{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T05:24:07Z","timestamp":1783401847443,"version":"3.54.6"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to review the feasibility of nasal high-frequency oscillatory ventilation (NHFOV) in preventing reintubation in preterm infants.<\/jats:p><jats:p>\n            Study Design\u2003This is a retrospective cohort study of all premature newborn infants placed on NHFOV in a single-center neonatal intensive care unit.<\/jats:p><jats:p>\n            Results\u2003Twenty-seven patients (birth weight: 765\u2009\u00b1\u2009186\u2009g, gestational age: 28\u2009\u00b1\u20092 weeks) were commenced on NHFOV on 32 occasions. NHFOV was used immediately postextubation as the primary mode of noninvasive ventilation (NIV; prophylaxis) in 10 of 32 occasions and as \u201crescue\u201d (failure of NCPAP or biphasic CPAP) in 22 of 32 occasions. Treatment with NHFOV was successful in 22 occasions (69%) while on 10 occasions (31%) reintubation was required within 72\u2009hours. In the rescue group, there was significant reduction in the mean (standard deviation [SD]) number of apneas (0.9\u2009\u00b1\u20091.07 vs. 0.3\u2009\u00b1\u20090.29, p\u2009&lt;\u20090.005), but there were no significant changes in the PCO2 level (52 [\u2009\u00b1\u2009\u20099.8] vs. 52 [\u2009\u00b1\u2009\u20098.6] mm Hg, p\u2009=\u20090.8), or the FiO2 requirement (0.39\u2009\u00b1\u20090.19 vs. 0.33\u2009\u00b1\u20090.10, p\u2009=\u20090.055) before and after commencing NHFOV, respectively.<\/jats:p><jats:p>\n            Conclusion\u2003The use of NHFOV is feasible as a prophylactic or rescue mode of NIV following extubation and was associated with decrease in the number of apneas without significant changes in PCO2 or oxygen requirements. A well-designed randomized control trial is needed to determine the indications, clinical outcomes, and safety of this treatment modality.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0040-1718738","type":"journal-article","created":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T22:53:16Z","timestamp":1603147996000},"page":"666-670","source":"Crossref","is-referenced-by-count":11,"title":["Noninvasive High-Frequency Oscillatory Ventilation: A Retrospective Chart Review"],"prefix":"10.1055","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0630-7321","authenticated-orcid":false,"given":"Yaser A.H.","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health, Section of Neonatology, University of Manitoba, Winnipeg, Manitoba, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary M.","family":"Seshia","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health, Section of Neonatology, University of Manitoba, Winnipeg, Manitoba, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebtihal","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health, Section of Neonatology, University of Manitoba, Winnipeg, Manitoba, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben","family":"Alvaro","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health, Section of Neonatology, University of Manitoba, Winnipeg, Manitoba, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,10,19]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1056\/NEJMoa1214533","article-title":"A trial comparing noninvasive ventilation strategies in preterm infants","volume":"369","author":"H Kirpalani","year":"2013","journal-title":"N Engl J Med"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1542\/peds.2010-0922","article-title":"Noninvasive ventilation for respiratory distress syndrome: a randomized controlled trial","volume":"127","author":"J Meneses","year":"2011","journal-title":"Pediatrics"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/j.1651-2227.2007.00263.x","article-title":"Nasal CPAP has become an indispensable part of the primary treatment of newborns with respiratory distress syndrome","volume":"96","author":"H Verder","year":"2007","journal-title":"Acta Paediatr"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"F61","DOI":"10.1136\/fn.79.1.F61","article-title":"Nasal high frequency ventilation in neonates with moderate respiratory insufficiency","volume":"79","author":"M van der Hoeven","year":"1998","journal-title":"Arch Dis Child Fetal Neonatal 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trial","volume":"37","author":"A Mukerji","year":"2017","journal-title":"J Perinatol"},{"issue":"08","key":"ref8","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1002\/ppul.23755","article-title":"Noninvasive high-frequency oscillatory ventilation versus nasal continuous positive airway pressure in preterm infants with moderate-severe respiratory distress syndrome: A preliminary report","volume":"52","author":"X-W Zhu","year":"2017","journal-title":"Pediatr Pulmonol"},{"issue":"02","key":"ref9","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1055\/s-0034-1381317","article-title":"Use of noninvasive high-frequency ventilation in the neonatal intensive care unit: a retrospective review","volume":"30","author":"A Mukerji","year":"2015","journal-title":"Am J Perinatol"},{"issue":"04","key":"ref10","doi-asserted-by":"crossref","first-page":"F1","DOI":"10.1136\/archdischild-2017-313190","article-title":"Non-invasive high-frequency oscillatory ventilation in preterm infants: a randomised controlled cross-over trial","volume":"103","author":"D Klotz","year":"2018","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"01","key":"ref11","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12931-019-1023-0","article-title":"Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: a meta-analysis of randomized controlled trials","volume":"20","author":"J Li","year":"2019","journal-title":"Respir Res"},{"issue":"04","key":"ref12","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00431-014-2419-y","article-title":"Nasal high-frequency oscillation ventilation in neonates: a survey in five European countries","volume":"174","author":"H S Fischer","year":"2015","journal-title":"Eur J Pediatr"},{"issue":"03","key":"ref13","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/apa.13644","article-title":"Survey of noninvasive respiratory support practices in Canadian neonatal 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