{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T03:31:19Z","timestamp":1784259079962,"version":"3.55.0"},"reference-count":14,"publisher":"Scientific Scholar","issue":"03","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Lab Physicians"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Infection is an important complication of childhood nephrotic syndrome (NS) and spontaneous bacterial peritonitis (SBP) is a frequently encountered one. We present a 7-year-old boy with NS who had decreased urine output, generalized body swelling, and abdominal pain. Urine analysis showed proteinuria of 50 mg\/m2\/d. Ascitic tap showed total leukocyte count of 100 cells\/mm3, sugar of 67 mg\/dL, and protein of 1.1 g\/dL. Gram stain revealed gram-negative bacilli with pus cells and culture grown Leclercia adecarboxylata (LAD). LAD was identified using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) with an identification score of 2.0. The organism showed good susceptibility to common antibiotics. The boy had no direct contact with livestock and the source of infection remains speculative. Devitalized skin because of massive edema seems to be the most plausible site of entry for the organism. Our patient was started on ceftriaxone and improved. LAD is a rare opportunistic pathogen, which belongs to Enterobacteriaceae and usually causes soft tissue infections. As far as we know, this is the first case where it has caused peritonitis in a child with NS. We also reviewed other pediatric cases.<\/jats:p>","DOI":"10.1055\/s-0040-1721162","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T13:27:49Z","timestamp":1606224469000},"page":"222-224","source":"Crossref","is-referenced-by-count":8,"title":["Leclercia adecarboxylata Causing Spontaneous Bacterial Peritonitis in a Child with Nephrotic Syndrome: A Case Report and Review of Literature"],"prefix":"10.25259","volume":"12","author":[{"given":"Ijas","family":"Hassan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Nephrology, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parakriti","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Research Block-A, Post Graduate Institute of Medical Education and Research, Chandigarh, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallab","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Research Block-A, Post Graduate Institute of Medical Education and Research, Chandigarh, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0918-3056","authenticated-orcid":false,"given":"Karalanglin","family":"Tiewsoh","sequence":"additional","affiliation":[{"name":"Division of Pediatric Nephrology, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s13312-013-0214-x","article-title":"Clinical spectrum and predictive risk factors of major infections in hospitalized children with nephrotic syndrome","volume":"50","author":"P Ajayan","year":"2013","journal-title":"Indian Pediatr"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.pcl.2018.08.006","article-title":"Nephrotic syndrome","volume":"66","author":"C S Wang","year":"2019","journal-title":"Pediatr Clin North Am"},{"key":"ref3","first-page":"726","article-title":"Biochemical study of pigmented Enterobacteriaceae [in French]","volume":"102","author":"H Leclerc","year":"1962","journal-title":"Ann Inst Pasteur (Paris)"},{"issue":"08","key":"ref4","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/j.1469-0691.2004.00892.x","article-title":"Natural antimicrobial susceptibility patterns and biochemical profiles of Leclercia adecarboxylata strains","volume":"10","author":"I Stock","year":"2004","journal-title":"Clin Microbiol Infect"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s10482-009-9396-6","article-title":"Bacteria colonizing root nodules of wild legumes exhibit virulence-associated properties of mammalian pathogens","volume":"97","author":"R Muresu","year":"2010","journal-title":"Antonie van Leeuwenhoek"},{"issue":"12","key":"ref6","first-page":"DD03","article-title":"Leclercia adecarboxylata isolation: case reports and review","volume":"8","author":"M Anuradha","year":"2014","journal-title":"J Clin Diagn Res"},{"issue":"09","key":"ref7","first-page":"41","article-title":"Leclercia adecarboxylata infection in an immunocompetent child","volume":"98","author":"E H Hurley","year":"2015","journal-title":"R I Med J (2013)"},{"key":"ref8","first-page":"160473","article-title":"Leclercia adecarboxylatamusculoskeletal infection in an immune competent pediatric patient: an emerging pathogen?","volume":"2015","author":"W J Grantham","year":"2015","journal-title":"Case Rep Orthop"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/jpids\/pis131","article-title":"Leclercia adecarboxylata sepsis and cerebral herniation","volume":"3","author":"K Sethi","year":"2014","journal-title":"J Pediatric Infect Dis Soc"},{"issue":"09","key":"ref10","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1038\/jp.2013.34","article-title":"Late-onset Leclercia adecarboxylata sepsis in a premature neonate","volume":"33","author":"M U Nelson","year":"2013","journal-title":"J Perinatol"},{"issue":"01","key":"ref11","doi-asserted-by":"crossref","first-page":"e37","DOI":"10.1111\/j.1651-2227.2011.02431.x","article-title":"Late-onset Leclercia adecarboxylata bacteraemia in a premature infant in the NICU","volume":"101","author":"K A Myers","year":"2012","journal-title":"Acta Paediatr"},{"issue":"20","key":"ref12","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0196-4399(91)90067-6","article-title":"Leclercia adecarboxylata isolated from a blood culture","volume":"13","author":"E Otani","year":"2015","journal-title":"Clin Microbiol Newsl"},{"issue":"11","key":"ref13","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1086\/320539","article-title":"Isolation of Leclercia adecarboxylata from an infant with acute lymphoblastic leukemia","volume":"32","author":"C A Longhurst","year":"2001","journal-title":"Clin Infect Dis"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s004670000436","article-title":"Leclercia adecarboxylata peritonitis in a child receiving chronic peritoneal dialysis","volume":"15","author":"O Fattal","year":"2000","journal-title":"Pediatr Nephrol"}],"container-title":["Journal of Laboratory Physicians"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1721162.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T08:16:52Z","timestamp":1703405812000},"score":1,"resource":{"primary":{"URL":"https:\/\/jlabphy.org\/leclercia-adecarboxylata-causing-spontaneous-bacterial-peritonitis-in-a-child-with-nephrotic-syndrome-a-case-report-and-review-of-literature\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,23]]},"references-count":14,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2020,11,23]]},"published-print":{"date-parts":[[2020,12]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1721162","relation":{},"ISSN":["0974-2727","0974-7826"],"issn-type":[{"value":"0974-2727","type":"print"},{"value":"0974-7826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,23]]}}}