{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:57:36Z","timestamp":1790377056200,"version":"4.1.0"},"reference-count":4,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T00:00:00Z","timestamp":1598745600000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Reconstruction of long tracheal defects still proves to be a challenge. Free fasciocutaneous flaps with cartilaginous struts or an allotransplant trachea have been reported but not been widely performed. This article reports with the experience of using a tracheal allotransplant in such a defect.<\/jats:p><jats:p>A 43-year-old lady presented with adenoid cystic carcinoma involving the entire trachea from subglottic area up to the carina, leading to a life-threatening airway occlusion. After preliminary stenting, allotransplant trachea obtained from a brain-dead individual was revascularized in the forearm of the patient after mechanical decellularization to reduce the immune load and fulfil the need for immunosuppression in the background of active cancer. Subsequently, the trachea and larynx were resected. The vascularized neotrachea was transferred successfully into the neck. The patient did well initially but succumbed to a fatal hemorrhage due to innominate vein aneurysmal rupture on the 22nd day after the transplant.<\/jats:p><jats:p>The technical details of resection, fabrication of the neotrachea, its transfer, and the lessons learnt in this tracheal allotransplant are described.<\/jats:p>","DOI":"10.1055\/s-0040-1716420","type":"journal-article","created":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T22:41:27Z","timestamp":1598827287000},"page":"306-308","source":"Crossref","is-referenced-by-count":8,"title":["Tracheal Allotransplantation\u2013Lessons Learned"],"prefix":"10.1055","volume":"53","author":[{"given":"Subramania","family":"Iyer","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Oncology and Plastic Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"},{"name":"Department of Plastic and Reconstructive Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narayana","family":"Subramaniam","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Oncology and Plastic Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivakumar","family":"Vidhyadharan","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Oncology and Plastic Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnakumar","family":"Thankappan","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Oncology and Plastic Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Balasubramanian","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Oncology and Plastic Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balasubramanian K.","family":"R.","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kishore","family":"Purushottaman","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janarthanan","family":"Ramu","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachariah","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,8,30]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/S0022-5223(95)70279-2","article-title":"Postintubation tracheal stenosis. Treatment and results","volume":"109","author":"H C Grillo","year":"1995","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1056\/NEJMoa0810653","article-title":"Tracheal allotransplantation after withdrawal of immunosuppressive therapy","volume":"362","author":"P Delaere","year":"2010","journal-title":"N Engl J Med"},{"issue":"02","key":"ref3","first-page":"74","article-title":"Treatment outcome of resected and nonresected primary adenoid cystic carcinoma of the lung","volume":"8","author":"T Kanematsu","year":"2002","journal-title":"Ann Thorac Cardiovasc Surg"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.bjps.2012.07.008","article-title":"Reconstruction of the (Crico) trachea for malignancy in the virgin and irradiated neck","volume":"65","author":"S Ch\u2019ng","year":"2012","journal-title":"J Plast Reconstr Aesthet Surg"}],"container-title":["Indian Journal of Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1716420.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T23:42:18Z","timestamp":1598917338000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1716420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":4,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2020,8,31]]},"published-print":{"date-parts":[[2020,8]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1716420","relation":{},"ISSN":["0970-0358","1998-376X"],"issn-type":[{"value":"0970-0358","type":"print"},{"value":"1998-376X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}