{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:51:20Z","timestamp":1740171080109,"version":"3.37.3"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T00:00:00Z","timestamp":1600387200000},"content-version":"vor","delay-in-days":261,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg Rep"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Myasthenia gravis and thymoma are often presented in association with \u223c10% of myasthenic cases having concomitant thymoma. Thymic carcinoma is one of the rarest\/aggressive human epithelial tumors and has no correlation with myasthenia gravis hitherto. Here is provided a clinical case and review of literature on a very rare association of thymic carcinoma (with no sign of thymoma) and myasthenia gravis (antiacetylcholine receptor antibody positive). Two years after thymectomy, clinical evolution was satisfactory. This clinical case elicits hypothesis that thymic carcinoma may be related with myasthenia gravis, what may have good prognostic from oncologic and neurologic perspectives.<\/jats:p>","DOI":"10.1055\/s-0040-1714075","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T23:04:40Z","timestamp":1600470280000},"page":"e33-e36","source":"Crossref","is-referenced-by-count":0,"title":["Myasthenia Gravis Related to Thymic Carcinoma: A Case Study"],"prefix":"10.1055","volume":"09","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2484-756X","authenticated-orcid":false,"given":"Daniel Thomas Pereira","family":"Lopes","sequence":"additional","affiliation":[{"name":"Neurology Departament, Hospital Santa Marcelina, Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samila Marissa Pinheiro","family":"Gomes","sequence":"additional","affiliation":[{"name":"Neurology Departament, Hospital Santa Marcelina, Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheila Aparecida Coelho","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Pathology Departament, Universidade de Sao Paulo Hospital das Clinicas, Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Pereira","family":"Frassetto","sequence":"additional","affiliation":[{"name":"Pathology Departament, Universidade de Sao Paulo Hospital das Clinicas, Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Henrique Martins Arruda","family":"Sampaio","sequence":"additional","affiliation":[{"name":"Neurology Departament, Hospital Santa Marcelina, Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiane Araujo Martins","family":"Moreno","sequence":"additional","affiliation":[{"name":"Neurology Departament, Hospital Santa Marcelina, Sao Paulo, S\u00e3o Paulo, Brazil"},{"name":"Neurology Departament, Universidade de Sao Paulo Hospital das Clinicas, Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Sheila Guimar\u00e3es","family":"Rocha","sequence":"additional","affiliation":[{"name":"Neurology Departament, Hospital Santa Marcelina, Sao Paulo, S\u00e3o Paulo, Brazil"},{"name":"Neurology Departament, Faculdade Santa Marcelina Curso de Medicina, Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Paula","family":"Estephan","sequence":"additional","affiliation":[{"name":"Neurology Departament, Hospital Santa Marcelina, Sao Paulo, S\u00e3o Paulo, Brazil"},{"name":"Neurology Departament, Faculdade de Medicina da Universidade de S\u00e3o Paulo, Sao Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,9,18]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jaut.2013.12.011","article-title":"Myasthenia gravis: a comprehensive review of immune dysregulation and etiological mechanisms","volume":"52","author":"S Berrih-Aknin","year":"2014","journal-title":"J Autoimmun"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1055\/s-0037-1602832","article-title":"The increasing genetic and phenotypical diversity of congenital myasthenic syndromes","volume":"48","author":"G McMacken","year":"2017","journal-title":"Neuropediatrics"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1017\/cjn.2016.322","article-title":"Nonlethal CHRNA1-related congenital myasthenic syndrome with a homozygous null mutation","volume":"44","author":"O Abath 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