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This article reviews the most common locations and natural history of sinonasal carcinomas. It also reviews surgical indications and current evidence regarding adjuvant and neoadjuvant therapies. In the past, orbital clearance was generally done for ethmoid and maxillary cancers, even without a marked neoplastic infiltration; however, such indications have changed in the recent years due to advances in our understanding of the disease, as well as new chemotherapeutic and radiotherapy protocols. Surgical resection of tumors close to the orbit exhibits the challenging task of balancing treatment goals and patient's desires.<\/jats:p>","DOI":"10.1055\/s-0040-1713937","type":"journal-article","created":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T00:10:52Z","timestamp":1597968652000},"page":"369-375","source":"Crossref","is-referenced-by-count":11,"title":["Sinonasal Malignancy and Orbital Exenteration Sparing Cancer Surgery"],"prefix":"10.1055","volume":"81","author":[{"given":"Camilo","family":"Reyes","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Endoscopic Skull Base Surgery, Department of Otolaryngology - Head and Neck Surgery, Augusta University, Augusta, Georgia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihir","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology - Head and Neck Surgery, Winship Cancer Institute at Emory University, Emory University, Atlanta, Geogia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Arturo","family":"Solares","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology - Head and Neck Surgery, Winship Cancer Institute at Emory University, Emory University, Atlanta, Geogia, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,8,20]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.nec.2012.08.004","article-title":"Sinonasal carcinomas: epidemiology, pathology, and management","volume":"24","author":"S K Haerle","year":"2013","journal-title":"Neurosurg Clin N Am"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1055\/s-0034-1390403","article-title":"To preserve or not to preserve the orbit in paranasal sinus neoplasms: a meta-analysis","volume":"76","author":"C Reyes","year":"2015","journal-title":"J Neurol Surg B Skull Base"},{"issue":"03","key":"ref3","first-page":"211","article-title":"[Magnetic resonance and computed tomography compared in the staging of rhinosinusal neoplasms. A cost-effectiveness evaluation]","volume":"91","author":"R Maroldi","year":"1996","journal-title":"Radiol Med (Torino)"},{"issue":"05","key":"ref4","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1002\/1097-0347(200008)22:5<456::AID-HED3>3.0.CO;2-N","article-title":"Preoperative imaging to predict orbital invasion by tumor","volume":"22","author":"M D Eisen","year":"2000","journal-title":"Head Neck"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2500\/ajr.2006.20.2889","article-title":"Periorbita: computed tomography and magnetic resonance imaging findings","volume":"20","author":"H J Kim","year":"2006","journal-title":"Am J Rhinol"},{"issue":"07","key":"ref6","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s11864-017-0484-y","article-title":"Overview of the 8th edition TNM Classification for Head and Neck Cancer","volume":"18","author":"S H Huang","year":"2017","journal-title":"Curr Treat Options Oncol"},{"issue":"02","key":"ref7","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/hed.10358","article-title":"Prognostic factors in sinonasal tumors involving the anterior skull base","volume":"26","author":"C Suarez","year":"2004","journal-title":"Head Neck"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1097\/00005537-200208000-00007","article-title":"Orbital preservation in surgical management of sinonasal malignancy","volume":"112","author":"M J Imola","year":"2002","journal-title":"Laryngoscope"},{"issue":"06","key":"ref9","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1097\/01.SCS.0000164332.81428.BA","article-title":"Ethmoido-orbital tumors: our experience","volume":"16","author":"G Iannetti","year":"2005","journal-title":"J Craniofac Surg"},{"issue":"02","key":"ref10","first-page":"123","article-title":"Management of the orbital contents in radical surgery for squamous cell carcinoma of the maxillary sinus","volume":"108","author":"X Wu","year":"1995","journal-title":"Chin Med J (Engl)"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/00005537-199902000-00012","article-title":"Squamous cell carcinoma of the sinonasal tract invading the orbit","volume":"109","author":"R L Carrau","year":"1999","journal-title":"Laryngoscope"},{"issue":"02","key":"ref12","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/(SICI)1097-0347(199803)20:2<97::AID-HED1>3.0.CO;2-Y","article-title":"Craniofacial