{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T23:06:08Z","timestamp":1745276768649,"version":"3.37.3"},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"02","funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Despite the increasing demand for complementary and integrative medicine, only a few studies have evaluated the effect of these types of treatments on the quality of life (QoL) of patients with chronic diseases. The objective of this study was to evaluate the QoL of women treated with homeopathy within the Public Health System of Belo Horizonte, Brazil.<\/jats:p><jats:p>\n          Methods\u2003This is a prospective randomized controlled pragmatic trial. The patients were divided into two independent groups, one group underwent homeopathic treatment in the first 6-month period and the other did not receive any homeopathic treatment. In both randomized groups, patients maintained their conventional medical treatment when necessary. The World Health Organization Quality of Life abbreviated questionnaire (WHOQOL-BREF) was used for QoL analysis prior to treatment and 6 months later.<\/jats:p><jats:p>\n          Results\u2003Randomization afforded similar baseline results in three domains of QoL analysis for both groups. After 6 months' treatment, there was a statistically significant difference between groups in the physical domain of WHOQOL-BREF: the average score improved to 63.6\u2009\u00b1\u2009(SD) 15.8 in the homeopathy group, compared with 53.1\u2009\u00b1\u2009(SD) 16.7 in the control group.<\/jats:p><jats:p>\n          Conclusions\u2003Homeopathic treatment showed a positive impact at 6 months on the QoL of women with chronic diseases. Further studies should be performed to determine the long-term effects of homeopathic treatment on QoL and its determinant factors.<\/jats:p>","DOI":"10.1055\/s-0040-1721062","type":"journal-article","created":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T23:45:42Z","timestamp":1614901542000},"page":"102-107","source":"Crossref","is-referenced-by-count":2,"title":["Impact of Homeopathic Treatment on the Quality of Life of Women with Chronic Diseases: A Randomized Controlled Pragmatic Trial"],"prefix":"10.1055","volume":"110","author":[{"given":"Nat\u00e1lia S.","family":"Champs","sequence":"additional","affiliation":[{"name":"PRHOAMA, Programa de Homeopatia, Acupuntura e Medicina Antropos\u00f3fica, Belo Horizonte Municipal Government, Belo Horizonte, Minas Gerais, Brazil"},{"name":"Complementary Therapies Research Group, Directory of Research Groups of the Scientific and Technological Development National Council (CNPq), Minas Gerais, Brazil"},{"name":"Department of Gynecology and Obstetrics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia G.","family":"Lopes","sequence":"additional","affiliation":[{"name":"Complementary Therapies Research Group, Directory of Research Groups of the Scientific and Technological Development National Council (CNPq), Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula C.","family":"Sousa","sequence":"additional","affiliation":[{"name":"Complementary Therapies Research Group, Directory of Research Groups of the Scientific and Technological Development National Council (CNPq), Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clariana C.","family":"Souza","sequence":"additional","affiliation":[{"name":"Complementary Therapies Research Group, Directory of Research Groups of the Scientific and Technological Development National Council (CNPq), Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara L.T.","family":"Justo","sequence":"additional","affiliation":[{"name":"Complementary Therapies Research Group, Directory of Research Groups of the Scientific and Technological Development National Council (CNPq), Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dayane M.","family":"Dutra","sequence":"additional","affiliation":[{"name":"Complementary Therapies Research Group, Directory of Research Groups of the Scientific and Technological Development National Council (CNPq), Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrienne M.S.","family":"Mendes","sequence":"additional","affiliation":[{"name":"PRHOAMA, Programa de Homeopatia, Acupuntura e Medicina Antropos\u00f3fica, Belo Horizonte Municipal Government, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6839-9308","authenticated-orcid":false,"given":"Claudia Prass","family":"Santos","sequence":"additional","affiliation":[{"name":"PRHOAMA, Programa de Homeopatia, Acupuntura e Medicina Antropos\u00f3fica, Belo Horizonte Municipal Government, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1886-1621","authenticated-orcid":false,"given":"Rubens L.C.","family":"Tavares","sequence":"additional","affiliation":[{"name":"Complementary Therapies Research Group, Directory of Research Groups of the Scientific and Technological Development National Council (CNPq), Minas Gerais, Brazil"},{"name":"Department of Gynecology and Obstetrics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,3,4]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e124","DOI":"10.1371\/journal.pmed.0020124","article-title":"Why most published research findings are false","volume":"2","author":"J P Ioannidis","year":"2005","journal-title":"PLoS Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1177\/1740774515598334","article-title":"Exploring the ethical and regulatory issues in pragmatic clinical trials","volume":"12","author":"R M Califf","year":"2015","journal-title":"Clin Trials"},{"key":"ref3","first-page":"1","article-title":"Trends in the use of complementary health approaches among adults: United States, 2002-2012","author":"T C Clarke","year":"2015","journal-title":"Natl Health Stat Rep"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1055\/s-0038-1636839","article-title":"Integration of homeopathy and complementary medicine in the Tuscan Public Health System and the experience of the Homeopathic Clinic of the Lucca Hospital","volume":"107","author":"E Rossi","year":"2018","journal-title":"Homeopathy"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ejogrb.2017.01.052","article-title":"Potentized estrogen in homeopathic treatment of endometriosis-associated pelvic pain: a 24-week, randomized, double-blind, placebo-controlled study","volume":"211","author":"M Z Teixeira","year":"2017","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1017\/S0033291798006667","article-title":"Development of the World Health Organization WHOQOL-BREF quality of life assessment","volume":"28","author":"The WHOQOL Group","year":"1998","journal-title":"Psychol Med"},{"key":"ref7","first-page":"178","article-title":"[Application of the Portuguese version of the abbreviated instrument of quality life WHOQOL-BREF]","volume":"34","author":"M P Fleck","year":"2000","journal-title":"Rev Saude Publica"},{"key":"ref8","first-page":"1475","article-title":"An open label pilot study testing the role of classical homeopathy in chronic allergic rhinitis","volume":"4","author":"S Ghosh","year":"2013","journal-title":"Int J Pharm Sci Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S1475-4916(03)00035-3","article-title":"The homeopathic approach to the treatment of symptoms of oestrogen withdrawal in breast cancer patients. 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