{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,10,22]],"date-time":"2022-10-22T20:30:23Z","timestamp":1666470623914},"reference-count":46,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Neurol"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Status epilepticus is one of the most common neurological emergencies and is likely to have increasing prevalence in coming years given an aging \u201cbaby boomer\u201d population in the United States. Because status epilepticus is associated with significant morbidity and mortality, identification and treatment are paramount. Care should be taken to exclude nonorganic mimics and infectious and metabolic causes. Status epilepticus can be classified into stages with associated recommendations for escalation in therapy, increasing from push-dose benzodiazepines to continuous anesthetic infusions and other nontraditional therapies. Concurrent electroencephalogram monitoring helps to identify, localize, and assess resolution of ictal patterns alongside antiseizure drug administration. A protocol is proposed for the management of status epilepticus in a step-wise fashion.<\/jats:p>","DOI":"10.1055\/s-0040-1719112","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T23:56:18Z","timestamp":1605138978000},"page":"652-660","source":"Crossref","is-referenced-by-count":2,"title":["Status Epilepticus: Work-Up and Management in Adults"],"prefix":"10.1055","volume":"40","author":[{"given":"Assia","family":"Meziane-Tani","sequence":"additional","affiliation":[{"name":"Division of Neurocritical Care, Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Foreman","sequence":"additional","affiliation":[{"name":"Division of Neurocritical Care, Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moshe A.","family":"Mizrahi","sequence":"additional","affiliation":[{"name":"Division of Neurocritical Care, Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,11,11]]},"reference":[{"key":"ref1","first-page":"199","article-title":"Status epilepticus","volume":"16","author":"E Waterhouse","year":"2010","journal-title":"Continuum (Minneap Minn)"},{"issue":"10","key":"ref2","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1111\/epi.13121","article-title":"A definition and classification of status epilepticus--Report of the ILAE Task Force on Classification of Status Epilepticus","volume":"56","author":"E Trinka","year":"2015","journal-title":"Epilepsia"},{"issue":"08","key":"ref3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3390\/jcm5080071","article-title":"Status epilepticus: epidemiology and public health needs","volume":"5","author":"S S\u00e1nchez","year":"2016","journal-title":"J Clin Med"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/S1474-4422(06)70374-X","article-title":"Status epilepticus: pathophysiology and management in adults","volume":"5","author":"J W Chen","year":"2006","journal-title":"Lancet Neurol"},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-319-31230-9","volume-title":"Continuous EEG Monitoring Principles and Practice","author":"A M Husain","year":"2017"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/978-3-319-58200-9_23","volume-title":"Continuous EEG monitoring for status epilepticus","author":"M B Dhakar","year":"2018","edition":"2nd ed"},{"issue":"08","key":"ref7","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/j.clinph.2006.11.312","article-title":"Nonconvulsive seizures: developing a rational approach to the diagnosis and management in the critically ill population","volume":"118","author":"J Jirsch","year":"2007","journal-title":"Clin Neurophysiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"595","DOI":"10.3389\/fneur.2018.00595","article-title":"Practical management of epileptic seizures and status epilepticus in adult palliative care patients","volume":"9","author":"W Gr\u00f6nheit","year":"2018","journal-title":"Front Neurol"},{"issue":"04","key":"ref9","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1136\/practneurol-2017-001796","article-title":"Non-convulsive status epilepticus: mimics and chameleons","volume":"18","author":"M O Kinney","year":"2018","journal-title":"Pract Neurol"},{"key":"ref10","volume-title":"Pseudoseizures. 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