{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:41:59Z","timestamp":1654648919656},"reference-count":8,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Parkinson's disease (PD) is the most common cause of parkinsonism, a clinical syndrome that includes bradykinesia, tremor, and postural instability. Secondary causes of parkinsonism include chronic traumatic encephalopathy. However, clear physiopathologic association between spinal cord injury (SCI) and PD has not been well described yet. We describe a rare\/unusual case of a patient with C7\u2013D1 fracture\/listhesis who, 12 days after the trauma, developed a progressive cognitive impairment together with mandibular tremor. Seven days after the onset of symptoms, because of the persistence of mandibular tremor and Glasgow Coma Scale (GCS) score of 4, therapy with L-DOPA\/benserazide was started, which resulted in gradual reduction of symptoms and complete recovery of consciousness. This could be the first report of PD appearing only 12 days after an SCI in the acute stage. Early differential diagnosis on the first manifestations of this kind of symptoms should be considered in patients with SCI to set up the right therapy essential for improving the outcome and preventing devastating consequences. This might also provide insights into the potential pathophysiologic responses of the brain after primary (immediate) and secondary (delayed) damages.<\/jats:p>","DOI":"10.1055\/s-0041-1724108","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T23:58:09Z","timestamp":1637193489000},"page":"298-300","source":"Crossref","is-referenced-by-count":0,"title":["Acute Parkinsonism in a Patient with Spinal Cord Injury: A Case Report"],"prefix":"10.1055","volume":"83","author":[{"given":"Francesco","family":"Perrotta","sequence":"additional","affiliation":[{"name":"Emergenza-Urgenza, Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Paolo","family":"Perrini","sequence":"additional","affiliation":[{"name":"Anestesia e Rianimazione, Universit\u00e0 degli Studi di Foggia Facolt\u00e0 di Medicina e Chirurgia, Foggia, Puglia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lea Pia","family":"Cantatore","sequence":"additional","affiliation":[{"name":"Anestesia e Rianimazione, Universit\u00e0 degli Studi di Foggia Facolt\u00e0 di Medicina e Chirurgia, Foggia, Puglia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,11,17]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/S0140-6736(14)61393-3","article-title":"Parkinson's disease","volume":"386","author":"L V Kalia","year":"2015","journal-title":"Lancet"},{"issue":"06","key":"ref2","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1002\/ana.24396","article-title":"Traumatic brain injury in later life increases risk for Parkinson disease","volume":"77","author":"R C Gardner","year":"2015","journal-title":"Ann Neurol"},{"issue":"12","key":"ref3","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/sc.2016.74","article-title":"Spinal cord injury and Parkinson's disease: a population-based, propensity score-matched, longitudinal follow-up study","volume":"54","author":"T S Yeh","year":"2016","journal-title":"Spinal Cord"},{"issue":"05","key":"ref4","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1002\/jcp.24830","article-title":"Alpha-synuclein as a pathological link between chronic traumatic brain injury and Parkinson's disease","volume":"230","author":"S A Acosta","year":"2015","journal-title":"J Cell Physiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fnins.2015.00059","article-title":"Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease","volume":"9","author":"S Gallegos","year":"2015","journal-title":"Front Neurosci"},{"issue":"12","key":"ref6","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1002\/mds.26424","article-title":"MDS clinical diagnostic criteria for Parkinson's disease","volume":"30","author":"R B Postuma","year":"2015","journal-title":"Mov Disord"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1136\/jnnp.2007.131045","article-title":"Parkinson's disease: clinical features and diagnosis","volume":"79","author":"J Jankovic","year":"2008","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"09","key":"ref8","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1288\/00005537-197209000-00004","article-title":"Nystagmus after experimental cervical lesions","volume":"82","author":"M Igarashi","year":"1972","journal-title":"Laryngoscope"}],"container-title":["Journal of Neurological Surgery Part A: Central European Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0041-1724108.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T00:14:16Z","timestamp":1654647256000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0041-1724108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,17]]},"references-count":8,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2022,6,7]]},"published-print":{"date-parts":[[2022,5]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0041-1724108","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2193-6315","2193-6323"],"issn-type":[{"value":"2193-6315","type":"print"},{"value":"2193-6323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,17]]}}}