{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T20:17:26Z","timestamp":1778789846742,"version":"3.51.4"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Knee Surg"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this study was to determine patient-reported outcomes, hardware removal rates, as well as conversion to arthroplasty at mid-term follow-up following high tibial osteotomy (HTO) with a modern polyetheretherketone (PEEK) system. All PEEK system-based HTOs performed at a single institution between January 2010 and January 2016 with a minimum of 2 years follow-up were reviewed. Rates of postoperative complications, hardware removal and conversion to arthroplasty were calculated. Patient-reported outcomes including visual analog pain scale (VAS), Tegner activity scale, Lysholm, Knee Injury and Osteoarthritis Outcome Score (KOOS), and 36-Item Short Form Survey (SF-36) were obtained. Forty-seven HTOs in 43 patients (mean age: 37.6\u2009\u00b1\u200910.8 years; 30\u2009M, 13 F) were followed for a mean of 6.0\u2009\u00b1\u20091.5 years. A total of four postoperative complications occurred in three patients, resulting in an overall complication rate of 6.4%. Hardware removal occurred in three patients at a mean of 0.73\u2009\u00b1\u20090.53 years after surgery, with overall survival free of hardware removal of 96% (95% confidence interval [CI]: 85\u201399) at 1 year, 94% (95% CI: 82\u201398) at 2 years, and 94% (95% CI: 82\u201398) at 8 years. Conversion to arthroplasty occurred in three patients at a mean of 3.2\u2009\u00b1\u20091.0 years after surgery, with mean survival of 100% (95% CI: 94\u2013100) at 1 year, 100% (95% CI: 94\u2013100) at 2 years, and 93% (95% CI: 81\u201398) at 8 years. VAS at rest improved, from 3.1\u2009\u00b1\u20092.5 preoperatively to 1.1\u2009\u00b1\u20091.6 postoperatively (p\u2009&lt;\u20090.001). Patients remained active, with a mean Tegner activity scale of 4.4\u2009\u00b1\u20091.4 at final follow-up and satisfactory Lysholm, KOOS, and SF-36 scores. At mid-term follow-up, medial opening-wedge HTO using a modern PEEK-based system was found to be safe, efficacious, and durable, with satisfactory outcome scores and a low rate of conversion to arthroplasty. PEEK-based implants were found to have low hardware removal rates of 6% at 5 years, which compares favorably to historic metal fixation. This is a Level III study.<\/jats:p>","DOI":"10.1055\/s-0040-1721090","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T13:52:58Z","timestamp":1606225978000},"page":"916-921","source":"Crossref","is-referenced-by-count":8,"title":["High Tibial Osteotomy with a Modern Polyetheretherketone (PEEK) System: Mid-Term Results at a Mean of 6 Years Follow-Up"],"prefix":"10.1055","volume":"35","author":[{"given":"Lucas K.","family":"Keyt","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Hevesi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce A.","family":"Levy","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron J.","family":"Krych","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Camp","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2281-0018","authenticated-orcid":false,"given":"Michael J.","family":"Stuart","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"issue":"10","key":"ref1","doi-asserted-by":"crossref","first-page":"590","DOI":"10.5435\/00124635-201110000-00003","article-title":"The role of high tibial osteotomy in the varus knee","volume":"19","author":"R Rossi","year":"2011","journal-title":"J Am Acad Orthop Surg"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"279","DOI":"10.5435\/00124635-200507000-00007","article-title":"High tibial osteotomy","volume":"13","author":"J M Wright","year":"2005","journal-title":"J Am Acad Orthop Surg"},{"issue":"02","key":"ref3","doi-asserted-by":"crossref","first-page":"98","DOI":"10.11138\/jts\/2016.4.2.098","article-title":"High tibial osteotomy in varus knees: indications and limits","volume":"4","author":"M C Loia","year":"2016","journal-title":"Joints"},{"issue":"04","key":"ref4","first-page":"335","article-title":"[Long term results of 260 tibial osteotomies for frontal deviations of the knee]","volume":"58","author":"J Debeyre","year":"1972","journal-title":"Rev Chir Orthop Repar Appar Mot"},{"key":"ref5","first-page":"722","article-title":"[Value of corrective osteotomies in the treatment of certain knee diseases with axial deviation]","volume":"29","author":"J Debeyre","year":"1962","journal-title":"Rev Rhum Mal Osteoartic"},{"issue":"10","key":"ref6","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1007\/s00167-006-0074-1","article-title":"High tibial osteotomy with Puddu plate for the treatment of varus gonarthrosis","volume":"14","author":"M Asik","year":"2006","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"02","key":"ref7","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s00264-009-0861-7","article-title":"Correction accuracy and collateral laxity in open versus closed wedge high tibial osteotomy. 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