{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:38:49Z","timestamp":1740166729899,"version":"3.37.3"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003Antibiotic use in lateral skull base surgery (LSBS) has not been thoroughly investigated in the literature. There is wide variability in antibiotic use and insufficient data to guide management. This study aims to describe the factors and patterns influencing antibiotic use in LSBS among the membership of the North American Skull Base Society (NASBS).<\/jats:p><jats:p>\n          Design\u2003An online-based survey was designed and distributed to the membership of the NASBS. Data was analyzed using bivariate analysis and logistic regression modeling.<\/jats:p><jats:p>\n          Setting\u2003Online-based questionnaire.<\/jats:p><jats:p>\n          Participants\u2003NASBS membership.<\/jats:p><jats:p>\n          Main Outcome Measures\u2003Use of intraoperative antibiotics and use of postoperative antibiotics.<\/jats:p><jats:p>\n          Results\u2003The survey response rate was 26% (208 respondents). Of the 208 total respondents, 143 (69%) respondents performed LSBS. Most respondents are neurosurgeons (69%) with the remaining being otolaryngologists (31%). The majority of respondents (79%) are fellowship-trained in skull base surgery. Academic or government physicians make up 69% of respondents and 31% are in private practice with or without academic affiliations. Bivariate analysis showed that practice setting significantly influenced intraoperative antibiotic use (p\u2009=\u20090.01). Geographic location significantly affected postoperative antibiotic use (p\u2009=\u20090.01). Postoperative antibiotic duration was significantly affected by presence of chronic otitis media, cerebrospinal fluid leak, and surgeon training (p\u2009=\u20090.02, p\u2009=\u20090.01, and p\u2009=\u20090.006, respectively). Logistic regression modeling showed that the motivation to reduce infection significantly impacted postoperative antibiotic use (p\u2009=\u20090.03).<\/jats:p><jats:p>\n          Conclusion\u2003This study demonstrates significant variations in intraoperative and postoperative antibiotic use in LSBS among the NASBS membership. Appropriate guidelines for optimal perioperative antibiotic use patterns should be determined with randomized studies in the future.<\/jats:p>","DOI":"10.1055\/s-0040-1722642","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T01:14:53Z","timestamp":1612487693000},"page":"237-247","source":"Crossref","is-referenced-by-count":0,"title":["Antibiotic Use in Lateral Skull Base Surgery: A Survey of the North American Skull Base Society"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9592-078X","authenticated-orcid":false,"given":"Kevin L.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina H.","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian S.","family":"Hawn","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijay","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Albert Einstein College of Medicine, Bronx, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varun R.","family":"Kshettry","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Bellile","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadeem A.","family":"Akbar","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, New York, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin L.","family":"McKean","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waleed M.","family":"Abuzeid","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery, University of Washington, Seattle, Washington, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard S.","family":"Moskowitz","sequence":"additional","affiliation":[{"name":"Department of 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