{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T03:20:29Z","timestamp":1765423229079,"version":"3.44.0"},"reference-count":25,"publisher":"Mathematical Modelling and Numerical Simulation with Applications","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pediatr Genet"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Growth charts are used to detect growth impairment, overweight, and obesity among Down syndrome (DS) children belonging to different population groups. Due to nonavailability of similar information, age, and gender specific body mass index (BMI) charts for DS children of Indian origin, based on serial data, have been developed. A total of 752 boys and 373 girls diagnosed as cases of DS at &lt;1 month to 10 years of age enrolled from the \u201cgenetic clinic\u201d were followed up in the \u201cgrowth clinic\/growth laboratory\u201d of the institute, following a mixed-longitudinal growth research design. BMI was calculated from body weight and length\/height measured at 6-month-age intervals by using standardized techniques and instruments. Age and sex-specific percentile growth charts for BMI were generated for age range &lt;1 month to 10 years by using the LMS method. DS children remained wasted (BMI &lt;3rd percentile) up to 6 months of age; thereafter, BMI increased to exhibit close similarity with their normal Multicentre Growth Reference Study (World Health Organization 2006) and Indian Academy of Pediatrics (2015) counterparts up to 5 to 10 years, respectively. The percentage of obese DS girls (8.76%) outnumbered boys with DS (4.1%). The use of age and gender specific BMI growth charts may be made for comparative purpose, to assess nutritional status of Indian children with DS, to initiate suitable need-based intervention to improve their overall health and for timely institution of target interventions to prevent growth faltering in this vulnerable population.<\/jats:p>","DOI":"10.1055\/s-0041-1724115","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T08:55:17Z","timestamp":1613811317000},"page":"261-266","source":"Crossref","is-referenced-by-count":2,"title":["Percentile Charts for Body Mass Index of Indian Down Syndrome Children"],"prefix":"10.53391","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1991-0584","authenticated-orcid":false,"given":"Harvinder","family":"Kaur","sequence":"additional","affiliation":[{"name":"Child Growth and Anthropology Unit, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil Kumar","family":"Bhalla","sequence":"additional","affiliation":[{"name":"Child Growth and Anthropology Unit, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inusha","family":"Panigrahi","sequence":"additional","affiliation":[{"name":"Genetics and Metabolic Unit, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"31409","published-online":{"date-parts":[[2021,2,19]]},"reference":[{"issue":"05","key":"ref2","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1097\/00001665-200209000-00004","article-title":"Age-related changes in anthropometric measurements in the craniofacial regions and in height in Down's syndrome","volume":"13","author":"L G 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