{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:02Z","timestamp":1740126842492,"version":"3.37.3"},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The transcatheter valve-in-valve treatment (TAV-in-TAV) of degenerated transcatheter aortic valves is becoming more relevant, as the use of transcatheter aortic valve replacement (TAVR) increases. We report our experience with TAV-in-TAV in patients with a degenerated transcatheter heart valve (THV).<\/jats:p><jats:p>\n          Methods\u2003We retrospectively analyzed prospectively collected data from our designated TAVR database. Intraprocedural and intrahospital outcomes were reported.<\/jats:p><jats:p>\n          Results\u2003Ten patients out of a total of 3,144 TAVR implantations since 2007 presented with a degenerated THV, among those six with an Edwards Sapien XT (Edwards Lifesciences, Irvine, California, United States) valve, treated with a Medtronic Evolut R (Medtronic, Dublin, Ireland) valve. Four patients had severe stenosis, one pure insufficiency, and five combined stenosis and insufficiency. Average time between initial implantation and re-intervention was 6.8\u2009\u00b1\u20091.3 years. The mean preoperative maximum and mean gradients were 54.2\u2009\u00b1\u200914.8\u2009mm Hg and 31.6\u2009\u00b1\u20099.9\u2009mm Hg, respectively. Nine patients underwent transfemoral and one patient underwent transaortic TAV-in-TAV. Mean procedural time was 86.2\u2009\u00b1\u200951.5\u2009minutes. Post-implantation, the maximum and mean gradients decreased to 18\u2009\u00b1\u20096.9\u2009mm Hg and 8.4\u2009\u00b1\u20093.2\u2009mm Hg (16\u2009\u00b1\u20098\u2009mm Hg and 6.4\u2009\u00b1\u20091.7\u2009mm Hg in the Evolut-in-Sapien subgroup), respectively. The valve area increased from 0.98\u2009\u00b1\u20090.28\u2009mm Hg to 1.72\u2009\u00b1\u20090.32\u2009mm Hg (0.8\u2009\u00b1\u20090.07\u2009mm Hg to 1.9\u2009\u00b1\u20090.16\u2009mm Hg in the Evolut-in-Sapien subgroup). Two patients experienced a vascular complication. No further Valve Academic Research Consortium-2 criteria complications occurred during hospitalization.<\/jats:p><jats:p>\n          Conclusion\u2003TAV-in-TAV resulted in low procedural and peri-procedural complication rates. In particular, the usage of a supra-annular valve resulted in excellent hemodynamic results. Larger studies are required to validate this observational data and to establish a protocol for this procedure.<\/jats:p>","DOI":"10.1055\/s-0041-1724038","type":"journal-article","created":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T23:50:14Z","timestamp":1614210614000},"page":"213-216","source":"Crossref","is-referenced-by-count":0,"title":["Transcatheter Aortic Valve Replacement for a Degenerated Transcatheter Valve\u2014A Single Center Experience"],"prefix":"10.1055","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7560-9257","authenticated-orcid":false,"given":"Magdalena","family":"Erlebach","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, German Heart Centre, Munich, Germany"},{"name":"Department of Cardiovascular Surgery, INSURE (Institute of Translational Cardiac Surgery), German Heart Center Munich, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik","family":"Ruge","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, German Heart Centre, Munich, Germany"},{"name":"Department of Cardiovascular Surgery, INSURE (Institute of Translational Cardiac Surgery), German Heart Center Munich, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruediger","family":"Lange","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, German Heart Centre, Munich, Germany"},{"name":"Department of Cardiovascular Surgery, INSURE (Institute of Translational Cardiac Surgery), German Heart Center Munich, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,2,24]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1001\/jama.2014.7246","article-title":"Transcatheter aortic valve implantation in failed bioprosthetic surgical valves","volume":"312","author":"D Dvir","year":"2014","journal-title":"JAMA"},{"issue":"16","key":"ref2","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1016\/j.jacc.2020.02.051","article-title":"Repeat transcatheter aortic valve replacement for transcatheter prosthesis dysfunction","volume":"75","author":"U Landes","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"19","key":"ref3","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1161\/CIRCULATIONAHA.112.104505","article-title":"Transcatheter aortic valve replacement for degenerative bioprosthetic surgical valves: results from the global valve-in-valve registry","volume":"126","author":"D Dvir","year":"2012","journal-title":"Circulation"},{"issue":"25","key":"ref4","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1161\/CIRCULATIONAHA.113.000631","article-title":"Transcatheter aortic valve replacement for bioprosthetic aortic valve failure: the valve-in-valve procedure","volume":"127","author":"J G Webb","year":"2013","journal-title":"Circulation"},{"issue":"06","key":"ref5","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.jcin.2020.01.227","article-title":"Chimney stenting for coronary occlusion during TAVR: insights from the Chimney Registry","volume":"13","author":"F Mercanti","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"issue":"07","key":"ref6","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.jcin.2018.01.247","article-title":"Transcatheter laceration of aortic leaflets to prevent coronary obstruction during transcatheter aortic valve replacement: concept to first-in-human","volume":"11","author":"J M Khan","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"issue":"10","key":"ref7","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1136\/heartjnl-2017-312422","article-title":"Incidence, predictors and clinical outcomes of residual stenosis after aortic valve-in-valve","volume":"104","author":"S Bleiziffer","year":"2018","journal-title":"Heart"},{"issue":"29","key":"ref8","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1093\/eurheartj\/ehaa544","article-title":"Long-term outcomes after transcatheter aortic valve implantation in failed bioprosthetic valves","volume":"41","author":"S Bleiziffer","year":"2020","journal-title":"Eur Heart J"},{"issue":"18","key":"ref9","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1016\/j.jacc.2017.02.057","article-title":"Transcatheter aortic valve implantation within degenerated aortic surgical bioprostheses: PARTNER 2 Valve-in-Valve Registry","volume":"69","author":"J G Webb","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"ref10","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.jcin.2017.03.018","article-title":"1-Year results in patients undergoing transcatheter aortic valve replacement with failed surgical bioprostheses","volume":"10","author":"G M Deeb","year":"2017","journal-title":"JACC Cardiovasc Interv"},{"key":"ref11","first-page":"S1","article-title":"Transcatheter treatment of balloon-expandable valve structural degeneration: a single-center case series","volume":"67","author":"M Erlebach","year":"2019","journal-title":"Thorac Cardiovasc Surg"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1724038.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T00:16:25Z","timestamp":1655165785000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1724038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,24]]},"references-count":11,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2022,6,1]]},"published-print":{"date-parts":[[2022,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1724038","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"type":"print","value":"0171-6425"},{"type":"electronic","value":"1439-1902"}],"subject":[],"published":{"date-parts":[[2021,2,24]]}}}