{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T00:19:51Z","timestamp":1793751591901,"version":"4.6.1"},"reference-count":151,"publisher":"Georg Thieme Verlag KG","issue":"02\/03","funder":[{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"crossref","award":["R00NR017191"],"award-info":[{"award-number":["R00NR017191"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","award":["R01HD094842"],"award-info":[{"award-number":["R01HD094842"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Reprod Med"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Adenomyosis, characterized by the presence of endometrial glands and stroma within the myometrium, can have a substantial impact on the quality of women's lives. Despite this, the epidemiologic research on this condition lags considerably behind that of other noncancerous reproductive health conditions. The lack of progress and knowledge is due in part to the challenges in designing valid epidemiologic studies, since the diagnosis of adenomyosis historically has been limited to the examination of uterine specimens from hysterectomy. This review describes the available data on the frequency of this condition and the epidemiologic investigation thus far into the risk factors for disease\u2014highlighting the methodologic and inference challenges primarily around study sample selection. We conclude with providing recommendations for approaches to future epidemiologic study that capitalize on the advancements in imaging technology to detect adenomyosis and provide a fuller picture of the occurrence and risk factors for disease.<\/jats:p>","DOI":"10.1055\/s-0040-1718920","type":"journal-article","created":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T23:53:16Z","timestamp":1603756396000},"page":"089-107","source":"Crossref","is-referenced-by-count":181,"title":["Epidemiology of Adenomyosis"],"prefix":"10.1055","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9598-8776","authenticated-orcid":false,"given":"Kristen","family":"Upson","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey A.","family":"Missmer","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, Michigan"},{"name":"Department of Obstetrics, Gynecology, and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, Michigan"},{"name":"Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,10,26]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.jmig.2019.11.013","article-title":"Classification and reporting systems for adenomyosis","volume":"27","author":"M G Munro","year":"2020","journal-title":"J Minim Invasive Gynecol"},{"key":"ref2","first-page":"1541","article-title":"The elusive adenomyosis of the uterus. 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