{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:55:32Z","timestamp":1780102532380,"version":"3.54.0"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T00:00:00Z","timestamp":1598745600000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\nIntroduction\u2003Posttraumatic brachial plexus injuries are devastating, as the brain and spinal cord are disconnected from the upper limb. Restoration of elbow flexion has been widely recognized as the primary objective of nerve reconstruction. In the absence of utilizable (ruptured) root stumps in the neck, one has recourse only to nerve transfers. The direct transfer of intercostal nerves to the musculocutaneous nerve is one of the techniques that has been commonly employed over the past four decades. However, the outcomes of this procedure cited in the literature have varied considerably. The patient\u2019s age and the delay from the accident to surgery have been known to affect the results of nerve reconstruction operations. The authors present a study of the effect of these parameters on intercostal nerve transfers.<\/jats:p><jats:p>\nMethods\u2003The data of 232 patients with total and near-total brachial plexus injuries treated by the senior author between April 1995 and December 2015 was examined. Intercostal nerve transfers were used for the restoration of biceps function in each of these patients. The outcomes were tabulated, and the correlation with the age and the delay before surgery was examined.<\/jats:p><jats:p>\nResults\u2003The strength of the biceps regained was better in patients younger than 30 years old and those operated upon earlier than 6 months from the accident. The differences in outcomes were found to be statistically significant (p = 0.001 for preoperative delay and p &lt; 0.005 for the patient\u2019s age).<\/jats:p><jats:p>\nConclusion\u2003The results give clear proof of the significant effect of the age and preoperative delay on the outcomes of intercostal nerve transfers for restoration of biceps function. These findings can serve as pointers to help the surgeon in choosing the method of nerve reconstruction in a given case.<\/jats:p>","DOI":"10.1055\/s-0040-1716081","type":"journal-article","created":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T22:41:27Z","timestamp":1598827287000},"page":"260-265","source":"Crossref","is-referenced-by-count":13,"title":["The Effect of Age and the Delay before Surgery on the Outcomes of Intercostal Nerve Transfers to the Musculocutaneous Nerve: A Retrospective Study of 232 Cases of Posttraumatic Total and Near-total Brachial Plexus Injuries"],"prefix":"10.1055","volume":"53","author":[{"given":"Anil","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Departmentof Brachial Plexus, Deenanath Mangeshkar Hospital and Research Center, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Departmentof Brachial Plexus, Deenanath Mangeshkar Hospital and Research Center, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0376-8002","authenticated-orcid":false,"given":"Pablo","family":"Zancolli","sequence":"additional","affiliation":[{"name":"Departmentof Hand Surgery, Fundacion Favaloro, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul Rodriguez","family":"Martinez","sequence":"additional","affiliation":[{"name":"Department of Brachial Plexus and Hand Surgery, Cl\u00ednica Mielina Plexo Braquial, Hospital Real San Jos\u00e9, Guadalajara, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Clifton","sequence":"additional","affiliation":[{"name":"Department of Brachial Plexus and Hand Surgery, Cl\u00ednica Mielina Plexo Braquial, Hospital Real San Jos\u00e9, Guadalajara, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek","family":"El-Gammal","sequence":"additional","affiliation":[{"name":"Departmentof Brachial Plexus, Assiut University, Assiut, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Muset","sequence":"additional","affiliation":[{"name":"Departmentof Brachial Plexus and Hand Surgery, Muset Institute, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,8,30]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"382","DOI":"10.5435\/00124635-200510000-00003","article-title":"Adult traumatic brachial plexus injuries","volume":"13","author":"A Y Shin","year":"2005","journal-title":"J Am Acad Orthop Surg"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.hcl.2004.09.007","article-title":"Planning brachial plexus surgery: treatment 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Tsuyama","year":"1972","journal-title":"Exerpta Medica"},{"issue":"02","key":"ref10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1053\/jhsu.2001.21518","article-title":"Results of nerve transfer techniques for restoration of shoulder and elbow function in the context of a meta-analysis of the English literature","volume":"26","author":"G A Merrell","year":"2001","journal-title":"J Hand Surg Am"},{"issue":"05","key":"ref11","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/0363-5023(92)90451-T","article-title":"Intercostal nerve transfer of the musculocutaneous nerve in avulsed brachial plexus injuries: evaluation of 66 patients","volume":"17","author":"D C Chuang","year":"1992","journal-title":"J Hand Surg Am"},{"issue":"06","key":"ref12","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/S0363-5023(89)80047-4","article-title":"Direct nerve crossing with the intercostal nerve to treat avulsion injuries of the brachial 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