{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:52:36Z","timestamp":1792785156769,"version":"4.5.0"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T00:00:00Z","timestamp":1615420800000},"content-version":"vor","delay-in-days":69,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"name":"University of Erlangen Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg Rep"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background\u2003Marfan's syndrome (MFS) is a connective tissue disorder, caused by a mutation in the FBN-1 gene and affecting multiple organ systems including the vascular system. During pregnancy, women with MFS have an increased risk of aortic dissection due to changes in the cardiovascular system.<\/jats:p>\n                  <jats:p>Case Description\u2003We present a 39-year-old woman that suffered from an acute aortic dissection in week 33 of her third pregnancy who urgently required lifesaving surgery. Three-dimensional reconstruction of computed tomography scan was performed with unborn child in utero.<\/jats:p>\n                  <jats:p>Conclusion\u2003Monitoring of patients with suspected or confirmed MFS appears essential and interdisciplinary treatment and prevention strategies are required.<\/jats:p>","DOI":"10.1055\/s-0040-1722705","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T19:14:21Z","timestamp":1615490061000},"page":"e18-e21","source":"Crossref","is-referenced-by-count":4,"title":["Acute Type A Dissection during Pregnancy with Marfan's Syndrome"],"prefix":"10.1055","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5884-5856","authenticated-orcid":false,"given":"Christian","family":"Heim","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp P.","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Weyand","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Harig","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,3,11]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.gene.2016.07.033","article-title":"FBN1: the disease-causing gene for Marfan syndrome and other genetic disorders","volume":"591","author":"L Y Sakai","year":"2016","journal-title":"Gene"},{"issue":"09","key":"ref2","doi-asserted-by":"crossref","first-page":"603","DOI":"10.5435\/JAAOS-D-16-00143","article-title":"Marfan syndrome: a clinical update","volume":"25","author":"A D Bitterman","year":"2017","journal-title":"J Am Acad Orthop Surg"},{"issue":"22","key":"ref3","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1136\/heartjnl-2016-310631","article-title":"Relationship between fibrillin-1 genotype and severity of cardiovascular involvement in Marfan syndrome","volume":"103","author":"R Franken","year":"2017","journal-title":"Heart"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s00392-016-1028-3","article-title":"Aortic events in a nationwide Marfan syndrome cohort","volume":"106","author":"K A Groth","year":"2017","journal-title":"Clin Res 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