{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T10:14:13Z","timestamp":1779185653058,"version":"3.51.4"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>\n            Objective\u2003The study aimed to compare the quantitative blood loss (QBL) and hemorrhage-related outcomes of pregnant women with and without a coronavirus disease 2019 (COVID-19) diagnosis.<\/jats:p><jats:p>\n            Study Design\u2003This retrospective cohort study of all live deliveries at Boston Medical Center between April 1, 2020 and July 22, 2020 compares the outcomes of pregnant women with a laboratory-confirmed COVID-19 positive diagnosis and pregnant women without COVID-19. The primary outcomes are QBL and obstetric hemorrhage. The secondary outcomes analyzed were a maternal composite outcome that consisted of obstetric hemorrhage, telemetry-level (intermediate care unit) or intensive care unit, transfusion, length of stay greater than 5 days, or intraamniotic infection, and individual components of the maternal composite outcome. Groups were compared using Student's t-test, Chi-squared tests, or Fisher's exact. Logistic regression was used to adjust for confounding variables.<\/jats:p><jats:p>\n            Results\u2003Of 813 women who delivered a live infant between April 1 and July 22, 2020, 53 women were diagnosed with COVID-19 on admission to the hospital. Women with a COVID-19 diagnosis at their time of delivery were significantly more likely to identify as a race other than white (p\u2009=\u20090.01), to deliver preterm (p\u2009=\u20090.05), to be diagnosed with preeclampsia with severe features (p\u2009&lt;\u20090.01), and to require general anesthesia (p\u2009&lt;\u20090.01). Women diagnosed with COVID-19 did not have a significantly higher QBL (p\u2009=\u20090.64). COVID-19 positive pregnant patients had no increased adjusted odds of obstetric hemorrhage (adjusted odds ratio [aOR]: 0.41, 95% confidence interval [CI]: 0.17\u20131.04) and no increased adjusted odds of the maternal morbidity composite (aOR: 0.98, 95% CI: 0.50\u20131.93) when compared with those without a diagnosis of COVID-19.<\/jats:p><jats:p>\n            Conclusion\u2003Pregnant women with COVID-19 diagnosis do not have increased risk for obstetric hemorrhage, increased QBL or risk of maternal morbidity compared with pregnant women without a COVID-19 diagnosis. Further research is needed to describe the impact of a COVID-19 diagnosis on maternal hematologic physiology and pregnancy outcomes.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0040-1718403","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T23:01:51Z","timestamp":1601420511000},"page":"1411-1416","source":"Crossref","is-referenced-by-count":29,"title":["Obstetric Hemorrhage Risk Associated with Novel COVID-19 Diagnosis from a Single-Institution Cohort in the United States"],"prefix":"10.1055","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5177-8109","authenticated-orcid":false,"given":"Michelle J.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Boston Medical Center, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Schapero","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Boston Medical Center, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Iverson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Boston Medical Center, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina D.","family":"Yarrington","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Boston Medical Center, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,9,29]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1111\/jth.14768","article-title":"Abnormal coagulation parameters are associated 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