{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T20:34:43Z","timestamp":1781901283712,"version":"3.54.5"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and Objective\u2003Trigeminal neuralgia is a common neurologic disease that seriously impacts a patient's quality of life. We retrospectively investigated the efficacy and safety of internal neurolysis (nerve combing) for trigeminal neuralgia without vascular compression.<\/jats:p><jats:p>\n          Patients and Methods\u2003This study was a retrospective review of all patients with trigeminal neuralgia who were admitted between January 2014 and February 2019. A subgroup of 36 patients had no vascular compression at surgery and underwent internal neurolysis. Chart review and postoperative follow-up were performed to assess the overall outcomes of internal neurolysis.<\/jats:p><jats:p>\n          Results\u2003Thirty-six patients were identified, with a mean age of 44.89\u2009\u00b1\u20097.90 (rang: 31\u201365) years and a disease duration of 5.19\u2009\u00b1\u20092.61 years. The immediate postoperative pain relief (Barrow Neurological Institute [BNI] pain score of I or II) rate was 100%. The medium- to long-term pain relief rate was 91.7%. Three patients experienced recurrence. Facial numbness was the primary postoperative complication. Four patients with a score of III on the BNI numbness scale immediately after surgery had marked improvement at 6 months. No serious complications occurred.<\/jats:p><jats:p>\n          Conclusion\u2003Internal neurolysis is a safe and effective treatment for trigeminal neuralgia without vascular compression or clear responsible vessels.<\/jats:p>","DOI":"10.1055\/s-0041-1723809","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T23:35:39Z","timestamp":1618270539000},"page":"364-368","source":"Crossref","is-referenced-by-count":14,"title":["Efficacy of Internal Neurolysis for Trigeminal Neuralgia without Vascular Compression"],"prefix":"10.1055","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1394-7845","authenticated-orcid":false,"given":"Ming-Wu","family":"Li","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Hospital, Anhui Provincial Stereotactic Neurological Institute, Anhui Provincial Key Laboratory of Brain Function and Disease \u2013 Neurosurgery, Anhui, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-feng","family":"Jiang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China Anhui provincial hospital \u2013 Neurosurgery, Anhui, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoshi","family":"Niu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medial University, Hefei, Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2021,4,12]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"585","DOI":"10.4103\/ajns.AJNS_67_14","article-title":"Trigeminal neuralgia","volume":"12","author":"Y R Yadav","year":"2017","journal-title":"Asian J Neurosurg"},{"issue":"14","key":"ref2","first-page":"73","article-title":"Percutaneous balloon compression for trigeminal neuralgia","volume":"56","author":"J A Brown","year":"2009","journal-title":"Clin Neurosurg"},{"key":"ref3","first-page":"ONS270","article-title":"The subtemporal interdural approach to dumbbell-shaped trigeminal schwannomas: cadaveric prosection","volume":"59","author":"S Youssef","year":"2006","journal-title":"Neurosurgery"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s101430050031","article-title":"Anatomical study of the lateral wall of the cavernous sinus, emphasizing dural construction and neural relations","volume":"23","author":"E Tuccar","year":"2000","journal-title":"Neurosurg Rev"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1097\/00002508-200201000-00002","article-title":"Pathophysiology of trigeminal neuralgia: the ignition hypothesis","volume":"18","author":"M Devor","year":"2002","journal-title":"Clin J Pain"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3171\/jns.1967.26.1part2.0159","article-title":"Arterial compression of the trigeminal nerve at the pons in patients with trigeminal neuralgia","volume":"26","author":"P J Jannetta","year":"1967","journal-title":"J Neurosurg"},{"issue":"01","key":"ref7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s701-002-8269-4","article-title":"Anatomical observations during microvascular decompression for idiopathic trigeminal neuralgia (with correlations between topography of pain and site of the neurovascular conflict). 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