{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T03:18:42Z","timestamp":1752981522293,"version":"3.37.3"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Mitral valve (MV) repair with annuloplasty is the standard of care in patients with primary degenerative mitral regurgitation (DMR). Newer generations of annuloplasty rings have been developed with the goals of closer reproduction of native annular geometry and easier implantation. This study investigates the short-term and 5-year clinical outcomes of MV repair with the Carpentier-Edwards (CE) Physio II annuloplasty ring.<\/jats:p><jats:p>\n          Methods\u2003This is an observational study including a total of 486 patients who underwent MV repair for DMR using the CE Physio II annuloplasty ring between 2011 and 2016.<\/jats:p><jats:p>\n          Results\u2003Mean age was 54.8\u2009\u00b1\u200912.1 years, 364 patients (74.9%) were males, and 84 patients (17.3%) presented with atrial fibrillation. Mean left ventricular ejection fraction was 62.3\u2009\u00b1\u20097.3%. Mean logistic EuroSCORE was 2.7\u2009\u00b1\u20092.4%. New York Heart Association functional class III\u2013IV symptoms were present in 134 (27.6%) patients preoperatively. Isolated MV repair was performed via a right-sided mini-thoracotomy in 479 patients (98.6%). Concomitant procedures included ablation for atrial fibrillation in 83 patients (17.1%) and closure of atrial septum defect in 88 patients (18.1%). Median size of implanted annuloplasty rings was 34\u2009mm (interquartile range: 34\u201338\u2009mm). Mean cardiopulmonary bypass time was 116\u2009\u00b1\u200934\u2009minutes and mean cross-clamp time was 74\u2009\u00b1\u200925\u2009minutes. Thirty-day mortality was 0.4%. The Kaplan\u2013Meier 4-year survival was 98.5%. Freedom from MV reoperation was 96.2 and 94.0% at 1 and 4 years.<\/jats:p><jats:p>\n          Conclusion\u2003MV repair with the CE Physio II annuloplasty ring is associated with excellent midterm clinical outcome.<\/jats:p>","DOI":"10.1055\/s-0040-1722651","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T00:18:13Z","timestamp":1613693893000},"page":"100-105","source":"Crossref","is-referenced-by-count":5,"title":["Clinical Outcomes after Mitral Valve Repair with the Physio II Annuloplasty Ring"],"prefix":"10.1055","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0245-0147","authenticated-orcid":false,"given":"Thilo","family":"Noack","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz","family":"Sieg","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mateo Marin","family":"Cuartas","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Spampinato","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Holzhey","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joerg","family":"Seeburger","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael Andrew","family":"Borger","sequence":"additional","affiliation":[{"name":"University Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,2,18]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.jcmg.2018.01.009","article-title":"Mitral valve regurgitation in the contemporary era: insights into diagnosis, management, and future directions","volume":"11","author":"A El Sabbagh","year":"2018","journal-title":"JACC Cardiovasc Imaging"},{"issue":"22","key":"ref2","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1016\/j.jacc.2014.02.577","article-title":"Early surgery versus conventional treatment for asymptomatic severe mitral regurgitation: a propensity analysis","volume":"63","author":"D H 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