{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:52:37Z","timestamp":1792785157314,"version":"4.5.0"},"reference-count":29,"publisher":"Georg Thieme Verlag KG","issue":"09","funder":[{"name":"Frederick Banting and Charles Best Canadian Graduate Scholarship\u2013Master's Award"},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background\u2003Venous thromboembolism (VTE) in pregnancy can have numerous adverse impacts on patients and health care systems. Ongoing research aimed at improving maternal and fetal\/neonatal outcomes is hampered by the lack of patient perspective in determining which outcomes are considered important to assess the effectiveness of interventions.<\/jats:p>\n                  <jats:p>Objectives\u2003The objective of this study was to elicit outcomes from those who experienced or were at risk for pregnancy-associated VTE (health service users, HSUs) and health care providers (HCPs) involved in their care.<\/jats:p>\n                  <jats:p>Methods\u2003Canadian HSUs and HCPs were recruited using convenience and purposive sampling, respectively. Individual, semistructured interviews aimed specifically at eliciting pregnancy-related outcomes were conducted until data saturation was attained. Interviews were audio-recorded and transcribed verbatim. Written transcripts were de-identified and interpretatively analyzed in duplicate to obtain outcomes related to participant experiences. Outcomes were grouped based on a taxonomy developed for medical research and compared between and across interviews with patients and HCPs, and with those obtained through a systematic review of the published literature.<\/jats:p>\n                  <jats:p>Results and Conclusion\u2003We interviewed 10 HSUs and eight HCPs and elicited 52 outcomes, 21 of which have not been reported in the literature. Although the majority of elicited outcomes were in the clinical\/physiological core outcome area, both HSUs and HCPs highlighted the importance of outcomes related to functioning\/life impact and general wellbeing of mother and baby. These outcomes representing the perspectives of HSUs and HCPs should be considered while conducting trials on pregnancy-associated VTE.<\/jats:p>","DOI":"10.1055\/s-0041-1722855","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T18:53:59Z","timestamp":1612983239000},"page":"1228-1236","source":"Crossref","is-referenced-by-count":6,"title":["Patient- and Health-Care-Provider-Reported Outcomes to Consider in Research on Pregnancy-Associated Venous Thromboembolism"],"prefix":"10.1055","volume":"121","author":[{"given":"Alexandria","family":"King","sequence":"additional","affiliation":[{"name":"Institute of Medical Science, University of Toronto, Canada"},{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haley","family":"Leider","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan","family":"Herman","sequence":"additional","affiliation":[{"name":"Institute of Medical Science, University of Toronto, Canada"},{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann Kinga","family":"Malinowski","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Toronto, Canada"},{"name":"Lunenfeld\u2013Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"D'Souza","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Toronto, Canada"},{"name":"Lunenfeld\u2013Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,2,10]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1161\/ATVBAHA.109.184127","article-title":"Venous thromboembolism in pregnancy","volume":"29","author":"A H James","year":"2009","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref2","volume-title":"Saving Lives, Improving Mothers' Care: lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2015\u201317","author":"M Knight","year":"2019"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"e275","DOI":"10.1016\/j.crvasa.2015.05.009","article-title":"2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. 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