{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:31:46Z","timestamp":1763141506890,"version":"3.37.3"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Mitral valved stents tend to migrate or to develop paravalvular leakage due to high\u2013left ventricular pressure in this cavity. Thus, this study describes a newly developed mitral valved stent anchoring technology.<\/jats:p><jats:p>\n          Methods\u2003Based on an existing mitral valved stent, four anchoring units with curved surgical needles were designed and fabricated using three-dimensional (3D) software and print technology. Mitral nitinol stents assembled with four anchoring units were successively fixed on 10 porcine annuli. Mechanical tests were performed with a tensile force test system and recorded the tension forces of the 10 nitinol stents on the annulus.<\/jats:p><jats:p>\n          Results\u2003The average maximum force was 28.3\u2009\u00b1\u20095.21\u2009N, the lowest was 21.7\u2009N, and the highest was 38.6\u2009N until the stent lost contact with the annulus; for the break force (zero movement of stent from annulus), the average value was 18.5\u2009\u00b1\u20096.7\u2009N with a maximum value of 26.9\u2009N and a minimum value of 6.07\u2009N. It was additionally observed that the puncture needles of the anchoring units passed into the mitral annulus in all 10 hearts and further penetrated the myocardium in only one additional heart. The anchoring units enhanced the tightness of the mitral valved stent and did not destroy the circumflex coronary artery, coronary sinus, right atrium, aortic root, or the left ventricular outflow tract.<\/jats:p><jats:p>\n          Conclusion\u2003The new anchoring units for mitral nitinol stents were produced with 3D software and printing technology; with this new type of anchoring technology, the mitral valved stent can be tightly fixed toward the mitral annulus.<\/jats:p>","DOI":"10.1055\/s-0041-1722976","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T01:06:43Z","timestamp":1612487203000},"page":"126-132","source":"Crossref","is-referenced-by-count":1,"title":["Transcatheter Mitral Valve Replacement: A Novel Anchor Technology"],"prefix":"10.1055","volume":"70","author":[{"given":"Yazhou","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Experimental Cardiac Surgery and Heart Valve Replacement, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"},{"name":"Department of Cardiothoracic Surgery, The First People's Hospital of Jingmen, Hubei Minzu University, Jingmen, Hubei, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Lutter","sequence":"additional","affiliation":[{"name":"Department of Experimental Cardiac Surgery and Heart Valve Replacement, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"},{"name":"Department of Cardiovascular Surgery, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Knueppel","sequence":"additional","affiliation":[{"name":"Department of Experimental Cardiac Surgery and Heart Valve Replacement, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"},{"name":"Department of Cardiovascular Surgery, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derk","family":"Frank","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucian","family":"Lozonschi","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Tampa University, Tampa, Florida, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rouven","family":"Berndt","sequence":"additional","affiliation":[{"name":"Department of Experimental Cardiac Surgery and Heart Valve Replacement, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"},{"name":"Department of Cardiovascular Surgery, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Attmann","sequence":"additional","affiliation":[{"name":"Department of Experimental Cardiac Surgery and Heart Valve Replacement, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"},{"name":"Department of Cardiovascular Surgery, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4990-1892","authenticated-orcid":false,"given":"Thomas","family":"Puehler","sequence":"additional","affiliation":[{"name":"Department of Experimental Cardiac Surgery and Heart Valve Replacement, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, Germany"},{"name":"Department of Cardiovascular Surgery, Christian-Albrechts-University of Kiel, School of Medicine, UKSH, Kiel, 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