{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T13:32:58Z","timestamp":1790429578071,"version":"4.1.0"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This is the first study to show a stepwise increase in venous thrombotic events according to COVID-19 coagulopathy (COVID-19-associated hemostatic abnormalities [CAHA]) staging and lung injuries assessed by chest computed tomography. Excess mortality and\/or transfer to intensive care unit according to CAHA staging.<\/jats:p>","DOI":"10.1055\/s-0040-1715836","type":"journal-article","created":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T22:38:29Z","timestamp":1598827109000},"page":"1716-1719","source":"Crossref","is-referenced-by-count":11,"title":["Staging Severity of COVID-19 according to Hemostatic Abnormalities (CAHA Score)"],"prefix":"10.1055","volume":"120","author":[{"given":"Benjamin","family":"Marchandot","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonin","family":"Trimaille","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Curtiaud","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrien","family":"Carmona","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3722-2921","authenticated-orcid":false,"given":"Kensuke","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"},{"name":"INSERM (French National Institute of Health and Medical Research), Regenerative Nanomedicine, FMTS, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chisato","family":"Sato","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"},{"name":"INSERM (French National Institute of Health and Medical Research), Regenerative Nanomedicine, FMTS, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Leonard-Lorant","sequence":"additional","affiliation":[{"name":"Radiology Department, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Sattler","sequence":"additional","affiliation":[{"name":"Department Laboratory Haematology, Centre for Thrombosis and Haemostasis, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lelia","family":"Grunebaum","sequence":"additional","affiliation":[{"name":"Department Laboratory Haematology, Centre for Thrombosis and Haemostasis, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micka\u00ebl","family":"Ohana","sequence":"additional","affiliation":[{"name":"Radiology Department, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Ohlmann","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Jesel","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"},{"name":"INSERM (French National Institute of Health and Medical Research), Regenerative Nanomedicine, FMTS, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Morel","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital, Strasbourg, France"},{"name":"INSERM (French National Institute of Health and Medical Research), Regenerative Nanomedicine, FMTS, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,8,30]]},"reference":[{"key":"ref1","first-page":"201561","article-title":"Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to D-dimer levels","author":"I Leonard-Lorant","year":"2020","journal-title":"Radiology"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1055\/s-0040-1710018","article-title":"COVID-19-related severe hypercoagulability in patients admitted to intensive care unit for acute respiratory failure","volume":"120","author":"L Spiezia","year":"2020","journal-title":"Thromb Haemost"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1055\/s-0040-1710019","article-title":"Prevention and treatment of venous thromboembolism associated with coronavirus disease 2019 infection: a consensus statement before guidelines","volume":"120","author":"Z Zhai","year":"2020","journal-title":"Thromb Haemost"},{"issue":"06","key":"ref4","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1055\/s-0040-1710317","article-title":"Hypercoagulation and antithrombotic treatment in coronavirus 2019: a new challenge","volume":"120","author":"F Violi","year":"2020","journal-title":"Thromb Haemost"},{"issue":"05","key":"ref5","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/rth2.12372","article-title":"A proposal for staging COVID-19 coagulopathy","volume":"4","author":"J Thachil","year":"2020","journal-title":"Res Pract Thromb Haemost"},{"key":"ref6","first-page":"1","article-title":"COVID-19 patients and the radiology department - advice from the European Society of Radiology (ESR) and the European Society of Thoracic Imaging (ESTI)","author":"M P Revel","year":"2020","journal-title":"Eur Radiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(20)30566-3","article-title":"Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study","volume":"395","author":"F Zhou","year":"2020","journal-title":"Lancet"},{"issue":"05","key":"ref8","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1055\/s-0040-1709650","article-title":"D-dimer is associated with severity of coronavirus disease 2019: a pooled analysis","volume":"120","author":"G Lippi","year":"2020","journal-title":"Thromb Haemost"},{"issue":"07","key":"ref9","first-page":"E437","article-title":"Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia","volume":"2","author":"D McGonagle","year":"2020","journal-title":"Lancet"},{"issue":"07","key":"ref10","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1111\/jth.14854","article-title":"The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome","volume":"18","author":"M Ranucci","year":"2020","journal-title":"J Thromb Haemost"},{"issue":"02","key":"ref11","first-page":"95","article-title":"Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis","volume":"22","author":"F Ciceri","year":"2020","journal-title":"Crit Care Resusc"},{"issue":"06","key":"ref12","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1111\/jth.14844","article-title":"Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19","volume":"18","author":"M Dolhnikoff","year":"2020","journal-title":"J Thromb Haemost"},{"issue":"02","key":"ref13","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1056\/NEJMoa2015432","article-title":"Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19","volume":"383","author":"M Ackermann","year":"2020","journal-title":"N Engl J Med"},{"issue":"07","key":"ref14","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1055\/s-0040-1713152","article-title":"Pharmacological agents targeting thromboinflammation in COVID-19: review and implications for future research","volume":"120","author":"B Bikdeli","year":"2020","journal-title":"Thromb Haemost"}],"container-title":["Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1715836.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T23:50:52Z","timestamp":1608767452000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1715836"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,30]]},"references-count":14,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020,12,23]]},"published-print":{"date-parts":[[2020,12]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1715836","relation":{},"ISSN":["0340-6245","2567-689X"],"issn-type":[{"value":"0340-6245","type":"print"},{"value":"2567-689X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,30]]}}}