{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T02:03:37Z","timestamp":1783735417080,"version":"3.55.0"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"07","funder":[{"name":"National Institutes of Health's National Center for Advancing Translational Sciences","award":["UL1TR001422"],"award-info":[{"award-number":["UL1TR001422"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to estimate whether there is an association between the predicted probability of vaginal birth after cesarean delivery (VBAC) and the occurrence of obstetric anal sphincter injuries (OASIS).<\/jats:p><jats:p>\n            Study Design\u2003This was a single-site retrospective cohort study of all women with a singleton vaginal birth after a previous cesarean section between January 2011 and December 2016. Women were divided into four ordinal groupings by the predicted probability of achieving vaginal birth after cesarean using the Maternal\u2013Fetal Medicine Units Network VBAC calculator (less than 41%, 40.1\u201360%, 60.1\u201380%, and greater than 80%). The primary outcome was OASIS, defined as a 3rd or 4th degree perineal laceration. Bivariable and multivariable analyses were used to examine the association between predicted VBAC probability and OASIS.<\/jats:p><jats:p>\n            Results\u2003In total, 1,411 women met inclusion criteria and 73 (5.2%) sustained OASIS. The median predicted probability of VBAC was lower in women with OASIS compared with those without OASIS (60% [interquartile range {IQR}: 48\u201370%] vs. 66% (IQR: 52\u201380%), p\u2009=\u20090.02]. On bivariable and multivariable logistic regression, predicted probability of VBAC was associated with increased odds of OASIS (less than 41% probability: adjusted odds ratio [aOR]: 3.18, 95% confidence interval [CI]: 0.90\u201311.21; 41\u201360% probability: aOR: 3.76, 95% CI: 1.34\u201310.57; 61\u201380% probability aOR: 3.47, 95% CI: 1.25\u20139.69) relative to women with a predicted probability of VBAC of greater than 80%.<\/jats:p><jats:p>\n            Conclusion\u2003Having a lower predicted probability of VBAC is associated with an increased risk of OASIS at the time of a VBAC relative to those with greater than 80% predicted probability. Incorporation of this aspect of maternal morbidity may inform risk-stratification at the time of trial of labor after cesarean, as well as the choice of performing an operative vaginal delivery.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0040-1717099","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T23:01:51Z","timestamp":1601420511000},"page":"750-758","source":"Crossref","is-referenced-by-count":4,"title":["Is there an Association between Vaginal Birth after Cesarean Prediction and Obstetric Anal Sphincter Injury?"],"prefix":"10.1055","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7223-0487","authenticated-orcid":false,"given":"Oluwateniola","family":"Brown","sequence":"additional","affiliation":[{"name":"Division of Female Pelvic Medicine and Reconstructive Surgery, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Luchristt","sequence":"additional","affiliation":[{"name":"Division of Female Pelvic Medicine and Reconstructive Surgery, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily S.","family":"Miller","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahati","family":"Pidaparti","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Geynisman-Tan","sequence":"additional","affiliation":[{"name":"Division of Female Pelvic Medicine and Reconstructive Surgery, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Kenton","sequence":"additional","affiliation":[{"name":"Division of Female Pelvic Medicine and Reconstructive Surgery, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Lewicky-Gaupp","sequence":"additional","affiliation":[{"name":"Division of Female Pelvic Medicine and Reconstructive Surgery, Northwestern University, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,9,29]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1097\/01.AOG.0000259312.36053.02","article-title":"Development of a nomogram for prediction of vaginal birth after cesarean delivery","volume":"109","author":"W A Grobman","year":"2007","journal-title":"Obstet Gynecol"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1097\/AOG.0000000000000744","article-title":"Validation of a vaginal birth after cesarean delivery prediction model in women with two prior cesarean deliveries","volume":"125","author":"T D Metz","year":"2015","journal-title":"Obstet Gynecol"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"513.e1","DOI":"10.1016\/j.ajog.2016.05.039","article-title":"A prediction model of vaginal birth after cesarean in the preterm period","volume":"215","author":"A H Mardy","year":"2016","journal-title":"Am J Obstet Gynecol"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"56.e1","DOI":"10.1016\/j.ajog.2008.06.039","article-title":"Can a prediction model for vaginal birth after cesarean also predict the probability of morbidity related to a trial of labor?","volume":"200","author":"W A Grobman","year":"2009","journal-title":"Am J Obstet Gynecol"},{"issue":"06","key":"ref5","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1016\/j.ajog.2003.09.030","article-title":"Fecal and urinary incontinence after vaginal delivery with anal sphincter disruption in an obstetrics unit in the United States","volume":"189","author":"D E Fenner","year":"2003","journal-title":"Am J Obstet Gynecol"},{"issue":"04","key":"ref6","doi-asserted-by":"crossref","first-page":"303.e1","DOI":"10.1016\/j.ajog.2012.08.019","article-title":"Risk of surgically managed pelvic floor dysfunction in relation to age at first delivery","volume":"207","author":"\u00c5 Leijonhufvud","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/AOG.0b013e318240df4f","article-title":"Pelvic floor disorders after vaginal birth: effect of episiotomy, perineal laceration, and operative birth","volume":"119","author":"V L Handa","year":"2012","journal-title":"Obstet Gynecol"},{"issue":"05","key":"ref8","doi-asserted-by":"crossref","first-page":"423.e1","DOI":"10.1016\/j.ajog.2014.01.032","article-title":"Pelvic pain and mode of delivery","volume":"210","author":"J L Blomquist","year":"2014","journal-title":"Am J Obstet Gynecol"},{"issue":"05","key":"ref9","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1097\/AOG.0000000000000833","article-title":"Wound complications