resection for tumors of the nasal cavity and paranasal sinuses--a 17-year experience","volume":"20","author":"V J Lund","year":"1998","journal-title":"Head Neck"},{"key":"ref13","first-page":"S145","article-title":"ICAR: endoscopic skull-base surgery","volume":"9","author":"E W Wang","year":"2019","journal-title":"Int Forum Allergy Rhinol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1097\/00005537-200208000-00023","article-title":"Sinonasal undifferentiated carcinoma: the search for a better outcome","volume":"112","author":"P Y Musy","year":"2002","journal-title":"Laryngoscope"},{"issue":"01","key":"ref15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0167-8140(94)90005-1","article-title":"Radiation-induced injury to the visual pathway","volume":"30","author":"G L Jiang","year":"1994","journal-title":"Radiother Oncol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.critrevonc.2015.09.009","article-title":"Paranasal sinus cancer","volume":"98","author":"P Bossi","year":"2016","journal-title":"Crit Rev Oncol Hematol"},{"issue":"01","key":"ref17","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1002\/(SICI)1097-0142(19980101)82:1<104::AID-CNCR12>3.0.CO;2-6","article-title":"Squamous cell carcinoma of the maxillary sinus treated with radiation therapy and conservative surgery","volume":"82","author":"J Itami","year":"1998","journal-title":"Cancer"},{"issue":"04","key":"ref18","first-page":"219","article-title":"Multimodality therapy in advanced paranasal sinus carcinoma: superior long-term results","volume":"5","author":"M M Lee","year":"1999","journal-title":"Cancer J Sci Am"},{"issue":"05","key":"ref19","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1002\/cncr.10253","article-title":"Results of multimodality therapy for squamous cell carcinoma of maxillary sinus","volume":"94","author":"K Nibu","year":"2002","journal-title":"Cancer"},{"issue":"11","key":"ref20","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1002\/1097-0142(19921201)70:11<2615::AID-CNCR2820701108>3.0.CO;2-G","article-title":"Potential impact on tumor control and organ preservation with cisplatin and 5-fluorouracil for patients with advanced tumors of the paranasal sinuses and nasal fossa. A prospective pilot study","volume":"70","author":"T Bj\u00f6rk-Eriksson","year":"1992","journal-title":"Cancer"},{"issue":"01","key":"ref21","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1001\/archoto.2010.231","article-title":"Induction chemotherapy for advanced squamous cell carcinoma of the paranasal sinuses","volume":"137","author":"E Y Hanna","year":"2011","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"03","key":"ref22","first-page":"570","article-title":"Induction chemotherapy in head and neck squamous cell carcinoma of the paranasal sinus and nasal cavity: a role in organ preservation","volume":"31","author":"C Y Ock","year":"2016","journal-title":"Korean J Intern Med (Korean Assoc Intern Med)"},{"issue":"08","key":"ref23","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1093\/jjco\/hyw064","article-title":"A clinical study of multimodal treatment for orbital organ preservation in locally advanced squamous cell carcinoma of the nasal cavity and paranasal sinus","volume":"46","author":"N X Chen","year":"2016","journal-title":"Jpn J Clin Oncol"},{"issue":"02","key":"ref24","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/bjophthalmol-2015-306945","article-title":"Invasive fungal disease of the sinus and orbit: a comparison between mucormycosis and Aspergillus","volume":"100","author":"D Trief","year":"2016","journal-title":"Br J Ophthalmol"},{"issue":"09","key":"ref25","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1007\/s00405-015-3733-3","article-title":"Purely endoscopic trans-nasal management of orbital intraconal cavernous haemangiomas: a systematic review of the literature","volume":"273","author":"R Lenzi","year":"2016","journal-title":"Eur Arch Otorhinolaryngol"}],"container-title":["Journal of Neurological Surgery Part B: Skull Base"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1713937.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T10:02:23Z","timestamp":1602842543000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1713937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":25,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2020,10,15]]},"published-print":{"date-parts":[[2020,8]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1713937","relation":{},"ISSN":["2193-6331","2193-634X"],"issn-type":[{"value":"2193-6331","type":"print"},{"value":"2193-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}