{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T12:02:28Z","timestamp":1648641748016},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T00:00:00Z","timestamp":1614729600000},"content-version":"vor","delay-in-days":61,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European J Pediatr Surg Rep"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>With the advances of neonatology, the survival rate for \u201clive-born periviable fetuses\u201d weighing\u2009&lt;\u2009300\u2009g, a subgroup of extremely low birth weight (BW) infants, has improved over the past 10 years. Meconium-related ileus (MRI) represents an early postnatal hazard, and, if medical evacuation fails, a surgical challenge in such immature babies. We report the interdisciplinary management of surgically treated MRI in a newborn with a BW of 273\u2009g. According to the worldwide database held by the University of Iowa, he is registered as the tiniest male newborn in Europe. The boy was born in the 25th gestational week by cesarean section after a triplet pregnancy with twin\u2013twin transfusion syndrome, him being the donor. He had a BW of 273\u2009g, whereas his brothers had a BW of 740\u2009g and 722\u2009g. Cardiopulmonary stabilization and ventilation were successful. He developed MRI unresponsive to medical treatment. On day 14 of life, a minilaparotomy was performed in the right lower quadrant to externalize a loop of the distal ileum in a no-touch technique. Despite the small diameter of only 2\u2009mm, a standard loop ileostomy could be fashioned. There were no intra- or postoperative abdominal complications. Bowel function and weight gain were adequate and the ileostomy was closed electively 5 months later at a body weight of 3.5\u2009kg.<\/jats:p><jats:p>In summary, minilaparotomy and loop ileostomy placement were effective to treat surgical MRI in Europe's tiniest male newborn. With the advances of neonatology, pediatric surgery reaches new frontiers as well.<\/jats:p>","DOI":"10.1055\/s-0040-1721406","type":"journal-article","created":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T00:14:27Z","timestamp":1614816867000},"page":"e17-e19","source":"Crossref","is-referenced-by-count":0,"title":["Loop Ileostomy in Europe's Tiniest Male Newborn for Meconium-Related Ileus"],"prefix":"10.1055","volume":"09","author":[{"given":"Holger","family":"Till","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Singer","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Castellani","sequence":"additional","affiliation":[{"name":"Department of Paediatric and Adolescent Surgery, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berndt","family":"Urlesberger","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine, Division of Neonatology, Medical University of Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,3,3]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1055\/s-2008-1072290","article-title":"Functional ileus in neonates: Hirschsprung's disease-allied disorders versus meconium-related ileus","volume":"9","author":"A Kubota","year":"1999","journal-title":"Eur J Pediatr Surg"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"4674","DOI":"10.1038\/s41598-020-60016-3","article-title":"Risk factors of meconium-related ileus in very low birth weight infants: patients-control study","volume":"10","author":"J Byun","year":"2020","journal-title":"Sci Rep"},{"issue":"03","key":"ref3","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1442-200X.2010.03231.x","article-title":"Therapeutic strategies of meconium obstruction of the small bowel in very-low-birthweight neonates","volume":"53","author":"T Koshinaga","year":"2011","journal-title":"Pediatr Int"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1824-7288-37-55","article-title":"Meconium obstruction in absence of cystic fibrosis in low birth weight infants: an emerging challenge from increasing survival","volume":"37","author":"V F Paradiso","year":"2011","journal-title":"Ital J Pediatr"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.jpedsurg.2012.02.019","article-title":"A review of pathophysiology and management of fetuses and neonates with meconium ileus for the pediatric surgeon","volume":"47","author":"B E Carlyle","year":"2012","journal-title":"J Pediatr Surg"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4174\/astr.2015.89.3.151","article-title":"Meconium-related ileus in very low birth weight and extremely low birth weight infants: immediate and one-year postoperative outcomes","volume":"89","author":"H Y Kim","year":"2015","journal-title":"Ann Surg Treat Res"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jpeds.2017.05.017","article-title":"Early mortality and morbidity in infants with birth weight of 500\u2009grams or less in Japan","volume":"190","author":"H Inoue","year":"2017","journal-title":"J Pediatr"},{"issue":"01","key":"ref8","first-page":"146","article-title":"Continually improving outcomes for very low birth weight infants","volume":"146","author":"R F Soll","year":"2020","journal-title":"Pediatrics"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"4474","DOI":"10.12659\/MSM.907652","article-title":"Trends in mortality and morbidity in infants under 500 grams birthweight: observations from our neonatal intensive care unit (NICU)","volume":"24","author":"P Varga","year":"2018","journal-title":"Med Sci Monit"},{"issue":"02","key":"ref10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/00000658-199202000-00014","article-title":"Management and survival of meconium ileus. 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