{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:07:32Z","timestamp":1788480452356,"version":"build-2803163510"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003Treatment of destructive endocarditis with abscess formation is a surgical challenge and associated with significant morbidity and mortality. A root replacement is often performed in case of an annular abscess. This retrospective study was designed to assess the long-term outcome of extensive debridement and patch reconstruction as an alternative approach.<\/jats:p><jats:p>\n          Methods\u2003Between November 2007 and November 2016, a selected group of 79 patients (29.6% of all surgical endocarditis cases) with native valve endocarditis (NVE, 53.2%) or prosthetic valve endocarditis (PVE, 46.8%) valve endocarditis underwent surgical therapy with extensive annular debridement and patch reconstruction. Their postoperative course, freedom from recurrent endocarditis, and survival at 1, 5, and 7 years were evaluated.<\/jats:p><jats:p>\n          Results\u2003About two-thirds of patients were in a stable condition, one-third of patients were in a critical state. The median logistic EuroSCORE I was 17%. Infected tissue was removed, and defect closure was performed, either with autologous pericardium for small defects, or with bovine pericardium for larger defects. Overall, in-hospital mortality was 11.3% (NVE: 9.7%, PVE: 13.2%; p\u2009=\u20090.412). In single valve endocarditis survival at 1, 5, and 7 years was 81, 72, 72%, respectively for NVE, and 80, 57, 57%, respectively for PVE (p\u2009=\u20090.589), whereas in multiple valve endocarditis survival at 1, 5, and 7 years was 82, 82, 82% for NVE, and 61, 61, and 31%, respectively for PVE (p\u2009=\u20090.132). Confirmed late reinfection was very low.<\/jats:p><jats:p>\n          Conclusion\u2003Surgical treatment of destructive endocarditis with abscess formation using patch repair techniques offers acceptable early and long-term results. The relapse rate was low. PVE and involvement of multiple valves were associated with worse outcomes.<\/jats:p>","DOI":"10.1055\/s-0040-1721462","type":"journal-article","created":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:59:31Z","timestamp":1609462771000},"page":"22-28","source":"Crossref","is-referenced-by-count":3,"title":["Long-Term Results of Patch Repair in Destructive Valve Endocarditis"],"prefix":"10.1055","volume":"71","author":[{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Zilz","sequence":"additional","affiliation":[{"name":"Department of Occupational, Social and Environmental Medicine, Ludwig-Maximilian University Hospital Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Floerchinger","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Holzamer","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Camboni","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Schach","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II\u2014Cardiology, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"Schmid","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1188-6460","authenticated-orcid":false,"given":"Leopold","family":"Rupprecht","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,12,31]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.athoracsur.2006.09.023","article-title":"Mitral valve repair and replacement in endocarditis: a systematic review of literature","volume":"83","author":"H HH Feringa","year":"2007","journal-title":"Ann Thorac Surg"},{"key":"ref2","first-page":"517","volume-title":"Robbins' Pathologic Basis of Disease","author":"R S Cotran","year":"1994","edition":"5th ed."},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1161\/01.CIR.54.1.140","article-title":"Valve ring abscess in active infective endocarditis. 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