{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T06:36:06Z","timestamp":1771655766880,"version":"3.50.1"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003This study was aimed to illustrate the features and complexities of nonspecific orbital inflammation via discussion of two representative cases.<\/jats:p><jats:p>\n          Design\u2003Present study is a retrospective case review.<\/jats:p><jats:p>\n          Setting\u2003The study was conducted at a tertiary care medical center.<\/jats:p><jats:p>\n          Participants\u2003Two patients with nonspecific orbital inflammation were participants of this retrospective study.<\/jats:p><jats:p>\n          Main Outcome Measures\u2003Outcome of the study was disease-free patients and off all medications.<\/jats:p><jats:p>\n          Results\u2003At follow-up, both patients are disease free and off all medications.<\/jats:p><jats:p>\n          Conclusion\u2003Surgery plays a diagnostic and therapeutic role. While the clinical subtype is important for differential diagnosis and symptomatic treatment, the histologic subtype is similarly important. For inflammatory dacryoadenitis, surgery can be therapeutic. For extensive granulomatosis with polyangiitis, debulking surgery may allow better penetration of medications, especially rituximab.<\/jats:p>","DOI":"10.1055\/s-0040-1722636","type":"journal-article","created":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:20:22Z","timestamp":1612311622000},"page":"096-099","source":"Crossref","is-referenced-by-count":11,"title":["Not a Tumor-Nonspecific Orbital Inflammation"],"prefix":"10.1055","volume":"82","author":[{"given":"James A.","family":"Garrity","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,2,2]]},"reference":[{"key":"ref1","volume-title":"Handbuch der Gesamten Augenheilkunden: Die Krankheiten der Orbita","author":"A Birch-Hirschfeld","year":"1930","edition":"2nd ed."},{"key":"ref2","first-page":"2777","volume-title":"Orbit","author":"F A Jakobiec","year":"1986"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"957","DOI":"10.2214\/ajr.137.5.957","article-title":"Acute orbital pseudotumors: classification and CT features","volume":"137","author":"R A Nugent","year":"1981","journal-title":"AJR Am J Roentgenol"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0039-6257(84)90166-8","article-title":"The nonspecific orbital inflammatory syndromes","volume":"29","author":"J S Kennerdell","year":"1984","journal-title":"Surv Ophthalmol"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.ajo.2004.04.026","article-title":"Inflammatory orbital pseudotumor with extension beyond the orbit","volume":"138","author":"M A Mahr","year":"2004","journal-title":"Am J Ophthalmol"},{"issue":"05","key":"ref6","first-page":"581","article-title":"Idiopathic sclerosing inflammation of the orbit: immunohistologic analysis and comparison with retroperitoneal fibrosis","volume":"6","author":"J M McCarthy","year":"1993","journal-title":"Mod Pathol"},{"issue":"03","key":"ref7","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S0161-6420(94)31298-X","article-title":"Idiopathic sclerosing inflammation of the orbit. 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