after obstetric anal sphincter injuries","volume":"125","author":"C Lewicky-Gaupp","year":"2015","journal-title":"Obstet Gynecol"},{"issue":"02","key":"ref10","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/AOG.0000000000002444","article-title":"Risk factors for the development of obstetric anal sphincter injuries in modern obstetric practice","volume":"131","author":"O Ramm","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"05","key":"ref11","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1067\/mob.2002.126977","article-title":"Risk factors associated with anal sphincter tear: a comparison of primiparous patients, vaginal births after cesarean deliveries, and patients with previous vaginal delivery","volume":"187","author":"H E Richter","year":"2002","journal-title":"Am J Obstet Gynecol"},{"issue":"08","key":"ref12","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1007\/s00192-012-2006-6","article-title":"A prior cesarean section and incidence of obstetric anal sphincter injury","volume":"24","author":"S R\u00e4is\u00e4nen","year":"2013","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"12","key":"ref13","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1111\/1471-0528.12706","article-title":"Are women having a vaginal birth after a previous caesarean delivery at increased risk of anal sphincter injury?","volume":"121","author":"M P Hehir","year":"2014","journal-title":"BJOG"},{"issue":"03","key":"ref14","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ijgo.2015.06.025","article-title":"Obstetric anal sphincter injury rates among primiparous women with different modes of vaginal delivery","volume":"131","author":"A J Ampt","year":"2015","journal-title":"Int J Gynaecol Obstet"},{"issue":"04","key":"ref15","doi-asserted-by":"crossref","first-page":"344.e1","DOI":"10.1016\/j.ajog.2006.10.893","article-title":"Risk factors for primary and subsequent anal sphincter lacerations: a comparison of cohorts by parity and prior mode of delivery","volume":"196","author":"J L Lowder","year":"2007","journal-title":"Am J Obstet Gynecol"},{"issue":"01","key":"ref16","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ijgo.2013.09.034","article-title":"Risk factors for severe perineal lacerations during childbirth","volume":"125","author":"V Pergialiotis","year":"2014","journal-title":"Int J Gynaecol Obstet"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1186\/s12884-015-0689-7","article-title":"Birth position and obstetric anal sphincter injury: a population-based study of 113 000 spontaneous births","volume":"15","author":"C Elvander","year":"2015","journal-title":"BMC Pregnancy Childbirth"},{"issue":"01","key":"ref18","doi-asserted-by":"crossref","first-page":"59.e1","DOI":"10.1016\/j.ajog.2013.08.043","article-title":"Modifiable risk factors of obstetric anal sphincter injury in primiparous women: a population-based cohort study","volume":"210","author":"H Jang\u00f6","year":"2014","journal-title":"Am J Obstet Gynecol"},{"issue":"01","key":"ref19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00192-015-2795-5","article-title":"Risk factors for severe obstetric perineal lacerations","volume":"27","author":"M Vale de Castro Monteiro","year":"2016","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"06","key":"ref20","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/s00192-015-2893-4","article-title":"Risk factors for recurrent obstetric anal sphincter injury (rOASI): a systematic review and meta-analysis","volume":"27","author":"S Jha","year":"2016","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"01","key":"ref21","first-page":"CD000081","article-title":"Episiotomy for vaginal birth","author":"G Carroli","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"issue":"03","key":"ref22","doi-asserted-by":"crossref","first-page":"310.e1","DOI":"10.1016\/j.ajog.2016.02.041","article-title":"Predicting obstetric anal sphincter injuries in a modern obstetric population","volume":"215","author":"M R Meister","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1186\/1756-0500-7-471","article-title":"Can the risk of obstetric anal sphincter injuries (OASIs) be predicted using a risk-scoring system?","volume":"7","author":"K C McPherson","year":"2014","journal-title":"BMC Res Notes"},{"issue":"08","key":"ref24","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1111\/j.1471-0528.2005.00652.x","article-title":"Risk scoring system for prediction of obstetric anal sphincter injury","volume":"112","author":"A Williams","year":"2005","journal-title":"BJOG"},{"issue":"03","key":"ref25","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/AOG.0000000000001533","article-title":"Simulation training for forceps-assisted vaginal delivery and rates of maternal perineal trauma","volume":"128","author":"D R Gossett","year":"2016","journal-title":"Obstet Gynecol"},{"issue":"10","key":"ref26","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1007\/s00192-019-03978-x","article-title":"Risk factors for obstetric anal sphincter injuries at vaginal birth after caesarean: a retrospective cohort study","volume":"30","author":"J C D'Souza","year":"2019","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"01","key":"ref27","doi-asserted-by":"crossref","first-page":"e146","DOI":"10.1097\/SPV.0000000000000867","article-title":"Risks and associations of third- and fourth-degree lacerations: an urban single center experience","volume":"27","author":"K Chiu","year":"2021","journal-title":"Female Pelvic MedReconst Surgery"},{"issue":"02","key":"ref28","doi-asserted-by":"crossref","first-page":"e110","DOI":"10.1097\/AOG.0000000000003078","article-title":"ACOG practice bulletin no. 205: vaginal birth after cesarean delivery","volume":"133","author":"American College of Obstetricians and Gynecologists' Committee on Practice Bulletins\u2014Obstetrics","year":"2019","journal-title":"Obstet Gynecol"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1717099.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T23:06:14Z","timestamp":1656975974000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1717099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,29]]},"references-count":28,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2022,7,4]]},"published-print":{"date-parts":[[2022,5]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1717099","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,29]]}}}